Alexandra Schauer
@alex_schauer_
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PhD student in Heisenberg lab @ISTAustria
Joined April 2020
My recent work with @genikhovich is now online as #preprint! I examined the mechanisms behind #BMP signaling in the secondary body axis patterning of the anthozoan cnidarian Nematostella (sea anemone). https://t.co/pORCmmmwtS Below a short teaser.
biorxiv.org
BMP signaling patterns secondary body axes throughout Bilateria and, strikingly, in the bilaterally symmetric corals and sea anemones – members of the bilaterian sister clade Cnidaria. It has been...
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Local and global changes in cell density induce reorganisation of 3D packing in a proliferating epithelium Read this #DevSIDiversity Article by @Vane_Barone, @aj_tagua, Jesus Andrés-San Román, @Hamdounlab, Juan Garrido-García, @LyonsLab_SIO & @lmescu: https://t.co/uj5vTdNa5y
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Fresh out of the press @Dev_Cell! w Z. Smith @YaleGenetics and B. Law & M. Chan @Princeton we engineer a high-content molecular recorder to reconstruct thousands of cell lineages during embryoid morphogenesis. #MeissnerLab @MPI_MolGen. A🧵(1/14) https://t.co/W4KEqZrE3c
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Cell-cell contacts orchestrate tissue assembly and diverse cellular interactions. 🎯But what mediates their intricate patterns?🤔 Join me, @feyzanar, in exploring the interplay of adhesion and subcellular mechanics in contact patterning.
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Scientists are looking at the signalling pathways involved in body axis formation in a sea anemone in the search for clues about its evolution. https://t.co/T0hT3LA0TE
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New @Dev_journal InPrints from @AshleyLibby12 & @t_rayon Summarising 3 recent preprints examining how glucose metabolism intersects with signalling during mammalian gastrulation https://t.co/ru4ESo3Pjq
journals.biologists.com
In recent years, metabolism has re-emerged as an active effector of physiological changes rather than a housekeeping process in development. Embryogenesis is underpinned by shifts in cellular energy...
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Conference alert! The first "Physics of cell fate decisions" conference will take place in May 2024 at @ISTAustria ! Exciting speakers at the interface of physics, information theory, dev/cell bio, and data science + many slots for contributed talks! Apply before April 22!
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Robust axis elongation by Nodal-dependent restriction of BMP signaling Read this Research Article by @alex_schauer_, Kornelija Pranjic-Ferscha, Robert Hauschild & @HeisenbergCPLab: https://t.co/QhANEvT7hN (🎥:Blastoderm and mesendoderm morphogenesis in wildtype explants)
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🙌What a start into the new year! Latest work by former PhD student @slv_caballero, showing how frictional forces mediated by cortical flows help shape the ascidian oocyte, is out in @NaturePhysics🎉 https://t.co/jRX6mCuioR Full🧵below for a sneak peak into the paper😁👇 Pls RT
nature.com
Nature Physics - Friction forces at the interface between tissues play a key role in tissue morphogenesis. Now friction at the cellular scale is shown to influence cell shape and cell rearrangements.
My PhD work is finally out @NaturePhysics!! We looked at the interplay between the cortex and cytoplasmic components to explore the role of friction forces in cellular morphogenesis. Many thanks to @HeisenbergCPLab, Raphaël Voituriez and Andrew Callan-Jones A thread (1/6)
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After a very fruitful revision @CurrentBiology, I am excited to present the final version of our paper at the end of the year🎄 @HeisenbergCPLab @nartimsoole @EdouardHannezo
https://t.co/ACqJCpul1o
cell.com
Arslan et al. show that the distribution of F-actin and E-cadherin at cell-cell contacts is achieved by a cortical actomyosin tension gradient along the contact radius, established by a combination...
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Are there multi-or pluripotent stem cells in anthozoans? This great work by #andreasdenner and other lab members shows that nanos2 is essential for the germline. Transgenic nos2+ cells give rise also to somatic cell types in #Nematostella:
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Stoked to share a new @teamstembryo preprint @mpicbg @PoLDresden📢. What drives phenotypic variation in embryo models? We discovered an important role for metabolism! https://t.co/mLDOFly250 Highly relevant: https://t.co/M1DvEvKtRn
@LabTrivedi @EbisuyaMiki Let 's eXplain (1/17)
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Check out our new preprint from first authors @steffi_lehr and @d_brueckner. Using a stencil system for neural progenitor differentiation, we observed striking biphasic BMP signalling dynamics and self-organized patterns and studied the mechanism. https://t.co/QQ9QgcqDHI
biorxiv.org
Developing tissues interpret dynamic changes in morphogen activity to generate cell type diversity. To quantitatively study BMP signalling dynamics in the vertebrate neural tube, we developed a new...
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Visualising the endogenous Fgf8a morphogen gradient Read this Research Highlight showcasing work from Rohit Krishnan Harish @rkharish93, Michael Brand and colleagues @CRTDpress @tudresden_de: https://t.co/Mib7Xq65ry
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@teamstembryo @mpicbg is hiring! We have an open position for a TA. #stembryos #gastruloids #stemcells combined with all kinds of imaging, omics, genetic/chemical/mechanical manipulations etc. Contact me for more info! And please RT https://t.co/D7IpiRqNz7
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My postdoc work is out on @biorxivpreprint
https://t.co/GCDXkj2zy2! I want to thank all the co-authors (present in the Twitter world @d_brueckner @SarenTasciyan @XinTong1996 @alex_schauer_ ) and all the friends and colleagues in @HeisenbergCPLab and @ISTAustria 🤩
biorxiv.org
Cell migration is a fundamental process during embryonic development. Most studies on cell migration in vivo have focussed on the migration of cells using the extracellular matrix (ECM) as their...
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Our lab is looking for a zebrafish care technician (60-100% Univ Geneva Switzerland)! Feeding, animal and tank care, equipment maintenance, husbandry. Work directly with researchers and participate in experiments. Official training certificate is required https://t.co/M4YK6tWumT
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📢 We are looking for a temporary, part- time technician to join our research group! 🐟🧬 Come be a part of our team @ISTAustria, on the outskirts of Vienna 😊 All details below, please use the link to apply 👇 Please RT!
ista.ac.at
Job details
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New #preprint on the #mechanics of the first folding event of the developing #zebrafish forebrain: https://t.co/9kpr4maGPC
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One month left to apply to this 4-year fully funded postdoc position in my group. We want to open a new research direction where we can predict drastic changes in tissue structure using machine learning! Apply here: https://t.co/o0z9aXcHEi And please RT ☺️
Very excited for this new collaboration with @AssafZaritsky - We are hiring!! 💥Not 1 but 2 fully funded 4-year postdoc positions! Are you interested in data science? Quantitative developmental biology? Machine learning? Rigidity phase transitions? Reach out and please RT!
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