MatthiasBrendel
@matbrendel
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Senior Physician | LMU Munich | Department of Nuclear Medicine | Molecular Neuroimaging of Neurodegenerative Disorders
München, Bayern
Joined August 2020
RT @MolNeuro: 'Alpha #synuclein co-pathology is associated with accelerated #amyloid-driven tau accumulation in #AlzheimersDisease'. Nicola….
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RT @nfranzme: Incredibly happy and proud to share our newest work in @ScienceTM showing that Aβ promotes neuronal hyperconnectivity, thereb….
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RT @nfranzme: Happy to share @davinabiel newest in @EmboMolMed showing stronger Aβ-dependent p-tau increases in women, potentially driven b….
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RT @davinabiel: Check out our new work where we show that female sex is associated with a stronger Aβ-dependent p-tau secretion, potentiall….
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RT @nfranzme: Happy to share our new work led by @JGnorich and @matbrendel, suggesting a visual read algorithm for PI-2620 in 4R taupathies….
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RT @nfranzme: Massive team effort across facilities at @LMU_Muenchen and @SyNergy_Cluster. Many thanks to @matbrendel, @GunterHoglinger, Jo….
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RT @nfranzme: Looking up all ~550 cases that we saw over ~10 years in our memory clinics, with both CSF and Aβ-PET obtained in clinical rou….
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RT @RikOssenkoppele: Pleased to present the design paper of a Dutch multicenter study in which we aim to assess the clinical value of Tau P….
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🚨 Just out in Theranostics: ☢️ we developed a new microglia specific Cu64-labeled TREM2-PET radiotracer ☢️ importantly this antibody based tracer has an integrated brain shuttle system (hTfR) to cross the blood-brain barrier. #Theranostics.
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RT @nfranzme: Very happy to share our new work out in @alzdemjournals, showing that combining PI-2620 tau-PET and fluid p-tau markers can h….
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Strong translational collaboration within our TSPO research unit by @LauraMBartos @ProfNAlbert @ilginkolabas @erturklab @ArtemZatcepin @nfranzme and many more!.
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Just out in @CCR_AACR 🚨Remote neuroinflammation matters in glioblastoma! Using TSPO PET in patients and cellular tracer allocation in mice, we show that microglia activation in the contralateral hemisphere associates with short survival.
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RT @MolNeuro: 'Regional desynchronization of #microglial activity is associated with cognitive decline in #AlzheimersDisease'. Artem Zatcep….
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RT @RoemerSeb: Happy to be part of this cool cooperative project between Cambridge @M_Malpetti and the Munich 4R tauopathy team lead by @nf….
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RT @nfranzme: Excited to share our newest work showing that neuroinflammation parallels tau spread in 4R tauopathies, suggesting a key role….
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Biological definition of Parkinson’s disease is approaching 🚀 will this be „ATN“ for PD? much to do for the neuroimaging community! Many thanks to @SilviaMorbelli @ProfNAlbert @GunterHoglinger and the EANM NIC!.
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RT @nfranzme: Super happy to share our new work in @Brain1878 by @RoemerSeb and @matbrendel:.in 4R tauopathy patients, we show that subcort….
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RT @RoemerSeb: So happy about this paper and all thanks to the help of @matbrendel and our amazing lab and it’s PI @nfranzme, as well as al….
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🚨publication alert: image derived input function for [18F]PI-2620 quantification. An elegant way to perform kinetic modeling before selecting an appropriate reference tissue. Many thanks to @nfranzme @GunterHoglinger @JGnorich @johanneslevin @RoemerSeb .
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Thrilled to share our new Preprint on the cellular origin of PI-2620 in 4R tauopathies, including PET to autopsy data animal models, cell-sorting and much more. Key message: PI-2620 does capture 4R tau. Thanks to @matbrendel @GunterHoglinger and many more!.
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