
Jake Vogel
@_JakeVogel_
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Neuroimaging guy, Philadelphia sports fan, beer, open science.
Philadelphia, PA
Joined February 2019
‼️New preprint‼️ Super excited to share this work by the incredible @anlijuncn. We explore the potential of plasma proteomics and AI for neurodegenerative disease (AD, PD, ALS, FTD,CVD) diagnosis in a massive dataset (N>17,000). Paper link and walkthrough in Lijun's 🧵 below!
Can AI reveal the risk and co-pathology of multiple neurodegenerative diseases from just a single blood sample? We explored the AI-based diagnostic power on a massive sample (N=17,170) and high-rank plasma proteomics data. https://t.co/kgBbWGVWAP
#MedSky #neuroskyence #neurosky
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We have multiple openings for PhD candidates and postdoc positions: https://t.co/NiNK3LxvBD!
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The effect of spherical projections on spin tests for brain maps | https://t.co/NAkXjsO9Jo Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @VinceBazz explores ⤵️
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I’m running to become the 1st person from Morocco to go to Space–together with @seraspaceage and @blueorigin 🚀🇲🇦🌍 Support my journey! Create your own SERA Space profile on Telegram thru my referral link here: https://t.co/pBPR6JezLK
#SERAspace
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We are excited to launch The Data Quartet Challenge, recognizing student contributions to projects that integrate data from at least 2 of 4 FRQ supported Quebec Alzheimer’s and Aging cohorts (PREVENT-AD, CIMA-Q, NuAge, TRIAD), with 3 prizes of 5000$ https://t.co/jUYizVxi2u
drive.google.com
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In our new study @NatureComms, Dr Soares et al show that CSF total tau, often used as a marker of neurodegeneration, is more strongly linked to synaptic degeneration than axonal or neuronal loss in Alzheimer’s disease. Check our paper here🔗 https://t.co/AP74CkgmsX
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Highly recommend getting a PhD - very rare to have the chance in your life to do truly open-ended, self-directed research surrounded by super smart, passionate people. You have the whole rest of your life to grind on applied work. Usual caveat of having a great professor to
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Large-scale cortical functional networks are organized in structured cycles | Nature Neuroscience https://t.co/cQBmNhpRBE
nature.com
Nature Neuroscience - The human brain cycles through a repertoire of brain networks on a 1-second timescale during rest and tasks. This cycling appears to allow periodic engagement of essential...
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Don’t miss ABC’s "Emma and Bruce Willis: The Unexpected Journey – A Diane Sawyer Special," airing Tuesday night, Aug. 26 at 8 p.m. PT. It explores Bruce Willis’ journey with FTD and features insights from UCSF’s Dr. Bruce Miller.
abc.com
Watch "Emma and Bruce Willis: The Unexpected Journey – A Diane Sawyer Special" Tuesday, Aug. 26 on ABC.
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📣 Call for Papers Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring Special Issue – Real-World Evidence on Amyloid-Targeted Treatments: Early Data on Clinical Implementation, Safety, and Efficacy Submission Deadline: December 31, 2025 Amyloid-targeting
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So excited to share our recent publication in Brain: https://t.co/O9yC0llfqS, in which we show that tau progression in atypical AD follows the brain’s intrinsic functional connectivity architecture, originating from local epicenters. @RikOssenkoppele @nfranzme @Colin__Groot
academic.oup.com
In a large, multicentre study using tau-PET and post-mortem data from individuals with five clinical variants of Alzheimer’s disease, de Bruin et al. show
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Great thread
I’m proud to share our systematic review & meta-analysis of plasma p-tau diagnostic accuracy studies :) https://t.co/zXOs1Yu6uF Some highlights:
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Our didactic review on machine learning for causal inference, now open access We explain • identifiability (theory of when the data can answer a causal question) • machine-learning estimators • study design (asking well-framed questions, and loopholes, eg with time-wise data)
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New paper with @NeuroRJ, @csinva, @SunaGuo, Gavin Mischler, Jianfeng Gao, & @NimaMesgarani: We use LLMs to generate VERY interpretable embeddings where each dimension corresponds to a scientific theory, & then use these embeddings to predict fMRI and ECoG. It WORKS!
Evaluating scientific theories as predictive models in language neuroscience https://t.co/Ao2f3WNXNN
#biorxiv_neursci
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🚨New paper alert! Methods & insights from the Health & Aging Brain Study – Health Disparities (HABS-HD) 🧠📊 We examine amyloid, tau, neurodegeneration, cognition & social determinants of health in Hispanic & NH Black & White older adults. ➡️ https://t.co/rBhKy04kJA
@USCLONI
alz-journals.onlinelibrary.wiley.com
INTRODUCTION The Health and Aging Brain Study–Health Disparities (HABS-HD) is an ongoing prospective study aimed at understanding brain health and aging. The current work provides a description of...
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Interested in Network hubs, cortical hierarchies, and gradients? Ever wonder where they come from? Check out our latest review, where we cover different approaches to mapping hubs, models for their evolution, and mechanisms for how they develop: https://t.co/it10kxSAee
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The Sudmant lab at UC Berkeley is seeking a postdoc to work on a fully funded NIH project to understand differences in DNA repair and somatic mutation across the primate tree of life. Please spread widely to those who may be interested
aprecruit.berkeley.edu
University of California, Berkeley is hiring. Apply now!
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All the paperwork linking Imaging Neuroscience into PubMed Central is now sorted. All papers (previous and new - 680 to date) are fully indexed: https://t.co/NMUXmnVq47
https://t.co/DMUVicDRBQ
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Hi! Excited to announce that the major work from my PhD is out now on biorxiv! (w. coauthors @kianzkermani , @allydworetsky , @nathanlabora , @joannajhern , @RodBraga , @DerekEvanNee , @GrattonCaterina + others) https://t.co/CFsPAADmFO (1/18)
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I still get chills Meet Mike *30+ years severe depression *first hospitalized @ 13y *20 meds *3 rounds of ECT *2 near-fatal suicide attempts Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE see paper, thread https://t.co/8bdB2pXxQa
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Mapping cerebral blood perfusion and its links to multi-scale brain organization across the human lifespan | https://t.co/pjI36Z7wLi How does blood perfusion map onto canonical features of brain structure and function? @AsaFarahani investigates @PLOSBiology ⤵️
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