Nico Franzmeier
@nfranzme
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Neuroimaging Researcher | LMU Munich | Institute for Stroke and Dementia Research | studying tau in Alzheimer's disease and 4R tauopathies @nfranzme.bsky.social
München, Bayern
Joined February 2017
Excited to share our new work in Molecular Neurodegeneration, showing that α-synuclein co-pathology is common in Alzheimer’s and accelerates amyloid-related tau accumulation, supporting its role as a tau co-aggregation factor.
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RT @bttyeo: 1/11 Excited to share our @Naturestudy led by @Leon_Oo1 @csabaorban @ZShaoshi. It is well-known that A….
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Many thanks to co-senior author @matbrendel as well as @JGnorich, @SebRoemer, Carla Palleis, @AnnaDewenter, @AnnaSteward_, @davinabiel, @johanneslevin, Günter Höglinger and many others!.
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The study was motivated by cerebellar 4R tau in PSP potentially confounding conventional cerebellar tau-PET reference regions. Using a data driven approach, we identified temporo-orbital white matter as a suitable reference that may support the biomarker workup in 4R tauopathies.
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Very happy to share our 2nd paper today, led by Lukas Frontzkowski: We developed a novel data driven reference region for PI-2620 PET tailored to assess 4R tauopathies, improving i) PSP vs. control separation and ii) PET associations with clinical scores.
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Many thanks to co-senior author Günter Höglinger, @matbrendel, @SebRoemer, @M_Malpetti, @JGnorich, @johanneslevin and many others!.
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Happy to share new work by Carla Palleis in @movedisorder, showing that brain networks route neurodegeneration patterns in PSP.=> This suggests that grey matter atrophy expands across connected brain regions, potentially following tau accumulation in PSP.
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RT @PaquetLab: Open #Postdoc position @isd_research @LMU_Muenchen to develop an #iPSC-derived #BBB model. Fully funded and embedded in our….
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Highly recommended PhD opportunity! Great supervisor, great datasets, very innovative methods and tools to understand the complex mechanisms of AD. Downside: you need to be really smart to understand all their work ;).
‼️PhD Position now available in my lab‼️ . Do you like:.* Neurodegenerative disease?.* Neuroimaging and/or multi-omics?.* AI and data-driven life science?. Want to work with @RikOssenkoppele Alexandra Young and Laura Wisse?. Apply here: Please rt/share 🙏.
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Congrats Hamilton, very happy to be part of this great work!.
I am excited to present our new study out in @NatureMedicine where we discover a novel synaptic protein biomarker to predict if and when someone will get Alzheimer’s disease dementia. Part 2/3 from my PhD work in the @wysscoray lab. 🧵1/12. Full study 🔗:
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RT @neuroprinciples: RT appreciated: We have a fully funded PhD position in @CompNeuro_lab (at TU Dresden). You can use .
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RT @JanBroderEngler: The #tidyplots paper is now published in @iMetaScience 🎉🥳🔥. Whenever you use tidyplots in your published work, conside….
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RT @MolNeuro: 'Alpha #synuclein co-pathology is associated with accelerated #amyloid-driven tau accumulation in #AlzheimersDisease'. Nicola….
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RT @MasudHusain: Why academia is sleepwalking into self-destruction. My editorial @Brain1878 If you agree with the sentiments please RT. I….
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Quite sad to re read this after only a few months. Meanwhile the US government is actively eliminating scientific freedom and publicly bullying leaders of a country attacked by a ruthless aggressor…didn’t expect things to go so wrong… #idiocracy happening….
For my fellow US-based researchers: Europe is a very nice place to work, where our leaders aren't orange and don't promote cage fights among immigrants. Sounds interesting?. Come work with us!.
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The X algorithm is insane. I am not following any political account but my timeline is full of extreme right wing bullshit posts from people I have never heard of. This is Elon musks influence on the German elections. It is incredible how this Bond villain manipulates the media.
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