Scott Tyler (@[email protected])
@ScienceScottT
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Developing new single cell omics methods and bench validating all the hypotheses those techniques give us. Opinions expressed are my own.
Joined June 2018
Working with multiple scRNAseq batches? Having trouble replicating at the bench? Our recent pre-print may show one reason why: ( Findings complementary to @lpachter & Tara’s work finding low dim projections can be unreliable representations.
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RT @RetractionWatch: Announcing the Elisabeth Bik Science Integrity Fund.
retractionwatch.com
Elisabeth Bik We’re thrilled to be partnering with foremost scientific sleuth Elisabeth Bik on a new way to support scientific integrity: The Elisabeth Bik Science Integrity Fund. Bik is a renowned…
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RT @jdpereira: The US mostly funds biomedical research through a large lump payment to the NIH. Panels of scientists and doctors volunteer….
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RT @slavov_n: NIH has stopped considering new grant applications, delaying decisions about how to spend millions of dollars. The freeze oc….
npr.org
The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.
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RT @slavov_n: Some papers seem to be written by authors who did not really know what they wanted to say, and they did not figure it out in….
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RT @mbeisen: This by @SGRodriques laments the (anticipated) failure of models trained on large datasets to reproduce "real biology discover….
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RT @AlecStapp: It's bad that the NIH has pretty much stopped funding young scientists to lead projects
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RT @GorinGennady: Single-cell RNA sequencing is biased (and more so if you count more molecules). But biases aren't just arbitrary artifact….
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RT @CellPressNews: Length biases in single-cell RNA sequencing of pre-mRNA. Check out this research by @lpachter & @GorinGennady in @Biophy….
cell.com
Single-cell RNA sequencing data can be modeled using Markov chains to yield genome-wide insights into transcriptional physics. However, quantitative inference with such data requires careful assess...
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RT @sinabooeshaghi: If you’re frustrated with healthcare, get this: . Health Insurance @ElevanceHealth (formerly Anthem) bamboozled @Caltec….
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RT @JHElisseeff: Seeing data on macrophages and metabolism from single cell. It's somewhat buried in the paper and not obvious from the ti….
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RT @ItaiYanai: Data can be analyzed in endless ways, as this paper reminds us. So while our published paper reports one way to do it, it's….
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RT @genome_gov: Happy Thanksgiving! We are thankful for the opportunity to talk about how cool genomics is with you all the time. Our famil….
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It's a weird and beautiful bag of cheetos ;-) Cool technique! Worth checking out the paper; lots of cool new science can be done with this resolution in living systems!.
Relationship between chromosomes (orange) and the mitotic spindle (green) in four stages of cell division, as seen by Bessel Beam plane structured illumination microscopy
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RT @MicrobiomDigest: Our group of #ImageForensics experts @Thatsregrettab1 , @mumumouse2, @schrag_matthew, and myself are currently posting….
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RT @slavov_n: Help ! . Do you know how to get cloud storage for an academic lab that benefits from non-profit pricing ? .
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RT @anshulkundaje: Nice benchmark of single cell "foundation models" (scGPT, scFoundation) and GEARS (a GNN model)….
biorxiv.org
Advanced deep-learning methods, such as transformer-based foundation models, promise to learn representations of biology that can be employed to predict in silico the outcome of unseen experiments,...
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RT @const_ae: There's a lot of excitement about foundation models and their ability to learn biology 🧬💻. But current tools for perturbation….
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RT @GorinGennady: @leary_jack Saying what amounts to — nobody does this, I don't personally do this, this is not a problem, people who do t….
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