Sherlock Biosciences
@Sherlock_Bio
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A subsidiary of @orasure, enabling the democratization and decentralization of testing to personalize healthcare and make an impact on global health.
Joined March 2019
#BREAKINGNEWS Sherlock Biosciences makes history for first ever #FDA authorized use of #CRISPR technology. Emergency Use Authorization granted for test kits which use the SHERLOCK™ CRISPR-based method to rapidly identify the virus that causes #COVID19
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Congratulations to our co-founder @PardisSabeti on her election to The National Academy of Medicine (@theNAMedicine) for her pioneering work in genomics, information theory, #diagnostics, rural surveillance, and education. @broadinstitute
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We're thrilled that our team's work on the INSPECTR assay developed in partnership with @wyssinstitute researchers is now published in @NatureBiotech. This novel molecular diagnostic enables highly-accurate detection of pathogens at the point of need.
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Study by @pardissabeti in @Nature: #CRISPR diagnostics proven to perform thousands of tests simultaneously on over 100 targets, including #COVID19. By screening large sample sets for many pathogens at once, broader detection enables deeper insight.
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Sherlock Biosciences #BreakingNews: Integrated DNA Technologies @idtdna partnership for large-scale manufacturing of @US_FDA authorized #COVID19 #CRISPR diagnostic test.
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Sentinel, an early warning & response initiative led by @broadinstitute @acegid @christian_happi & our Co-founder @PardisSabeti @sabeti_lab was selected by the @ParisPeaceForum to scale up diagnostic & sequencing capacities. Congratulations to the team!.
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Our co-founder Jim Collins’ lab adapted our namesake technology to detect SARS-CoV-2, designing an easy-to-use diagnostic device that can use saliva samples to give a result for #COVID within an hour. Read more in @GENbio and watch the video of the prototype from @wyssinstitute.
#COVID19 Test Detects Emerging Variants Using SHERLOCK and Saliva. Engineers at @MIT and @harvardmed have designed a test that can detect #SARSCoV2 from a saliva sample in about an hour with the same accuracy as the #PCR tests now used. Learn more: #CRISPR
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Thank you @johncumbers of @synbiobeta writing in @forbes for sharing how our @binxhealth partnership will offer 1st ever 20-minute tests in doctor’s offices, supermarkets, & workplaces using #CRISPR #GeneEditing technology
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Congratulations to our Co-founder @zhangf on #1 in @NatureBiotech's Top 20 translational researchers of 2020 and to our Co-founder & @wyssinstitute faculty member Jim Collins on being named to @clarivate's 2021 Highly cited Researchers list!
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Today we announced a global strategic partnership with @binxhealth to develop the first-ever CRISPR-based point-of-care test for COVID-19. #CRISPR
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Congratulations, @wyssinstitute for bringing innovation out of the lab and into the real world to fight #COVID19. Thank you for including us and our collaboration with @IDTDNA in the start-up spotlight for 2020’s “Impact In The Age Of Coronavirus” Report.
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Hear our co-founder Jim Collins discuss the innovations bringing the tools of #SyntheticBiology and AI to the fight against the novel coronavirus. #COVID19 #SARSCoV2 #ArtificialIntelligence #MachineLearning #Diagnostics #Biotechnology #EngineeringBiology.
What if we could design a face mask that changes color when the coronavirus is detected in the wearer? With the help of synthetic biology, that's exactly what this team of scientists is creating. Watch Jim Collins's full talk here:
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The Bill & Melinda @GatesFoundation has awarded us a $5 million grant to advance our #synbio INSPECTR™ platform for instrument-free #COVID19 #diagnostics to support our promise of delivering testing anywhere, including low- and middle-income countries.
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We are #hiring a Principal Scientist - Assay Development to work with our molecular and engineering teams to develop next generation diagnostics on our CRISPR and Synthetic Biology technology platforms. Join our Team! #CareersinSTEM #AssayDevelopment.
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Our CEO @BryanDechairo shared with @Inside_PM how Sherlock is using #CRISPR diagnostic technology developed at @MIT and @broadinstitute by Co-Founders including @PardisSabeti and Jim Collins of @wyssinstitute to develop #pointofneed diagnostics.
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Since co-inventing our SHERLOCK #CRISPR platform, our co-founder Jim Collins led a team to apply the 2018 one-pot, ultrasensitive #diagnostic method to Malaria, working towards the @WHO goal to eradicate this serious and sometimes fatal disease.
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Sherlock Biosciences has been selected as a World Economic Forum 2020 Technology Pioneer. Learn about the @WEF #techpioneers20 firms shaping the future by advancing technologies.
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We're thrilled to have @adsilverman627 and @SynBioCarlsons on our team to transform global health with #synbio and #CRISPR #diagnostics!.
It's been a little over a week since @adsilverman627 defended and left us, @jewettlab_NU and @NUSynBio to save the world @Sherlock_Bio (with @SynBioCarlsons) and it feels like a year! Excited to see where you take #cellfree #synbio diagnostics!
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Today we announce a coalition with 221b Foundation, @open_phil, & @idtdna facilitated by @digbijaymahat to provide our #CRISPR SARS-CoV-2 #diagnostic kits to the country of Nepal as an essential diagnostic test for combating the #Covid19 pandemic.
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Thank you to @wyssinstitute for enabling us to bring innovation out of the lab and into the real world to fight #COVID19. Read the Year in Review 2020 to learn more about this year’s impact on the future.
2020 was quite a year for all of us - here at the Wyss, we published over 200 papers, obtained 48 patents, launched 11 startups, licensed COVID-19-related tech to 6 companies, and more. Check out the rest of our 2020 highlights here!
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Another exciting innovation for SHERLOCK from our co-founder Jim Collins' lab @wyssinstitute. The miSHERLOCK device uses saliva to test for #COVID19 and variants with minimal instrumentation, providing at-home results in 1 hour.
Diagnosing the Delta variant could be as easy as spitting: a new device from the Wyss and @MIT detects SARS-CoV-2 variants in users' saliva in about an hour, no lab equipment needed. #COVID19 #Diagnostics #DeltaVariant .
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Proud and excited to announce The 221b Foundation, a non-profit organization committed to providing access to #CRISPR #diagnostic tech to end the #COVID19 pandemic with profits supporting diversity in STEM with @Scratch @ScratchEdTeam.
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Thank you @StraitonJenny for including us in this important piece on the need for scalable, rapid COVID-19 testing and for highlighting our efforts to bring our point-of-care #CRISPR #diagnostic INSPECTR technology into the home to combat #COVID19.
The key to successful #masstesting for #COVID19 will be a rapid and reliable test – such as the point-of-care #CRISPR diagnostic test under development by @Sherlock_Bio and @binxhealth … (4/6)
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.@omarabudayyeh & @jgooten found therapeutic potential for a new CRISPR System! Their work with fellow co-founders Deborah T. Hung, James Collins, @PardisSabeti, @zhangf on the SHERLOCK method demonstrated CRISPR's power in #diagnostics. Great to see CRISPR innovation continue!.
Excited to share work on a new CRISPR enzyme, Cas7-11, that targets RNA and redefines how we think about CRISPR systems, out now in @Nature. Newest CRISPR tool among others like Cas9, Cas12, and Cas13. No official relation to @7eleven. W/@jgooten Read:1/n
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Congratulations @mammothbiosci. Another demonstration of the value of CRISPR and its potential to transform #diagnostics.
We’ve reached unicorn status through a successful $195 million series C/D raise! . . This financing and our extremely talented team will supercharge our protein discovery engine and accelerate the creation of next-generation #CRISPR products.
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Read the latest publication from our co-founder Jim Collins' and a team of scientists from @wyssinstitute & @MIT in @ScienceAdvances about miSHERLOCK, a simple, low-cost CRISPR-based diagnostic for #COVID19 that uses saliva & provides results in one hour.
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Congratulations to the Sherlock team members and our partners at @DartmouthHitch who contributed to the clinical validation study, "High-Throughput CRISPR-Cas13 SARS-CoV-2" published in @Clin_Chem_AACC. Read more:.
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Great to see our co-founder Dr. @PardisSabeti featured in the Blue Cross MA @BCBSMA “Heroes on the front line” series for her work in #COVID research! “We're deep in it,” she says. “It’s a race against time.”
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“Synthetic biology is going to become one of the dominant technologies for this century and will be harnessed to address some of our biggest challenges.” Our co-founder Jim Collins discusses @Sherlock_bio & #AI's power w/ @LynnThoman on @3_Takeaways.
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In 2021, we are focused on our 221b Foundation commitments to equity in science, medicine and society; the eradication of #COVID19; and the increased inclusion of underrepresented communities in STEM. Learn more:
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With the vaccine rollout underway, widespread surveillance testing remains important tool to stop #COVID19 spread says @MPVann @abcnews. We are advancing our INSPECTR platform to bring low-cost, instrument-free, self-#diagnostic tests to the world. #synbio
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Congratulations to our co-founder @zhangf and to all the new members elected into the @theNAMedicine today!.
Congratulations and welcome to the 100 new members elected today to the National Academy of Medicine! #NAMmtg
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"It’s undoubtedly unusual for a startup. " writes @BosBizAllison in @bosbizjournal about The 221b Foundation, our non-profit that will direct funds from our #COVID19 products to programs that support racial and gender #equity in #STEM. ($)
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Today we take an exciting step to democratize & decentralize #diagnostics. With our #acquisition of @sensedx1, we will accelerate the development of powerful molecular #diagnostics to transform healthcare and empower consumers around the world. #Biotech.
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Our CEO @BryanDechairo spoke with @GrinsteinJ for his story in @GENbio, Sherlock Biosciences Is Cracking At-Home and Field Diagnostics. Read about the #CRISPR advancements our team has made to bring our tests to the point-of-need:.
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Congratulations to BE GREATEST Award winner, @adsilverman627! Adam is recognized by his team for going above & beyond in his role as Chemical Safety Officer in our new headquarters. Are you driven to #BEGREAT & bring out the best in your team?.Join us: .
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In @NatureBiotech, our Co-founder Jim Collins explored the power of #CRISPR to drive innovation in decentralized #diagnostics. At Sherlock, we are harnessing CRISPR to improve the sensitivity & specificity of diagnostic tests for the point of need.
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Our CEO @rahulkdhanda recently spoke with Karen Tkach Tuzman @_Ktktktktk @BioCentury about mass asymptomatic screening for #COVID19. His take: "[It's] more valuable if it's used more broadly." Read more:
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This new programmable platform from our co-founder Jim Collins' lab at @wyssinstitute uses synthetic biology & CRISPR-based SHERLOCK sensors that can be embedded into masks and clothing to detect toxins & pathogens.
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Congratulations to our co-founder @zhangf and the entire team at @arbortx led by @devynsmith15 on securing Series B funding to turn CRISPR-based gene editing tools into medicines that can be used in the real world. Read more by @jasonMMast:
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High throughput #CRISPR #diagnostics with minimal equipment costs are critical to increasing #COVID19 testing capacity. We've validated our assay to provide a fast, user-friendly, inexpensive method to detect SARS-CoV-2. Read our new White Paper here:
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Congratulations, @rahulkdhanda! @BosBizJournal named our CEO in the 2020 Power 50. It’s an honor to be recognized with fellow nominees, who are coming together to rise to the challenges we face and commit to meaningful community impact during this unprecedented time. #BBJPower50.
In a year unlike any other, many extraordinary leaders in Greater Boston's business community are meeting the challenges of 2020 head on.
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Today marks an exciting step for rapid-result CRISPR #diagnostics to expand access to #COVID19 testing. Out partner @binxhealth has submitted for Emergency Use Authorization from the @US_FDA for the 1st ever #CRISPR-based point-of-care test for #SARSCOV2.
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Thrilled to welcome our new CEO @BryanDechairo to Sherlock’s Boston headquarters today! We’re excited to have Bryan helming the ship as we continue our mission to disrupt molecular diagnostics.
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Read about our co-founder @PardisSabeti innovation using SHERLOCK technology to perform multiplexed nucleic acid testing at scale to prevent future outbreaks in @JAMA_current “Virus Surveillance and Diagnosis With a CRISPR-Based Platform”
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We are honored to add @FastCompany’s Most Innovative Companies for 2021 to our award-winning year. We owe this recognition to our amazing team and their commitment to driving innovation that will transform global health. #diagnostics #FCMostInnovative.
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Our co-founders Jim Collins and @rahulkdhanda discuss the power of engineering biology to make pragmatic, transformative advances in #diagnostics, bringing testing anywhere and everywhere it is needed. #CRISPR #synbio.Link to Video:
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Simple at-home tests for the coronavirus could be the key to expanding testing and impeding the spread of the pandemic say @Kotlikoff @michaelmina_lab in their @nytimes opinion piece.
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Widespread #diagnostic testing remains vital to detecting and tracking variants and containing the pandemic. Read "What #COVID19 testing looks like in the age of vaccines" in @voxdotcom by @SaraMorrison.
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Thank you @siliconrepublic for including Sherlock Biosciences as a @wef #techpioneer2020 transforming the world through innovations in healthcare!.
7 start-ups transforming the world of healthcare
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Real-Time, Multiplexed SHERLOCK for in Vitro Diagnostics, published in @JMDiagn, shares our team's use of CRISPR to enable a real-time, single-step nucleic acid detection method for SARS-CoV-2 with a rapid time to result in less than 30 minutes.
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Thank you @FastCompany for naming our novel #synbio platform one of the best innovations in health for The Next Big Thing in Tech Awards! Ambient temp., fully disposable molecular #diagnostics have the power to improve human health worldwide. #FCTechAwards.
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Watch a replay of the @BioCentury webinar “Good Test Hunting: The Road to Testing that Enables Reopening” featuring our CEO @rahulkdhanda discussing how #CRISPR #diagnostics for #COVID19 testing can support a return to normalcy.
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Our team members' diverse experiences foster ideas & innovation. We strive to #BeGreat to make a positive impact on human health. Meet one of our newest team members, Mary Natoli, Scientist I - Sample Preparation! Here's her vision for our technology.
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Join @HarvardGSAS alum Jenny Pena today at Harvard's @thebiotechclub Career Fair. We’re looking to expand our team of business, technology, disease and industry experts. Interested in helping us build Sherlock and transform public health? Come say hi.
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On #WorldCRISPRDay, learn how ambient temperature amplification technology developed by our Co-Founder Jim Collins @wyssinstitute enables #CRISPR detection at room temperature. Tune in to @Synthego's CRISPR Cuts interview with our CEO @BryanDechairo:.
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A round of applause for our team! Your dedication to global health made Sherlock Biosciences one of @FastCompany's Most Innovative Biotechnology Companies for 2021. Read more about our recognition as #FCMostInnovative here:
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We are thrilled to welcome Tiffany Summerville as our Executive Director, Head of Human Resources. Tiffany shares @sherlock_bio’s belief that people are the foundation of our success and will help drive our next phase of growth.
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Thank you @globalergnet and @TalDimensions for naming Sherlock's Magnify Diversity, Equity, Engagement and Inclusion initiative one of the 2022 Top Ten Diversity Action Award winners! Congratulations to our team on earning this recognition for advancing #DEI in the workplace!
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Pradeep Ramesh is presenting a novel #DeepLearning model developed by our #AI research group at @ChEnected's #SEED22 #synbio. Register to learn how this tool is being leveraged to accelerate next-gen molecular Dx assay development from weeks to hours:
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“Managing a team at Sherlock is really a privilege,” says Christine Coticchia. Thinking about your next role? Join Christine and the Sherlock team in meeting the urgent need for diagnostics to transform global health. Apply today.
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In @GailLdutton's latest @GENbio piece, Synthetic Biology Engineers the Next Genomic Revolution, our co-founder Jim Collins describes how integrating #AI and synthetic biology can advance the development of next generation therapeutics and diagnostics.
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A pilot study of our CRISPR SARS-CoV-2 test kit performed by Dartmouth-Hitchcock Health @DartmouthHitch showed 100% accuracy in real patient samples #COVID19.
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Our CEO @rahulkdhanda shares his insights on the #COVID19 #diagnostics landscape, the future for at-home testing and the role biotech can play in racial justice and equity. @julemieux1 @GENbio.
Thank you @julemieux1 for a great conversation on the current #COVID19 #diagnostic landscape and @Sherlock_Bio's commitment to improve global health through #CRISPR and #synbio solutions for decentralized testing. @GENbio.
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We've validated our #CRISPR #diagnostic assay to provide a fast, user-friendly, inexpensive method to detect SARS-CoV-2, the virus that causes #COVID19. Read our new White Paper here: .
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Computational analysis shows our #diagnostic test detects #COVID19 variants. Our CTO Will Blake and Senior Machine Learning Scientist Pradeep Ramesh discuss how we are applying AI and advanced computational tools to respond to new and emerging threats. #CRISPR
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Our Sherlock Biosciences team is achieving GREAT things together and we have an exciting year ahead. Interested in doing groundbreaking work with a team that will support you to be your best? Join us on our mission to transform global public health!.
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Bringing to market the first #CRISPR application approved by the FDA was a proud moment in a challenging 2020! Thank you @meganmolteni for highlighting the breakthrough in your @WIRED recap of CRISPR’s breakout year. #diagnostics
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Thank you @CrisprMedicine for including us in your recap of #CRISPR breakthroughs in 2020 for our #COVID19 #diagnostic, the first CRISPR application approved by the FDA.
2020 was an incredible #CRISPR year - CRISPR broke new ground in medicine, saw victories in clinical trials and won the #nobelprize2020 in Chemistry. These and more are our highlights of 2020. #crisprmedicine .
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From CEO @BryanDechairo and everyone at Sherlock, we'd like to wish you Happy Holidays — a chance to gather with your loved ones, and a wonderful time to reflect and create new goals and dreams. #happyholidays #holidayseason #holiday
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We’re thrilled that Dr. Martin Madaus will be joining Sherlock as the company’s Chief Operations Officer to assist in the rapid expansion of Sherlock in the next 12 months.
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Call for #HBCU students to explore a #biotech career with our team! We've partnered with @MALifeSciences to support the next generation of Life Science professionals with a range of internship opportunities. Apply by 5/16 for Summer and 6/20 for Fall:.
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Our CEO @BryanDechairo spoke with @GenomeWeb's @tweetMadeleine about our newly licensed ambient temperature amplification tech from @HarvardTechXfer @wyssinstitute and how it enables us to create #diagnostic tests for #InfectiousDiseases #Biotech.
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"The two-pronged testing strategy — diagnostics and screening — should become the playbook for responding to pandemics." @cmyeaton @dylanbgeorge.We are developing INSPECTR, a #synbio #diagnostic test platform to help meet demand for low-cost self-tests everywhere they're needed.
Just out - @dylanbgeorge and I write that covid will not be our last threat. We need to use the American Rescue Plan to fund and scale testing, genomic surveillance and outbreak analytics to get us through this crisis and ready for the next.
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Congratulations to BE GREATEST Award winner, Mary Wilson! Mary is recognized by her team for going above & beyond setting up biosafety processes in our new headquarters. Are you driven to #BEGREAT & bring out the best in your team? #WomenInSTEM.Join us:
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Our entire team shares our CEO @rahulkdhanda's commitment to antiracism. On Building Biotech, he shared why we strive to recruit BIPOC talent, invest in education for #WomenInSTEM, and dismantle structural racism by building better healthcare. Read his letter to our staff.
Thank you @nabsicle and @Jack_O_Meara for the incredible fun I had on your Building #Biotech @joinClubhouse event. Thank you to all the participants. As promised, below is the letter I sent to my company after the horrible events surrounding George Floyd's death.
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Sherlock Biosciences stands in solidarity with the Asian-American Pacific Islanders (AAPI) who live in our communities and work in our biotech industry. We pledge to stand up against anti-Asian hate & discrimination to ensure a safe and inclusive community. #StopAAPIHate.
BIO stands with AAPI communities against hate and acknowledges the work we need to do to combat it. Read more:
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We celebrate the #LGBTQ+ community during #PrideMonth & voice our commitment to advancing #DEI in #biotech by advocating for LGBTQ+ visibility and representation. Read more from @IAmBiotech 2021 Diversity Report:.
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This #AAPIHeritageMonth, we celebrate the diverse cultures in the #AAPI community. We honor the contributions to #STEM made by Asian American scientists like virologist Dr. Flossie Wong-Staal who's research was critical to combatting #HIV. #DEI Read more:.
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Sherlock Biosciences celebrating the Groundbreaking of our new Headquarters located in Arsenal on the Charles. Thank you to our new neighbor @_BranchLine for hosting us!.
Yesterday @Sherlock_bio broke ground on our new HQ! .Thank you to our amazing team of partners who are building a space that reflects our culture, values, and commitment to scientific innovation: our landlord Alexandria Real Estate Equities, @WiseBuilds, @CBRE & OTJ Architects.
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Our CEO @BryanDechairo will speak on a panel about the role of #CRISPR #diagnostics in dental innovation & technology development for #oralhealth at .@ForsythResearch's Dentech 2022 Conference on September 15 at 10am EST. Register here: .
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Today we announced the discovery of novel CRISPR-Cas enzymes that enhance, simple multiplex #diagnostic solutions, furthering the utility of our #CRISPR toolkit in molecular diagnostics and point-of-care settings.
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“No one questioned whether we could do it. Everyone said this is how we’re going to do it.” As true today as it was 1 year ago when we made history with the first FDA authorized use of #CRISPR technology.
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Our proprietary #CRISPR & #SynBio engineering biology tools for DNA & RNA detection will bring next-generation diagnostics to the point-of-need. We will transform diagnostics & #GlobalHealth by helping people access health information wherever they are.
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Congratulations to our Co-founder David Walt, a 2021 winner of the Kabiller Prize in Nanoscience and Nanomedicine! @IINanoNU recognizes Walt as a pioneer for his work developing ultrasensitive single-molecule array detection technology and its impact on medicine and biology.
Wyss Core Faculty member David Walt is awarded the prestigious Kabiller Prize at @NorthwesternU for his extraordinary impact on modern medicine.
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Thank you @synbiobeta for recognizing The 221b Foundation. Today 221b co-founding board member @rahulkdhanda spoke at #synbiobeta2020 about our commitment to eradicate #COVID19 and further racial and gender #equity in STEM.
.@Sherlock_Bio recently launched The 221b Foundation, a non-profit organization committed to providing access to #CRISPR #diagnostic tech to end the #COVID19 pandemic with profits supporting diversity in STEM. #synbiobeta2020
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Thank you @BioCentury for including us in your top 10 stories of 2020. Just 2 months after "CRISPR-based diagnostics are poised to make an early debut. " published, we made history with the first FDA-authorized use of #CRISPR technology with our #diagnostic to fight #COVID19.
2020 was a year most of us would like to forget. BioCentury reflects on last year and revisits the top 10 articles of 2020 Number 10 goes to. Download top 10: @pharmaceutical @EuropaBio #Biotechnology #pharmaceuticals #COVID19Vaccines @V2019N
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Sherlock Bioscience's team received a $7.5 million grant advance from @open_phil to develop at-home #COVID19 tests. We are thrilled to invest in our #Sherlock Innovation Lab by hiring local experts to bring #INSPECTR to the public.
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In partnership with @AlbotTechnology, our #CRISPR technology will generate 1 million tests per month in India as they confront the challenges posed by new #COVID19 variants.
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At Sherlock, our team is committed to helping people access health information wherever they are. We aim to transform health outcomes worldwide with our #CRISPR, #SynBio and #AI tools for DNA & RNA detection by bringing next-generation #diagnostics to the point of need.
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