Xiao Wang
@WangXiaoLab
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Associate Professor at MIT Chemistry and Core Member at Broad Institute of MIT and Harvard
Boston
Joined June 2018
RT @NatureBiotech: The July issue is live On the cover, Chen et al. have developed a precise chemo-enzymatic metho….
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RT @GraceKC: Can we use RNA to insert kilobases of DNA into the human genome, opening up a new way to engineer cells or treat disease?. Exc….
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RT @wenbowang11: Thrilled to share our latest preprint regarding STAgent, a multimodal AI agent for spatial transcriptomics.: . (1/9) Check….
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RT @D_Rothschild_: My postdoctoral work is finally out! Please consider retweeting. I am very proud of this project. I want to thank my wo….
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RT @cpnoct: Thrilled to share the latest work out of my lab at @CellCellPress on neuropeptidergic neurons in the dorsal raphe that regulate….
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RT @CellPressNews: "Biotechnologist and molecular biologist Xiao Wang seeks to understand the life cycle of cellular RNA". Read our intervi….
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Also thanks so much for the news & view written by Bei Chen and Tao Pan commenting on this work and our previous multi-tail constructs
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Congrats to the team led by talented graduate students @HongyuChenChem @LDangliang @AbhiAditham and critical contributions from everyone. Big thanks to our collaborators on the covid vaccine demo @mircoscopy @zhangf @TheXavierLab, funding from @OnoPharmaFound, Klarman Cell.
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Happy to share CAST as the "BLAST" tool for spatial omics, searching and aligning similar patterns across datasets while revealing their differences with prototype demo of querying new data against reference spatial atlas and comparative spatial studies👇
CAST enables physical alignment of spatial omics data across replicates, techs, modalities at single-cell resolution. Such accurate alignment enables spatial atlas searching, unbiased DEG identification, and reconstruction of spatial multi-omics. DM for questions and collabs!
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RT @NatureBiotech: Chemical and topological design of multicapped mRNA and capped circular RNA to augment translation .
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Chapter 2 of branched RNA: chemically modified branched cap for multi-capped mRNA and capped circular RNA (QRNA)--the cellular translation machinery is surprisingly tolerant of unnatural structures! Beyond enhanced performance, the mechanism is intriguing:
Synthesizing RNA can be as fun as LEGO puzzles! This work is co-led by my incredible colleagues @LDangliang and @AbhiAditham . Huge thanks to my supervisor @WangXiaoLab for such amazing ideas. We are also grateful for the editor, reviewers, and all collaborators along the way.
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RT @naturemethods: With the growing availability of spatial omics data from different techniques, CAST offers a computational tool for reco….
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RT @JingyiRen: Spatial omics technology is transforming our understanding of in situ RNA biology. We are grateful for the opportunity to pu….
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RT @xsui98: Excited to share Deep-STARmap and Deep-RIBOmap! We enabled spatial transcriptomic and translatomic mapping of >1K genes in 200….
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RT @ChemistryMIT: Congratulations to Xiao Wang (@WangXiaoLab), the Cabot Assistant Professor of Chemistry and a Core Member of @broadinstit….
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