Shyam Prabhakar Lab
@shyam_lab
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Associate Director Spatial and Single Cell Systems @astar_gis. Genomics: algorithms, disease markers & mechanisms, genetic diversity [email protected]
Singapore
Joined November 2019
Want to join a global consortium using #singlecell technologies to understand human diversity? Are #AI and #MachineLearning your #s? Come to Singapore! We're looking for leaders to drive v1 of the Human Diversity Atlas within the #HumanCellAtlas.
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RT @metapredict: @tangming2005 Controversial topic, & largely the exception not the rule. As per usual the devil is in the laboratory detai….
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RT @slavov_n: Key factors that contributed to CASP success:. 1. Direct measurements of the prediction target.2. No significant unobserved f….
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Exactly. AI will bring amazing advances in virtually all areas of biology. Eventually. But right now we’re often overfitting. Or using misleading baselines. Or “validating” predictions that we already know to be true. Which feeds more hype, and more bad papers/investments.
Here's an idea. Generally in science, if something doesn't work, we say it doesn't work rather than claiming it does (most current virtual cell foundation models). Do the hard work & then make big claims. 2/.
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RT @msikic: Our RiNALMo RNA language model has been published in Nat Comm Great work by @RJPenic and @TinVlasic,….
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RT @schwabpa: The proposed analogy between interpreting machine learning and biology really does not hold up at all. Understanding biology….
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RT @hoheyn: ⭐ Please consider joining our Single Cell Genomics group as Computational PhD Student!. ♦️ We are hiring 2 Computational Biolog….
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This is an amazing story of a PhD student @astar_gis with passionate desire to use genetics to save lives. Warms the heart to see the great strides that @nalagenetics has made since it first launched so many years ago. 👏🏾👏🏾👏🏾 Astrid, JJ, Sandro, Levana and all!.
🔬 From Lab to Lifesaving Impact: A*STAR GIS Research Powers Precision Medicine in Indonesia 🌍. A groundbreaking discovery by researchers at A*STAR Genome Institute of Singapore (@astar_gis) revealed that a potentially fatal allergic reaction — Dapsone Hypersensitivity Syndrome.
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RT @DrSamuelBHume: This chart shows the improvement in survival for the most common type of lung cancer (adenocarcinoma) from 2000 to 2010….
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RT @cremieuxrecueil: Phenotyping is the vast, minimally-explored frontier in genome-wide association studies. Important thread🧵. Briefly,….
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RT @astar_gis: 📢 GENOME: THE GIS SPEAKER SERIES🧬. Join us at our next seminar by Dr. @junyue_cao, Assistant Professor, The Rockefeller Univ….
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RT @astar_gis: 🔬Low on microbes, high on challenges!🔬.Studying low-biomass environments in microbiome research? The struggle is real when i….
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Remarkable work on kidney cancer mutational signatures being different across the globe. Helps to identify causal mutagens, including apparently some that are still unknown. Which will ultimately help us design public health measures to prevent a large number of cancers. 🙏🏾.
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RT @hoheyn: What if SCALE is a solved problem? 🤔 .Sequencing-Free Single-Cell Genomics with STAMP! 💣 . Now published in @CellCellPress: Our….
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RT @humancellatlas: The HCA 2025 General Meeting brought together 63 speakers and session leads and 631 participants, from 47 countries, to….
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Huge thanks to all the delegates, speakers, chairs, PC members, @humancellatlas staff, mic runners, note takers, and AV staff who made #HCA2025GM possible🙏🏾! . >630 registered. New 10-yr vision for HCA, incorporating community feedback on spatial+disease. We felt the energy 🔥💪🏾!.
Thank you to our Program Committee Co-Chairs, @shyam_lab and @JayShin from @astar_gis for hosting the 2025 HCA General Meeting, and to everyone involved in #HCA2025GM. It has been a truly inspirational meeting.
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The multitalented @reemabaskar on Day 4 of the HCA meeting, showing how MIBI-TOF spatial proteomics can reveal cell-cell communication via extracellular factors. Important complement to spatial RNA!
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RT @humancellatlas: We’re very much looking forward to this afternoon’s HCA Regional Network Meeting: Cross regional synergies. Registratio….
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RT @villanilab: ⭐️NEW PAPER OUT in @Nature⭐️. 🫀What is the relationship between the immune responses in the heart, blood, and tumor in pati….
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RT @SCAID__: Dr.Jong-Il Kim @genomicmed from @SNU_GMI shared the latest progress of the SCAID project including Myocarditis, CTD-ILD, and P….
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… moving from ancestry to sex differences: mosaic loss of sex chromosomes disrupts vaccine response!
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