Feyza Nur Arslan
@feyzanar
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cell biologist heavily exposed to mechanics, development, and synthetic biology | postdoc @OatesLab prev. PhD @HeisenbergCPLab BS @BilkentUniv
Lausanne, Switzerland
Joined July 2010
📣 Symposium 2050 at the University of Zurich Join us for this event exploring emerging directions in life sciences, presented by a diverse group of leading experts. Free and open to all! More info/register: https://t.co/PStH1Ob3Ya
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📢Exciting new work from the lab by @NMishra_bio et al, now out on @biorxivpreprint, reveals that the early embryo geometry spatiotemporally patterns zygotic genome activation (ZGA) in zebrafish.🐟 https://t.co/BfQxhxCAzw Have we piqued your interest? Read on to learn more... 👇
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I am very excited to share our most recent work on how ‘Cell heterogeneity and fate bistability drive tissue patterning during intestinal regeneration’ ☺️ Thanks a lot to @Silvia_Bar01 @d_brueckner @prisca @EdouardHannezo and all the co-authors!
A perfect start in the new year! 🌱 Regenerating tissues are just an amazing spatio temporal controlled process! Our new manuscript explores how cell heterogeneity and bistability orchestrate intestinal regeneration 🧵 https://t.co/TZaK4D2isb
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Membrane-tethered cadherin substrates reveal actin architecture at adherens junctions https://t.co/KD07Wc9ZHr
#biorxiv_cellbio
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Our study uncovering a new mode of how growth factors exert their effect on cell state via modulation of nuclear mechanophenotype is live - check it out! #mechanobiology #nucleus
How do #stemcells integrate information to make fate decisions? Check out our latest preprint where we find that growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to determine whether to retain or exit #pluripotency🧵👇 https://t.co/CB1vIDUFbX
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Stunning!
Ever wondered how stem cells ensure a balance between cell fates in the gut?⚖️Turns out, they’ve got rhythm!🎶Our latest research reveals that NOTCH-driven oscillations regulate stem/progenitor cell abundance and specify secretory subtypes. Check it out: https://t.co/qvEsbAbx5O
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📢Our paper on self-organized information in development is now out in @PNASNews! See below for a 🧵 on the preprint and check it out here👉 https://t.co/wObm1q0NEt
📢New preprint! Developmental systems have a remarkable ability to self-organize spatial patterns of different cell types. How can we quantify the information content & robustness of these self-organized patterns across biological systems? 👉 https://t.co/44GpDFNe7M
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PhD position in Mechanobiology in Marseille! Are you excited to study how mechanical forces impact the transcription of muscle nuclei as well as muscle metabolism? Join us at our fantastic campus in Marseille. https://t.co/zGdtbTdQTM
@Fly_EDS @IBDMmarseille @CNRSbiologie #muscle
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We are hiring PhD students to work on synthetic bottom-up reconstitutions in bacterial cell biology, with the focus on peptidoglycan/cytoskeleton cross-talk and role of bacterial glycans in cell-cell communication. Interested? Don´t hesitate to DM me!
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Thrilled to have this piece on the wonder, mystery, and very long history of #devbiol out in @aeonmag. https://t.co/iDGmoLPJtP
aeon.co
For 3,000 years, humans have struggled to understand the embryo. Now there is a revolution underway
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And the final version of this paper is now out on @Dev_journal! Sea star embryos and epithelial packing 😎
Our new paper is published today on @Dev_journal!!!! A collaboration with @DeirdreLyonsPhD and @Vane_Barone where we use sea star embryos to analyse the 3D packing dynamics and, of course, #sctuoids. This is the Thesis work of @aj_tagua. https://t.co/QvJa3p9xhN
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Want to know how human embryos start taking shape??? Check out the peer-reviewed version of our article on the mechanics of human embryo compaction @Nature
https://t.co/FwIulpZz4N You can also check the 🧵 from the preprint👇
BimBam!! We are thrilled to release our first study on the mechanics of human embryo morphogenesis! 🧵 @institut_curie @CNRS @virtual_embryo @cdf1530 @InstitutCochin @PslQlife @FRM_officiel @ag_biomedecine #HuDeCA @Inserm #IVF
https://t.co/SdD2UgTXps
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Still a few days to apply!
Our lab is looking for a zebrafish care technician (100% Univ Geneva Switzerland)! Feeding, animal and tank care, equipment maintenance, husbandry. Work directly with researchers and participate in experiments. Official training certificate is required
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Check out the peer-reviewed version of our study on the adhesion strengthening 💪during embryo compaction @BiophysJ After a swift and constructive peer review 👍, we've expanded our study of Cdh1 deficient contacts and added more statistical analyses. https://t.co/jVJx0q4S0L
cell.com
Compaction is the first morphogenetic movement of the eutherian mammals and involves a developmentally regulated adhesion process. Previous studies investigated cellular and mechanical aspects of...
30 nN !! That's how much stickier cells become after compaction. Check out the preprint from Ludmilla de Plater, our lab manager. https://t.co/gQPfGS6UZm
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Big thanks to @EpiMechFC for sharing my thread on cell-cell contact patterning! Have a look ⬇️
Cell-cell contacts orchestrate tissue assembly and diverse cellular interactions. 🎯But what mediates their intricate patterns?🤔 Join me, @feyzanar, in exploring the interplay of adhesion and subcellular mechanics in contact patterning.
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Conference alert! The first "Physics of cell fate decisions" conference will take place in May 2024 at @ISTAustria ! Exciting speakers at the interface of physics, information theory, dev/cell bio, and data science + many slots for contributed talks! Apply before April 22!
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Robust axis elongation by Nodal-dependent restriction of BMP signaling Read this Research Article by @alex_schauer_, Kornelija Pranjic-Ferscha, Robert Hauschild & @HeisenbergCPLab: https://t.co/QhANEvT7hN (🎥:Blastoderm and mesendoderm morphogenesis in wildtype explants)
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My PhD work is finally out @NaturePhysics!! We looked at the interplay between the cortex and cytoplasmic components to explore the role of friction forces in cellular morphogenesis. Many thanks to @HeisenbergCPLab, Raphaël Voituriez and Andrew Callan-Jones A thread (1/6)
A new study by @slv_caballero @HeisenbergCPLab @ISTAustria & colleagues, published in @NaturePhysics, shows how sea squirt oocytes harness friction forces within various compartments in their interior to undergo developmental changes after conception.
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