RT @kanishkadey: Excited to share our latest preprint, as part of ENCODE4, on a consensus variant-to-function (cV2F) score for functionally….

RT @i_rodcast: Excited to share our sequence design work published in @Nature. I had the privilege of co-leading this effort alongside my f….

RT @broadinstitute: Using #AI, a Broad/@jacksonlab /@YaleMed team has developed a way to decipher the language of genetic switches that tur….

RT @YaleGenetics: 🔥🔥🔥 new paper out from Steven Reilly @ReillyLikesIt together with Ryan Tewhey @r_tewhey led by Sager Gosai @SagerGosai +….

Fantastic scMPRA approach from @jb_lalanne, @SRegalad0 & @JShendure. Lots of great observations buried in the supplemental too!.

RT @jb_lalanne: After a constructive set of reviews, our single-cell reporter work is OUT Check out the briefing if….

RT @jtung5: Two excellent sets of take-home impressions from @s_ramach and @ewanbirney on #BoG24. I'm going home excited and inspired by th….

Finally, we thank the @genome_gov for support. This work was funded by@ENCODE_NIH and data was released last year at @EncodeDCC. The project also allowed us to refine our MPRA protocol which we hope other groups will find useful for their own work.

@jacksonlab @ReillyLikesIt @LaylaSiraj @julirsch Data generation was the product of hard work and the expert hands of @KalesSusan, Danial (not on twitter) and @kousuke_mouri. We hope the data they produced will be valuable for many other projects going forward.

This was the first project we undertook when I started at @jacksonlab in Bar Harbor and a wonderful collaboration between the labs of @ReillyLikesIt and Hilary Finucane. Importantly, it was only made possible due to the careful work and brilliance of @LaylaSiraj and @julirsch.

I am delighted to see our work studying GWAS and eQTL causal alleles out in the wild. We learned several insights into how non-coding variation impart their effects. See Layla and Jacob’s tweetorial below for details.

RT @fuxmanlab: Had a great time hanging out with the @TewheyLab ! Thanks @r_tewhey and @jacksonlab for hosting us!

RT @anshulkundaje: This is by far the most convincing regulatory DNA synthetic design paper to date. Congrats to the authors 1/.

RT @niketa_n: Thank you!!! Honored to be a Tufts GSBS Rosenberg Fellow 🥳 Grateful for the nomination from my program and the endless suppor….

@jacksonlab @YaleMed @broadinstitute @i_rodcast @TewheyLab @SagerGosai @sabeti_lab @ReillyLikesIt Fun fact: The spark for this project came from experiments conducted by Natalia Fuentes during her summer stint in the @JAX_Education Summer Student Program. In 10 weeks she learned MPRA and produced amazing data that encouraged us to fully commit to this endeavor.

@jacksonlab @YaleMed @broadinstitute Shout out to @i_rodcast the brilliant computational scientist in the @TewheyLab who co-lead this project alongside @SagerGosai, and members of the @TewheyLab, @sabeti_lab & @ReillyLikesIt Lab for their help and support.

Five years ago, we wondered if we could design and validate synthetic, cell type-specific cis-regulatory elements that surpassed natural sequences. We are excited to share our successful approach, a result of a fantastic collaboration between @jacksonlab @YaleMed @broadinstitute.

RT @dsjpark: Excited to share our updated HiDRO paper in @nature We used HiDRO to screen for druggable regulators….

RT @julirsch: Very excited to see our work on using gene features to identify target GWAS genes out at @NatureGenet.