Marc Duque Ramírez
@marcduque3
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NeuroPhD candidate @harvardmed. Interested in new neuromodulation techniques and molecular approaches to understand how the brain works.
Cambridge, MA
Joined May 2019
Our paper on ketamine’s effect on astrocytes and behavior is out in @NeuroCellPress , with Alex Chen, Eric Hsu, and colleagues @alexbchen , @EricT_Hsu , with the @EngertLab , Fishman, & Bergles labs https://t.co/GiJUhmUNhJ
cell.com
Duque et al. show that astroglial calcium is recruited at active-to-passive transitions during learned-helplessness-like assays in both zebrafish and mice and that a variety of antidepressant...
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BioFestival 2025: Zymo Lightning Talk and Poster Competition Winners Announced #LifeScience #BioFestival @RachelleGaudet @ZymoResearch @Harvard @HarvardGSAS @HSCRB @hseas @broadinstitute @harvardmed
https://t.co/glz02ii6s6
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Just out! “The astrocytic ensemble acts as a multiday trace to stabilize memory.” We identified astrocytic ensembles that link experiences across days to stabilize memory https://t.co/po9zIlZvPb. New astrocyte tools are openly available at Addgene: https://t.co/OXCmcYSleI. 1/8
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We used protein engineering to develop cocaine-gated ion channels. Our approach simplifies chemogenetic applications for cocaine addiction by having cocaine itself activate inhibitory and/or excitatory channels. Collaboration between @mikelides @BrainCaRMA
https://t.co/X4zUdhGUG2
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🐟 New research led by the Ahrens Lab reveals how astrocytes trigger a biochemical circuit that regulates neuronal activity in zebrafish, causing the fish to stop swimming when they aren’t getting anywhere – a behavior critical for survival. ➡️ https://t.co/ukLhAyfTZU
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Shoutout @marcduque3
Congratulations to the Rising Stars in Neuroscience – Class of 2025! This is one of my favorite events each year, and this year was no exception. Keep an eye on this incredible group of scientists—they’re doing amazing things!
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Congratulations to the Rising Stars in Neuroscience – Class of 2025! This is one of my favorite events each year, and this year was no exception. Keep an eye on this incredible group of scientists—they’re doing amazing things!
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Do we need to rethink near-death experiences? What’s really happening in the brain? NDEs might be a hardwired coping strategy: the dissociation, calmness, and detachment when facing death may actually be an evolutionarily protective response. For decades, people have asked me:
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New Stars in Neural Circuits: Astrocytes Guide Brain State Changes @alexbchen @marcduque3 @EngertLab @MishaAhrens @HarvardGSAS @Harvard @RachelleGaudet @harvardmed @HHMIJanelia
https://t.co/JRzmN3auGQ
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Check out @alexbchen's thesis work, along with the other astrocyte papers in this @ScienceMagazine issue! From flies to fish to mice - air, water and earth, the science is fire 🔥🧯
Excited to share that the astrocyte-centered half of my thesis work is now out @ScienceMagazine! With @MishaAhrens @marcduque3
https://t.co/QL4dMq7byo 1/8
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Finally, stay tuned for other part of my thesis work, covering all of the other non-astrocyte cells in the brain, called neurons! Fish connectome dropping hopefully before GTA VI
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Locus Coeruleus to Medial Prefrontal Cortex Noradrenergic Neural Circuit Modulates States of Consciousness during Sevoflurane Anesthesia in Mice
biorxiv.org
How exactly does general anesthesia achieve its effects? It is so widely used in surgeries and medical treatments to enhance comfort for nearly one hundred years, yet its precise mechanisms underly...
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Honored and excited to present my work at the Rising Stars in Neuroscience Symposium! Grateful to @EricJNestler, @SinaiBrain and @UUNeurobiology for this opportunity — can’t wait to share what I’ve been working on!
👏Congratulations to the #NestlerLab's @GylesTrevonn on being selected as a Rising Star in Neuroscience! On May 19👉DON'T MISS the Rising Stars in Neuroscience Symposium Presented by Department of Neurobiology @universityofutah. RSVP: https://t.co/Cqg94ntfrF or scan the QR code
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Interestingly, work by @marcduque3, @EricT_Hsu, and I has shown that the fast-acting antidepressant ketamine blunts astroglial responsiveness to norepinephrine ( https://t.co/YRHKHXvddn). It would be interesting to see if lateral habenula astrocytes are affected in similar ways!
cell.com
Duque et al. show that astroglial calcium is recruited at active-to-passive transitions during learned-helplessness-like assays in both zebrafish and mice and that a variety of antidepressant...
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A rare carnivorous caterpillar, previously unknown to biologists, stalks spiderwebs for food whilst dressed in the remains of its prey, researchers report in Science. This unique new species, dubbed the “bone collector,” is found only on a single mountainside on the Hawai’ian
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Thrilled to announce that my PhD work has been officially published in @Nature! https://t.co/DAktxeViIB 🧵🧵🧵🧵🧵🧵 1/8
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Why socialize when you can spend all afternoon anesthetized on your own couch. What could possibly go wrong with injectable ketamine delivered to your door.
Today is Mindbloom’s biggest launch in 4 years: At-Home *Injectable* Ketamine Therapy We’ve always known injectable ketamine is the safest, most effective option but we delayed rolling it out because we knew it would make it too easy for Big Pharma to attack us. Now, with the
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Mom fish says you are not going to the party until you are old enough😤
Should I stay or should I go?! New study by @BaierLab shows that in cichlid fish mother and larvae follow their own intrinsic schedules during brood care. This leads to the larvae leaving their home shell exactly 9 days after fertilization. Find out more:
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So cool! 🐠💡
Interesting new #zebrafish paper on light induced activity and cilia from @yaksi_emre @NathalieJuYa labs
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