Matt Regner (he/him)
@RegnerMJ
Followers
234
Following
650
Media
3
Statuses
271
PhD Candidate at UNC Chapel Hill | #singlecell & #compbio | https://t.co/oEPUqd2BP8
Joined January 2020
RT @nomad421: Did @10xGenomics just make newer versions of Cell Ranger open source? (cc @sjackman, @luizirber). Th….
github.com
10x Genomics Single Cell Analysis. Contribute to 10XGenomics/cellranger development by creating an account on GitHub.
0
63
0
RT @NancyZh60672287: What gets erased when you integrate #singlecell data across samples/studies, and can you get it back? When samples are….
0
105
0
RT @CellGenomics: Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes
cell.com
Integrated analysis of single-cell transcriptomes and epigenomes with a simple, permutation-based procedure detects cell-type-specific enhancer-gene associations. This procedure establishes stringent...
0
51
0
RT @TiroshLab: 1. Excited to share our new paper in @Nature! With over 1000 tumors analyzed by scRNA-seq, we provide a systematic pan-cance….
nature.com
Nature - A study identifies 41 consensus gene expression meta-programs that are coordinately upregulated in subpopulations of malignant cells across tumour types, providing a comprehensive picture...
0
356
0
RT @ScienceScottT: Even so, thorough mixing after an 'integration' method only means "good" if you're analyzing technical replicates. Beta-….
science.org
Circadian control of insulin release is mediated by transcriptional enhancers active specifically in pancreatic β cells. [Also see Perspective by Dibner and Schibler]
0
2
0
RT @NatureNV: A human reference pangenome has been generated. In this Forum,@AryaMassarat & @mgymrek tell us how it was built, and Brian Mc….
0
12
0
RT @NatureBiotech: Reactivated transposable elements generate chimeric tumor-specific antigens that are shared among different cancers and….
nature.com
Nature Genetics - Analysis of multiple tumor types, cancer cell lines and adult tissues identifies tumor-specific transposable-element-chimeric transcripts. Mass spectrometry data confirm that many...
0
28
0
RT @dana_peer: @shyam_lab @lawrensonlab @SashaGusevPosts @themis_brown Batch correction is the WORST for cancer because each cancer IS diff….
0
12
0
RT @jamshaid_shahir: As I reflect on my grad school experience during Carolina's day of giving, I'm very grateful to one of my professors @….
biorxiv.org
With the growing number of single-cell datasets collected under more complex experimental conditions, there is an opportunity to leverage single-cell variability to reveal deeper insights into how...
0
2
0
RT @NatureBiotech: SEACells infers transcriptional and epigenomic cellular states from single-cell genomics data ht….
0
20
0
RT @KongGarth: How reproducible are #bioinformatic pipelines really? 🤔. In pursuit of this question, I asked three lab members to run my pi….
0
28
0
RT @vpatelmd: Hey #MedTwitter . Here are the basics of survival curve and hazard ratio interpretation. Trust me it's conceptually easy. Dre….
0
83
0
RT @NanaMatoba: Excited to share our new preprint, where we investigated context-specific gene regulation and QTLs by stimulating 🪄⚡️ the W….
0
14
0
RT @henri_niskanen: Happy to share our work published today in @Nature, where we show that a subset of disease-associated variants in intri….
nature.com
Nature - Frameshift mutations that create arginine-rich basic tails in transcription factors and other proteins can lead to altered phase separation in the nucleolus, which in turn leads to...
0
102
0
RT @sugarciare: After 100s of meetings and discussions with our multidisciplinary group, I’m excited to share the 1st AURORA US network stu….
0
44
0
RT @kahoadley: Newest work from the @HoadleyLab and @MelissaTroester Lab by @AlinaHamilton. @UNC_Lineberger @CompMedUNC.
0
5
0
RT @tangming2005: protip: when ask for help with a bioinformatics problem, explain what you want, what you have tried, and what's the probl….
0
8
0
RT @NatureCancer: ✨ONLINE NOW @NatureCancer – „Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenv….
nature.com
Nature Cancer - Perou and colleagues perform genomic, transcriptomic and epigenetic analyses on pairs of primary and metastatic breast tumors, detecting subtype switching and changes in immune...
0
17
0