Inside Precision Medicine
@Inside_PM
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Exclusive news, features, and analysis on the research, tools, regulations, and applications driving precision medicine. From the publisher of @GENBio
New Rochelle, NY
Joined April 2014
🎧 Behind the Breakthroughs Step into the minds shaping the future of medicine. Listen on your preferred platform: Apple → https://t.co/mHHfEvcLPF Spotify → https://t.co/xwS0ZZQ143 IPM → https://t.co/L7YbogYq8F
#PrecisionMedicine #BehindTheBreakthroughs #MedTech #Biotech
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New Precision Target Found in Aggressive Kidney Cancer Profiling of renal medullary carcinoma (#RMC) highlights TROP2 and Hippo signaling as key vulnerabilities, supporting new therapeutic strategies @PavlosMsaouel
#kidneycancer #RNAseq
https://t.co/2QtNoZzg0z
insideprecisionmedicine.com
Profiling of renal medullary carcinoma highlights TROP2 and Hippo signaling as key vulnerabilities, supporting new therapeutic strategies.
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High Levels of Three Biomarkers Triples Risk for Heart Attack Levels of lipoprotein a, remnant cholesterol, and high-sensitivity C-reactive protein help show who is at highest risk for #heartattack
@Kazibwe_md @wakeforestmed
#biomarkers #heartdiseases
https://t.co/ho38UHVqTq
insideprecisionmedicine.com
Levels of lipoprotein a, remnant cholesterol, and high-sensitivity C-reactive protein help show who is at highest risk for heart attack.
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Antibiotic Prodrug Uses Bacteria's Resistance Genes to Turn Against Itself A structurally modified form florfenicol hijacks the #resistancemechanism in #Mabscessus to amplify the drug’s effect “in perpetuity" @RichardLeeLab @StJudeResearch
#antibiotics
https://t.co/glW6Ml1oYW
insideprecisionmedicine.com
A structurally modified form florfenicol hijacks the resistance mechanism in M. abscessus to amplify the drug’s effect “in perpetuity.”
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AI Detects Heart Defects with Just a Smartwatch For the first time, @YaleMed researchers have been able to diagnose structural heart disease using the simple ECG sensors found in a #smartwatch
@rohan_khera @AryaAminorroaya
#heartdisease #AI #ECG
https://t.co/7WOK3sAAgH
insideprecisionmedicine.com
For the first time, Yale researchers have been able to diagnose structural heart disease using the simple ECG sensors found in a smartwatch.
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In a Potential Mega Deal, Takeda Buys Innovent Cancer Candidates @TakedaPharma is acquiring at least two late-stage #oncology candidates, IBI363 and IBI34, for $1.2 billion from China’s Innovent Biologics @Innovent_2011
#cancertherapy #clinicaltrials
https://t.co/9yeimoFnny
insideprecisionmedicine.com
Takeda is acquiring at least two late-stage oncology candidates, IBI363 and IBI34, for $1.2 billion from China’s Innovent Biologics.
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Like MAGIC: New AI Tool Reveals How Chromosomal Errors Arise, Offers Clues to Cancer’s Origins MAGIC, an AI-driven system tracking chromosomal abnormalities in single cells, uncovers cancer’s cellular origins @JanKorbel5 @embl
#AI #chromosomes #cancers
https://t.co/4DYYt0JLsu
insideprecisionmedicine.com
MAGIC, an AI-driven system tracking chromosomal abnormalities in single cells, uncovers cancer’s cellular origins.
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Coagulation Factor II Receptor Shows Promise as Ovarian Cancer Target A significant step forward in #ovariancancer research identifies the F2R protein as a potential #biomarker and treatment target @UniSA_CPI
#cancertherapy
https://t.co/154SnUByyO
insideprecisionmedicine.com
A significant step forward in ovarian cancer research identifies the F2R protein as a potential biomarker and treatment target.
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Neuroblastoma Tumor Growth Slowed by High Levels of HIF2α New research indicates that HIF2α may not act as a tumor driver in certain #neuroblastomas as suggested by earlier research @umeauniversity @karolinskainst
#tumorgrowth #geneexpression
https://t.co/4RQU8FbRvS
insideprecisionmedicine.com
New research indicates that HIF2α may not act as a tumor driver in certain neuroblastomas as suggested by earlier research.
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Genomic 3D Mapping Tool Spots Hidden Genetic Disorders A transformative #geneticmapping tool that detects mutations hidden within the spatial conformation of #chromosomes could transform the diagnosis and treatment of #geneticdisorders
@uwsomwwami
#genome
https://t.co/OHzjHW8yDY
insideprecisionmedicine.com
A transformative genetic mapping tool that detects mutations hidden within the spatial conformation of chromosomes could transform the diagnosis and treatment of genetic disorders.
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Curve Biosciences Raises $40M for Blood-Based Chronic Disease Monitoring The startup's "whole body intelligence" platform assesses organ health by associating the origin organ with cell-free DNA methylation #CurveBiosciences #chronicdisease #cfDNA
https://t.co/vhaQXCobxo
insideprecisionmedicine.com
The startup's "whole body intelligence" platform assesses organ health by associating the origin organ with cell-free DNA methylation.
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Glucocorticoid Receptor Findings May Guide Safer, Targeted Drugs The GR forms tetramers, unlocking a new, potentially fertile, ground for the development of new therapies for a range of conditions @Eva46653369 @IBUB_UB
#arthritis #GR #immuneresponse
https://t.co/gz6BLWsj3e
insideprecisionmedicine.com
The GR forms tetramers, unlocking a new, potentially fertile, ground for the development of new therapies for a range of conditions.
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Stem Cell Therapy Lowers Heart Failure Risk After Heart Attack Receiving a stem cell therapy within a week of a heart attack lowered the risk of developing #heartfailure within the next three years @sums_gsia
#stemcelltherapy #heartattack
https://t.co/0B6k3vGSMi
insideprecisionmedicine.com
Receiving a stem cell therapy within a week of a heart attack lowered the risk of developing heart failure within the next three years.
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Potential Spinal Cord Therapy Using Thiorphan Uncovered by Computational Analytics A computational platform matched #geneexpression patterns in #neuralregeneration to find thiorphan, the active metabolite in racecadotril @UCSDMedSchool
#spinalcordinjury
https://t.co/17xeQVIy6a
insideprecisionmedicine.com
A computational platform matched gene expression patterns in neural regeneration to find thiorphan, the active metabolite in racecadotril.
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Deep Learning Flags Breast Cancer Risk Between Triennial Screenings A #deeplearning model predicts if women undergoing triennial #mammography need extra imaging or more frequent screening due to higher interval #breastcancer risk @fjg28_fiona
https://t.co/WMCtRm0dP9
insideprecisionmedicine.com
A deep learning model can predict whether women undergoing triennial mammography might need supplemental imaging or more frequent screening in between due to an elevated risk of interval breast...
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CAR Tregs Show Therapeutic Activity in Rheumatoid Arthritis Patients Co-founded by Jeff Bluestone and 2025 Nobel Laureate Fred Ramsdell, @sonomabio presented early clinical data for #autoimmunedisease treatment #Tregs #immuneresponse
https://t.co/Qc9Cen522Z
insideprecisionmedicine.com
Co-founded by Jeff Bluestone and 2025 Nobel Laureate Fred Ramsdell, Sonoma Biotherapeutics presented early clinical data for autoimmune disease treatment.
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Compact 3D Printer Repairs Vocal Cords During Surgery The smallest 3D bioprinter to date could help surgeons reconstruct tissues removed from the vocal cords in real time during surgery @mcgillu
#bioprinting #biomaterials #vocalcords
https://t.co/WsIgv8uplo
insideprecisionmedicine.com
The smallest 3D bioprinter to date could help surgeons reconstruct tissues removed from the vocal cords in real time during surgery.
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Michael Langer: Biotech Investing in the Data Age The T.Rx Capital co-founder and managing partner explores how techbio, #AI, and global forces shape which #precisionmedicine ideas thrive—or fade @MichaelofLanger
#biotech #drugdevelopment
https://t.co/qHAr1c4HU5
insideprecisionmedicine.com
The T.Rx Capital co-founder and managing partner explores how techbio, AI, and global forces shape which precision medicine ideas thrive—or fade.
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Novel CLIC5 Gene Therapy Uses AAV Technology to Treat Hearing Loss The #genetherapy targets the CLIC5 gene, which maintains the structure and stability of sensory hair cells in the inner ear @KarenAvraham @TelAvivUni @harvardmed
#hearingloss #AAV
https://t.co/cWYlt3dsaE
insideprecisionmedicine.com
The gene therapy targets the CLIC5 gene, which maintains the structure and stability of sensory hair cells in the inner ear.
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Viral Infections Increase Risk of Cardiovascular Disease #Viralinfections such as COVID and more chronic infections like HIV increase a person's risk of #heartdisease
@dgsomucla
#COVID19 #HIV
https://t.co/CxrTAdmrW7
insideprecisionmedicine.com
Viral infections such as COVID and more chronic infections like HIV increase a person's risk of heart disease.
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Tailored Resuscitation Using Capillary Refill Time in Early Septic Shock Targeting capillary refill time, personalized hemodynamic #resuscitation for early #septicshock leads to improved patient outcomes compared to standard care @uc_chile
#CRT
https://t.co/DFSFLCxJp7
insideprecisionmedicine.com
Targeting capillary refill time, personalized hemodynamic resuscitation for early septic shock leads to improved patient outcomes compared to standard care.
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