ROSALIND 3.0 is out in @nchembio !. Cell-free biosensors are revolutionizing point-of-care diagnostics, but we need greater sensitivity to detect harmful chemicals. Enter: Polymerase Strand Recycling (PSR) — a game-changer for signal amplification! 🌟 .

RT @jerrywliu: 1/10.ML can solve PDEs – but precision🔬is still a challenge. Towards high-precision methods for scientific problems, we intr….

Why is @NUsynbio so great - it's the people. Check out our latest staff profile of our incredible Director of Operations Yael Mayer!.

Check out the latest @RNASociety spotlight of Lucks Lab Alumn Professor Angela Yu! .

Research cuts impact everyone. @NUSynBio trying to get the word out:.

Research is for everyone. Grateful to @WBEZ to talk about why research is important and why stopping hurts people and our leadership as the #1 country for innovation.

RT @ericamhartmann: Speak up! Thanks @LucksLab and @WBEZreset for talking about this.

RT @ProfSeraYoung: Here's to @LucksLab killing it on @WBEZreset today, laying out the damage that the random ransacking of @DeptofDefense g….

Research that benefits everyone is being cut. This is real. The wonderful people at @NUSynBio are working hard to help people. This jeopardizes all of it.

Congrats to @ChappellLab (a @NUSynBio alumni!) on their latest in @NatureBiotech :. Amazing RNA engineering applied to track microbial ecosystems!.

RT @NUSynBio: We are proud to share that Julius Lucks, co-director of @NUSynBio, has been elected a 2024 AAAS Fellow! We are so fortunate t….

Let's make a bunch of cell-free #synbio biosensors, with a robot! New paper out lead by Dylan Brown and Dan Phillips in @ACSSynBio with @MichaelCJewett and a whole cast!.

See the paper in @acsnano !.

New water tech out of the lab covered by @SynBioBeta: . Synbio+nanotech mashup detecting lead down to 1ppb in minutes.

RT @NorthwesternEng: Contamination Detection Tool Enables Highly Sensitive Water Testing. A product of multi-disciplinary Northwestern Engi….

RT @ProfDravid: @NorthwesternEng @LucksLab @NUSynBio @nu_chbe @TrienensInst Great collaboration between Gajendra Shekhawat of SPID/ NUANCE….

RT @NUSynBio: A new joint initiative between @NUFeinbergMed and @NorthwesternEng aims to steer the development of new research “neighborhoo….

One of the many reasons @NUSynBio is so great - the amazing people!. Check out the profile of Christine Akdeniz, our incredible senior education and outreach coordinator:.

See this and much more in this tour de force work:. "RNA folding kinetics control riboswitch sensitivity".

BUT there is a limit - somehow the most sensitive switches still don't sense at the level of aptamer:ligand interactions measured in vivo. We think this might be due to inherent misfolding in the dynamic cellular environment . .

What's really amazing is that if we take these natural strategies as design principles, we can sensitize a range of different riboswitches - all without changing their aptamers!