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@iMetaScience

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A Wiley partner journal aims to promote metagenomics and bioinformatics by publishing research articles, reproducible methods, protocols, and reviews.

Groningen, the Netherlands
Joined December 2021
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@iMetaScience
iMeta
2 months
πŸ€” Curious what #iMeta is and why we reached IF = 33.2 in just 3 years? πŸš€ ⚑Wondering how we process manuscripts so fast while driving cutting-edge discoveries? πŸŽ₯ Watch this short video β€” the answers are here. More details about iMeta: https://t.co/wzLbm1Gw7W #Bioinformatics
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@iMetaScience
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11 days
🌸 Profiles 6423 Chinese women and uncovers a midlife shift in the #vaginal #microbiotaβ€” βš–οΈ Decline of #Lactobacillus crispatus, rise of #Gardnerella vaginalis around age 40. 🧠 A new #microbiome balance score predicts reproductive health risks. πŸ”— https://t.co/OHjM6nwqxr
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onlinelibrary.wiley.com
The vaginal microbiome is central to reproductive health, yet large-scale studies in East Asian populations remain scarce. Here, we characterized the vaginal microbiota of 6423 Chinese women of...
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@iMetaScience
iMeta
11 days
🧬 CycloneSEQ #nanopore sequencing rapidly reconstructs multidrug-resistant bacterial genomes! βš™οΈ 96.16% read accuracy, 99.98% assembly accuracy. πŸ’‘ Complete genomes with just 15Γ— long reads or 5Γ— hybrid data. πŸ”— https://t.co/adbchn4puT #Bioinformatics #BGI
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Multidrug-resistant (MDR) bacteria commonly harbor highly complex genomes enriched with mobile elements and resistance islands, which are challenging to resolve using short-read sequencing. Here, we...
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@iMetaScience
iMeta
11 days
🐭 #Lactiplantibacillus plantarum Hi188 promotes post-weaning growth in mice. πŸ§ͺ The #metabolite 5-HIAA activates hepatic #AhR, boosting IGF-1 production. πŸ§‘β€πŸ’» Multi-omics data reveal that 5-HIAA is co-produced by the host–microbiota axis. πŸ”— https://t.co/ZxhLwviRzg #microbiome
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This study discovered that Lactiplantibacillus plantarum Hi188 promoted linear growth in postweaning mice. Transcriptomic analysis, untargeted metabolomics, and in vitro experiments showed that the...
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@iMetaScience
iMeta
14 days
πŸΆπŸ’© Humans and dogs share more than companionship β€” their gut microbes evolve together! 🧬 Dogs’ gut microbiomes show greater functional similarity to humans than macaques do. πŸ”— https://t.co/fnqlsJzw8R #microbiome #metabolism
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@iMetaScience
iMeta
14 days
πŸ€– #AI is reshaping anti-infective #drug development! πŸ’‘ AI accelerates discovery, optimizes lead compounds. βš•οΈ AI empowers rapid pathogen resistance prediction, outbreak response, and drug repurposing. πŸ”— https://t.co/QXjZrkHsSj #antibiotics
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onlinelibrary.wiley.com
Artificial intelligence (AI) technology is revolutionizing antimicrobial drug development. In response to increasingly severe antimicrobial resistance challenges, AI can efficiently predict pathogen...
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@iMetaScience
iMeta
19 days
πŸ’‘ 30 scientific recommendations from the #CHINAGUT Conference! πŸ‘©β€πŸ”¬ 63 experts joined forces to shape the future of: 🦠 #Probiotics πŸ’Š Live biotherapeutic products πŸ’© #FMT The goal: standardization, regulation & precision in #microbiome-based therapies. πŸ”— https://t.co/L2noJTen1B
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@iMetaScience
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19 days
🧬 #Multiomics analyses reveal PRMT5 as a key regulator in white #adipocytes! ⬇️ Prmt5 knockout downregulates genes for #FA uptake, #TG synthesis & oxidation ⬆️ Upregulates genes for #glucose transport, #glycolysis, peroxisomes & #cholesterol biosynthesis link:
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@iMetaScience
iMeta
19 days
🌿 New study deciphers Atractylodes lancea chemotype differentiation. 🧬 Genetic divergence aligns with altitude & climate gradients. πŸ’‘ But chemotype variation is co-shaped by soil nutrients and #microbiota. 🦠 Core #rhizosphere & endophytic microbes drive metabolic
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@iMetaScience
iMeta
20 days
πŸ«€ Stigmasterol attenuates #atherosclerosis by targeting #inflammation and foam cell formation. πŸ“Š #scRNA-seq reveals decreased inflammatory macrophages and SMC-derived intermediates in ApoE⁻/⁻ mice. 🧬 Stigmasterol enhances cholesterol efflux, suppresses ox-LDL uptake, and
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@iMetaScience
iMeta
20 days
🧬 New insights into the diversity of #CRISPR–Cas systems! #Metagenomic analyses uncovered 4,112 Cas12 proteins and 6 novel subtypes with distinct features. πŸ’» #AI-based Cas12fam annotates 18 domains. πŸ”¬ Conserved glycines in RuvC-I/II are crucial for dsDNA cleavage. 🌿 #Cas12
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@iMetaScience
iMeta
20 days
πŸŽ‰ #iMeta is reshaping academic communication! πŸ’‘ By integrating multiple social media platforms and adopting a bilingual model, iMeta boosts global sharing and collaboration. πŸ“Š Over 1.36M downloads, 10K citations, and an IF of 33.2 in 2024! 🧩 Sub-journals (#iMetaOmics,
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@iMetaScience
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22 days
Tumor electrophysiology drives malignancy through membrane potential shifts & ion channel fingerprints πŸ’Š Targeting ion channels, applying #tumor-treating fields, and using nano-delivery systems form next-gen precision strategies 🧠 Electro-#immunotherapy reshapes the tumor
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@iMetaScience
iMeta
22 days
🧬 14 spatial clustering methods benchmarked across ~600 #SpatialTranscriptomics datasets πŸ’» Covering 10 technologies & 8 organs πŸ“Š Reveals how data traits & spatial patterns shape accuracy βš™οΈ Recommends optimal preprocessing & method selection πŸ”— https://t.co/zRaUpibZe9
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@iMetaScience
iMeta
22 days
🌏 New study: #Soil #pH modulates microbial #nitrogen allocation across Japanese forests 🌲 πŸ§ͺ Acidic soils host stress-tolerant microbes that retain nitrogen βš™οΈ Near-neutral soils favor energy-efficient taxa that release #ammonium and drive #nitrification πŸ”„ #Microbial
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This study reveals how soil pH regulates microbial N allocation in forest soils across Japan. We show that microbial abundance controls the overall rate of N cycling, while microbial composition and...
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@iMetaScience
iMeta
1 month
πŸ‘πŸ‘πŸ‘ Congratulations!!
@jingyuan_fu
Jingyuan Fu
1 month
Ik voel me vereerd om KNAW-lid te worden. De installatieceremonie was fantastisch. Dank aan iedereen die er was om mij te steunen. @wijmenga_cisca @SashaZhernakova @knoers @McintyreGenEd Jackie Senior, Folkert Kuipers, and Vivian. Thank all of you
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@iMetaScience
iMeta
2 months
🧩 New insights into the #gut–#brain axis: 🦠L-lysine boosts barrier function & eases anxiety via tryptophan metabolism 😟H. biformis strengthens the barrier but worsens #anxiety πŸ’»Multi-omics reveal lysine degradation as a key mechanism πŸ”— https://t.co/zS4Bhnr1Fz #microbiome
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