🎧 Behind the Breakthroughs Step into the minds shaping the future of medicine. Listen on your preferred platform: Apple → https://t.co/mHHfEvcLPF Spotify → https://t.co/xwS0ZZQ143 IPM → https://t.co/L7YbogYq8F #PrecisionMedicine #BehindTheBreakthroughs #MedTech #Biotech

Colorectal Cancer Screening Rates Could Increase Using New Strategies A pair of new studies examines two aspects of the colorectal #cancerscreening process to see if it could be improved @umichmedicine #CRC #colonoscopies https://t.co/7eSNZ6R86t

Hormonal Contraceptives Differentially Impact Breast Cancer Risk A study of more than 2 million adolescent girls and women revealed that the risk for #breastcancer varies among #hormonalcontraceptive formulations @JohanssonAasa @uppsalauni #ovariancancer https://t.co/TuOt1MmvO6

Cancer's Own Machinery 'Hijacked' to Spark Anti-Tumor Response The immune-activating molecule cGAMP reacts to the presence of dsDNA in the cells’ cytoplasm, causing the #immunesystem to fight the tumor @NatalieArtzi @MassGeneralNews #melanoma #tumors https://t.co/mZfahiERfA

Unmasking Pancreatic Cancer’s Sugar Shield: A New Target for Immunotherapy Scientists reveal a sugar-based immune evasion mechanism in #pancreaticcancer and develop an #antibody to restore antitumor immunity @AbdelMohsen_Lab #immunotherapy https://t.co/7JEJzEK3XA

Treatment Intensity for Many Medulloblastoma Patients Reduced at St. Jude A data-driven method to stratify #medulloblastoma patients guides therapy intensity to limit long-term treatment toxicities @DrGilesRobinson @StJudeResearch #chemotherapy #radiation https://t.co/BPQMO9K5mX

Intranasal Vaccine Offers Protection Against Multiple Bird Flu Strains Phase I results show early evidence of an #intranasal vaccine providing broad immunity against multiple strains of the avian #influenzavirus @UMmedschool #vaccines #clinicaltrials https://t.co/I8os9KkcgX

Michael Langer, co-founder of T.Rx Capital, on biotech investing in the data age. Disciplined, data driven, hype resistant. Read more and listen: https://t.co/IAkdNrbxvs #BehindTheBreakthroughs #Biotech #VentureCapital #AI @MichaelofLanger

Variants in Subcellular-Specific Isoforms Contribute to Rare Disease #Raredisease variants can selectively impair one #isoform while leaving another intact, resulting in divergent molecular and clinical outcomes @BostonChildrens @MIT #mitochondria https://t.co/y8zwD56Xj4

“The State of AI in Precision Oncology” virtual summit 📅 Tue, Dec 16 | 11 AM–3 PM ET Guests include @DrAbernethyFDA, @zakkohane, Betsy O’Donnell (@DanaFarber), Dr Connie Lehman (@MassGenBrigham), & David Penberthy! Free: https://t.co/1ngvj2mx1J @AI_PrecisionOnc @dougflora2

Genetic Variants Implicated in Prostate Cancer Among Men with African Ancestry Five genetic variants in #prostatecancer predisposition genes have been identified in men of African ancestry @KECKSchool_USC #geneticvariants #cancerscreening https://t.co/74myWJtn0w

Weak Spot of Metastatic Melanoma Cells Identified A protein involved in #ferroptosis has been revealed as a unique weakness of metastatic #melanoma cells that have spread to the #lymphnodes @marioepalmma @MET_HSPH https://t.co/swDJtVTSLj

First Brain Cell Atlas: Clues to Neurodevelopmental and Psychiatric Disorders Reference atlases for the development of mammalian brains have been published, mapping how diverse #braincells establish their identities during #neurodevelopment @HongkuiZeng https://t.co/AgZFMflriP

How a p53 Mutation Can Sensitize Tumors to Immunotherapy The p53 R273H mutation overstimulates #DNAreplication, creating genomic instability that activates an immune attack against #tumors @bcmhouston #immunotherapy #p53 https://t.co/sCmDfohcTm

Tuberculosis mRNA Vaccine Design Reinvented Using Immunopeptidomics Researchers mapped immune cells' recognition of Mycobacterium #tuberculosis, revealing bacterial fragments that could inform vaccine design @MIT @ragoninstitute #TBvaccine #immunecells https://t.co/24diysDvYS

Key Protein Driving Autoimmune Inflammation Identified The protein ABHD11 is central to the metabolic changes that occur in #autoimmunity, causing T cells to attack health tissue @Nickjonesimmuno @SwanseaUni #Tcells #inflammation https://t.co/qoa0j32WuL

Infections and Antimicrobial Resistance Predicted to Rise Steeply by 2050 Infections and #antimicrobialresistance are both predicted to increase substantially in Europe by 2050, particularly in men and older adults @gmknght #infectiousdisease #antibiotics https://t.co/N9sOGrgSBK

In Vivo Gene Editing for Rare Diseases Begins with Umbrella Clinical Trial The FDA is working with the team that developed the first customized, on-demand #CRISPR based treatment to scale up to clinical trials @AhrensNicklas #genetherapy #rarediseases https://t.co/xcbQPSa6nm

Drug-Releasing Heart Patch Implant Shows Promise After Myocardial Infarction A heart-implanted patch that delivers time-controlled medication could offer a novel approach to post-infarction repair @MIT #heartattack #medicalimplant #drugdelivery https://t.co/00s5C5t3J2

Human Gene Reactivation Could Let the Heart Heal Itself Mount Sinai scientists reactivated Cyclin A2 to make adult heart cells divide, revealing a path toward #genetherapy for heart repair @Hinaheartdoc @IcahnMountSinai #heartfailure #regenerativemedicine https://t.co/27kEVTcnOK

Bioinformatics Tool Simplifies Identification of Structural Genetic Variants A new bioinformatics tool makes identifying complex structural genetic variants causing rare diseases easier @sangerinstitute #bioinformatics #geneticvariants #rarediseases https://t.co/sXwH0Gfumg