Young Seok Ju
@GenomeDoctor
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Genome scientist working at KAIST, Korea. Publications available @ https://t.co/yXV87jI1Wc
Daejeon
Joined September 2011
I'm excited to share that our team at @inocras has posted our whole-genome analysis of 1,364 breast cancer cases—the largest cohort with clinical records to date. Many thanks to our collaborators at Samsung Medical Center and Seoul St. Mary's Hospital.
researchsquare.com
Recent advancements in genomic technologies have become critical tools for deciphering the genetic complexities of cancer tissues, enabling precision medicine strategies aimed at improving patient...
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RT @jogleeson_ucsd: Today I got to meet a hero of mine, Prof Eunjoon Kim (left) from @kaistpr and @IBS_media. I was lucky to mentor his for….
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RT @MobileGenomes: We had a great time in Barcelona in the 45th Frontier Scientists Workshop. Interesting topics and discussion on Genomics….
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RT @FranSupek: 🚀 ERC Starting Grants 2024 results are out!. Diving into the stats reveals insights on distribution of exciting science acro….
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RT @getz_lab: With @rheinbay_lab and additional Broad collaborators, we are excited to enter into this partnership with @Inocras to analyze….
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I am delighted that my company (@inocras) shows the utility of whole-genome sequencing in real-world oncology! A prospective study with Ajou Univ. Hospital.
nature.com
Experimental & Molecular Medicine - Personalized medicine customizes cancer treatment to each patient, using molecular profiling of tumors to find specific genetic changes that can guide...
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The paper is an extension of our observations from cancer:.(2014) (2020)
elifesciences.org
Identifying 1,907 mitochondrial somatic mutations from 1,675 tumor tissues provides new insights into the causes and effects of the mitochondrial genome mutations found in human cancers.
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Many thanks Peter Campbell for the construct discussion for its publication!.
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We are pleased that our analyses on somatic mitochondrial DNA mutations (mosaicism) in normal human cells are published! Great work @JisongAn.
nature.com
Nature Genetics - Analysis of 2,096 single-cell clones from three tissues of 31 healthy donors characterizes mitochondrial DNA mosaicism and highlights the following two origins of mtDNA variants:...
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We revealed the mutational signatures of ionizing radiation. The paper was just published at last….
cell.com
Youk, Kwon, Lim, Kim, Kim et al. used single-cell-resolution DNA sequencing to investigate the quantitative and qualitative impact of ionizing radiation (IR) on the mammalian genome. They found...
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RT @maxi_prep: NOW OUT @ScienceMagazine 🧬🐾🤓. “The evolution of two transmissible cancers in Tasmanian devils”. A 🧵 on our deep DNA sequenci….
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RT @EMBLEvents: 2024 is just around the corner and with it the 50th anniversary of EMBL! 🥳 Check out our updated 2024 Annual Poster and dis….
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We posted a preprint, "Mitochondrial DNA mosaicism in human normal somatic cells" We observed ~3 mtDNA mutations/cell, (2) the rate of new mutation acquisition over a lifetime, and (3) levels of heteroplasmies carried by the fertilized eggs. (@JisongAn).
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RT @timyu: Published online today. Congratulations to lead authors @jinkukkim, Sijae Woo, Claudio de Gusmao, and @zhaoboxun, and all of our….
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RT @Dan_Theodorescu: I’m very excited our @Nature paper is out! It is the first published evidence that loss of the Y #chromosome in #bladd….
cedars-sinai.org
As men age, some of their cells lose the very thing that makes them biological males—the Y chromosome—and this loss hampers the body’s ability to fight cancer, according to new research from Cedars...
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