Gad Getz Laboratory
@getz_lab
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Twitter Page for The Getz Lab @MGHCancerCenter and @broadinstitute | Computational genomics of #cancergenes
Cambridge, MA
Joined April 2019
In a new study, researchers from @MGHCancerCenter @broadinstitute and colleagues investigated why breast #cancer therapy tamoxifen may lead to higher risk of uterine cancer. Read more: https://t.co/Jdd6mt19c0
https://t.co/x4WaWEBOzI
@getz_lab
nature.com
Nature Genetics - Sequencing analysis of tamoxifen-associated uterine cancers and further in vivo analyses suggest that the drug tamoxifen can activate the PI3K pathway in the absence of oncogenic...
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On #WorldLungCancerDay, we focus on BSF-supported U.S.–Israel research tackling one of cancer’s toughest challenges: persister cells. Dr. Yaara Oren @TelAvivUni & Dr. Gad Getz @broadinstitute are uncovering how these elusive cells survive therapy - and how we might stop them.
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1/ 🧵Check out our new study in @NatureGenet, which examines how precancerous conditions (MGUS/SMM) evolve into Multiple Myeloma, and offers new computational methods to predict progression risk and model cancer evolution. https://t.co/IHnN87QKTk
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In a new study, researchers from @MGHCancerCenter and colleagues' 'cell line atlas' provides a crucial resource for developing therapies for biliary tract cancer. The study was published in @CD_AACR. Read more: https://t.co/kEnFLxmPEa
@getz_lab @DrFranVazquez
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Now online in @CD_AACR: Generation of a Biliary Tract Cancer Cell Line Atlas Identifies Molecular Subtypes and Therapeutic Targets - by @Vindhya_Vijay, Negin Karisani,@getz_lab, Nabeel Bardeesy, and colleagues https://t.co/WuDOQUg14x
@MGHCancerCenter @broadinstitute
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Excited to share our comprehensive cell line atlas for biliary tract cancer (BTC) in collab with Dr. Nabeel Bardeesy @MGHCancerCenter & @DrFranVazquez, and led by @Vindhya_Vijay & Negin Karisani! https://t.co/ifDaogY4zE
@CancerDepMap @CD_AACR Also see: https://t.co/6zvHg38On9
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Our paper on establishing targeted therapy for MM with 1q+ is online ahead of print in @BloodJournal! w/ Liz Lightbody, Mairead Reidy, @IrenemGhobrial @gaddyg & Salomon Manier! https://t.co/TyduhtJ9tW
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ABSTRACT SELECT: @TimCoorens from @getz_lab
@broadinstitute details novel technologies to detect somatic mutations across normal tissues at the 2025 @AGBT General Meeting. #AGBTGM
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Let's walk through what we found in our new study using single-cell RNA-seq on tumor and immune cells from pts w/ asymptomatic Waldenstrom's Macroglobulinemia - out now in @NatureComms! W/ @Yoshi_konnykid @IrenemGhobrial @gaddyg #wmsm #mmsm
https://t.co/1Q1yh2rL1c 1/
nature.com
Nature Communications - The impact of tumor intrinsic and immune alterations on disease progression in patients with Waldenstrom’s Macroglobulinemia (WM) remains to be characterized. Here,...
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Check out our new study using single-cell RNA-seq to characterize immune dysregulation and identify molecular subtypes in patients with asymptomatic Waldenstrom’s Macroglobulinemia! #wmsm W/ @Yoshi_konnykid , @IrenemGhobrial, @getz_lab @WMIWMF
https://t.co/1Q1yh2siQK
nature.com
Nature Communications - The impact of tumor intrinsic and immune alterations on disease progression in patients with Waldenstrom’s Macroglobulinemia (WM) remains to be characterized. Here,...
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Our new perspective article describing the human and non-human primate developmental GTEx projects is now out in @Nature! We outline the scope, vision, opportunities and challenges of these projects here: https://t.co/8T9otAvQTx
nature.com
Nature - The developmental Genotype-Tissue Expression (dGTEx) projects will catalogue and integrate gene expression, regulation and genetics data across 120 human donors from birth to adulthood...
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With @rheinbay_lab and additional Broad collaborators, we are excited to enter into this partnership with @Inocras to analyze whole genomes for the benefit of cancer research and cancer patients 🧬! @GenomeDoctor @BroadInstitute @MGHCancerCenter
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Congrats to @gaddyg and the other 5 amazing #broadies for being named today as Core Institute Members @broadinstitute!! 🎉
Six leading scientists and longtime members of the Broad community have been named as new core institute members at Broad: @getz_lab, @AnnaGreka, Nir Hacohen, @macosko, @bmneale, and @pardissabeti Congratulations to all! https://t.co/bYnMpmTrEL
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We thank Ofer Shoshani @ShoshaniOfer , Uri Ben-David @BenDavidLab and Yossi Yarden, Cancer Genome Structure & Dynamics meeting ( https://t.co/LuD9varfj0). It was a great meeting and it was nice to meet Gaddy Getz @gaddyg as well.
Excited for the Cancer Genome Structure & Dynamics meeting, taking place today at WIS. Co-organized by Yossi Yarden, Ofer Shoshani and myself, with Gaddy Getz and Paul Mischel as keynote speakers and a wonderful lineup of Israeli speakers. A great day of science ahead!
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Excited to present at #FOGBoston tomorrow on making @UltimaGenomics turnkey compatible with all existing downstream tools, with a real-world example leveraging methodology developed here in the @getz_lab to infer cancer phylogenies at resolutions not possible without #WGS.
#Sequencing is a pivotal topic at the heart of the Festival of Genomics & Biodata. Join us tomorrow at #FOGBoston for insightful talks and an expert sequencing panel that will delve into this topic. Don’t miss out—register now: https://t.co/nzxmc7tcdR
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We’re lucky to have you on our @getz_lab team, @lizd0m!! We are so proud of the breakthroughs you make in the lab AND on the water! 🧬🛶🥇 @broadinstitute #WhyIScience
“As someone who’s been rowing for a pretty long time, I think it’s really important to have a balance between two things that you find value in.” Learn how computational biologist @lizd0m juggles research and life as an elite rower in a #WhyIScience Q&A: https://t.co/YCCyPiwmXQ
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CONGRATULATIONS 🎉to the @getzlab and @lucapinello labs’ newest minted PhD, @vinyard_m, on successfully defending his thesis yesterday!! We are all so proud. @BroadInstitute @MGHCancerCenter @Harvard 🥂🥂🥂
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Our own @GeffenYifat is featured this month as the #NCIProteomics Spotlight on Early-Career Investigators Series for her wonderful work in the Clinical Proteomic Tumor Analysis Consortium #CPTAC 👏🎉! Check out her interview in the link below. @BroadInstitute @theNCI
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Congratulations to Gaddy and all of the new AACR Fellows, Class of 2024 🎉🥳!! @gaddyg
This evening, the 30 members of the 2024 class of AACR Fellows were inducted into the AACR Academy. The distinguished scientists who comprise the AACR Academy serve as a global brain trust, providing scientific leadership to advance the AACR's mission. #AACR24
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