Tewhey Lab
@TewheyLab
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Identifying the precise genetic mechanisms influencing human complex traits and disease risk at the @JacksonLab 🧬🐭💻✨ (tweets from students and post docs)
The Jackson Laboratory, ME
Joined August 2022
I know you thought it was just another Thursday but SURPRISE! The Tewhey Lab is officially on Twitter!!! 🥳 Watch this space for science, lab and other fun updates from @r_tewhey's lab ⬇️
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RT @jacksonlab: @MaineCalling's Patty Wight spoke with JAX researcher Ryan Tewhey (@TewheyLab) regarding his recent publication in @Nature.….
mainepublic.org
The team has developed synthetic 'DNA switches' that can control genes in certain cells. It's believed the technology could ultimately be used to treat diseases such as Alzheimers and diabetes.
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RT @i_rodcast: Excited to share our sequence design work published in @Nature. I had the privilege of co-leading this effort alongside my f….
nature.com
Nature - A generalizable framework to prospectively engineer cis-regulatory elements from massively parallel reporter assay models can be used to write fit-for-purpose regulatory code.
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RT @SagerGosai: I’m thrilled to share that our paper “Machine-guided design of cell-type-targeting cis-regulatory elements” was published o….
nature.com
Nature - A generalizable framework to prospectively engineer cis-regulatory elements from massively parallel reporter assay models can be used to write fit-for-purpose regulatory code.
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RT @broadinstitute: Using #AI, a Broad/@jacksonlab /@YaleMed team has developed a way to decipher the language of genetic switches that tur….
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Happy National Postdoc Appreciation Week to Tewhey Lab post-doc @takeshi_iwasaki!! 🥳🎉 Takeshi is studying regulatory variants in autoimmune disease and is actually this year’s @jacksonlab JAX scholar!!🏆🧬 #NPAW2024
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Yes Takeshi!!!! JAX Scholar and Tewhey Lab post doc @takeshi_iwasaki talks about his work in the lab ⬇️🧬.
2024 JAX Scholar @takeshi_iwasaki discusses his work in the @TewheyLab identifying #genomicvariants and genetic mechanisms that influence #autoimmunedisease, and the importance of linking genetic variants to disease presentation or risk:
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RT @jacksonlab: 2024 JAX Scholar @takeshi_iwasaki discusses his work in the @TewheyLab identifying #genomicvariants and genetic mechanisms….
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RT @LaylaSiraj: Could not be more delighted to present our work investigating how over 220,000 complex and molecular trait-associated genet….
biorxiv.org
Identifying the causal variants and mechanisms that drive complex traits and diseases remains a core problem in human genetics. The majority of these variants have individually weak effects and lie...
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RT @jacksonlab: #Postdoc job of the week: Join the @r_tewhey @TewheyLab to use novel, high-throughput techniques to study genetic mechanism….
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RT @anshulkundaje: This is by far the most convincing regulatory DNA synthetic design paper to date. Congrats to the authors 1/.
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RT @ReillyLikesIt: SO happy this is live! See @SagerGosai tweet explaining our amazing collab with @i_rodcast, @r_tewhey, @PardisSabeti!. T….
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RT @niketa_n: Thank you!!! Honored to be a Tufts GSBS Rosenberg Fellow 🥳 Grateful for the nomination from my program and the endless suppor….
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RT @SagerGosai: I’m excited to share some work I co-lead with @i_rodcast and spanned the labs of @PardisSabeti, @ReillyLikesIt, and @r_tewh….
biorxiv.org
Cis -regulatory elements (CREs) control gene expression, orchestrating tissue identity, developmental timing, and stimulus responses, which collectively define the thousands of unique cell types in...
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RT @niketa_n: It’s official, the Twitter bio has been changed - ya girl’s a PhD candidate! 🥳 Grateful for all the support from my friends,….
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RT @jacksonlab: New in @ScienceMagazine, JAX's @r_tewhey @TewheyLab & colleagues I.D. 800 human-specific conserved deletions (hCONDELS) tha….
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RT @jacksonlab: New in @ScienceMagazine, JAX's @r_tewhey @TewheyLab & colleagues I.D. 800 human-specific conserved deletions (hCONDELS) tha….
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Getting emotional about friendship and an ice bucket on a Thursday. 🥲🧊.
@r_tewhey @TewheyLab the ice bucket, from corning, is truly an ELITE ice bucket. It's the Rolls Royce of ice buckets. The kind you get an unhealthy obsession with during your post doc, and won't buy for your own lab. Until your amazing friend buys one for you :).
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RT @jacksonlab: #Postdoc job of the week: Join the @r_tewhey @TewheyLab to use novel, high-throughput techniques to study genetic mechanism….
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Congratulations!! Kousuke's talk at @IMGC2023_sec was based on his paper on genetic variants of regulatory elements in autoimmune disease. Read Kousuke's BACH2 paper here:
nature.com
Nature Genetics - Integrating methods that assess allele-specific regulatory activity and chromatin accessibility in T cells identifies putative causal variants for five autoimmune diseases.
Thank you so much @IMGC2023_sec for selecting my talk as an outstanding presentation. It is a great honor!
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