🙏 A big thank you to the Liberali Lab, FMI community & the FAIM imaging platform for testing and giving valuable feedback - keeping ez_zarr sharp, fast & useful! (3/3)

From spatial sequencing data to 5D images & high-throughput plate screens, ez_zarr helps you navigate images & labels quickly. If you work with NGFF OME standards, give it a try — and let us know what features you’d like to see next 💡(2/3) 📚 Docs:

We’re excited to share that ez_zarr now supports Zarr v3! 🚀 Huge thanks to @mbstadler & Charlotte Soneson who took on the challenge of creating this open-source tool for fast, programmatic access to OME-Zarr file sets + easy plotting 📊 📄 https://t.co/urfYqDWAuR (1/3)

Check out our preprint on how initial cell-to-cell variability drives fate bistability and tissue patterning! 🧩 What a journey with @CSchwayer @d_brueckner @EdouardHannezo and @prisca!!

If you are attending #CellBio2024 and are interested in understanding how the process of crypt morphogenesis is coordinated both in vivo and in organoids then come to my talk Wed Dec 18th in the subgroup “Organoids as tools to study the function of tissue in Health and Disease”

At #ASCB2024 today to speak in the session "Accelerating Discoveries in Cell Biology Using AI" about our Cell Observatory initiative to expand our understanding of subcellular physiology in the native multicellular environment by coupling advanced 4D imaging with AI. We're

Join us in celebrating the launch of the Seattle Hub for Synthetic Biology with @AllenInstitute + @UWMedicine. 🎉 Led by @JShendure, this new collaboration will build tech to understand temporal dynamics of cells & whole organism perturbation ➡️ https://t.co/JbPIrkcKNO #SeaSynBio

In a departure from biological rhythms, we’re excited to share our work describing the role of macromolecular assembly & condensation in the acute buffering of cellular water potential, published today @Nature. A thread: 1/16 https://t.co/4UPHq7vXZ3

Happy to share new work from the Arber lab @FMIscience and @biozentrum done by Wuzhou Yang (inactive Twitter), me and Silvia Arber on a fine-grained map of the interaction between the cortex and medulla for the control of forelimb movements!

mutscan - a flexible R package for efficient end-to-end analysis of multiplexed assays of variant effect data https://t.co/GYlQH39N5g #biorxiv_bioinfo

Today, we and ⁦⁦@ganetzky1⁩ report ⁦@NEJM⁩ a remarkable case of twin boys with euthyroid hyper-metabolism (low body weight despite high caloric intake), due to a de novo mutation in mito CV that uncouples respiration from ATP synthesis.

This is a great honour for my Lab. This award shows that diversity and inclusion can be the path to reach excellent results. Thanks for all the support I received on the way. Follow your passions 🤩 https://t.co/XKkJkvWdSg

Cellular ionic content shows temporal variations that occur to balance soluble proteome @Oneill_Lab @Alestangh01 @MRC_LMB @CellBiol_MRCLMB https://t.co/I3zoToK8bY

Finally out the work of my amazing supervisor @Alestang01!!!💥 With the @ONeill_Lab we showed that circadian rhythms in molecular crowding drive daily Na/K rhythms, allowing heart cells to beat faster when the heart clock expects us to be up and active!

I am looking for a technical assistant to join me at @CECAD_ in Cologne. We will be working on the biology of circadian rhythms. Please RT. https://t.co/9bU9Ooqqyg

Once thought to only regulate walking, the brain’s mesencephalic locomotor region also controls many other body movements, researchers in the Arber group show. The findings, published in @CellCellPress, could help improve therapies for Parkinson’s disease👉 https://t.co/o9UcJBR252

Out now in @NatureCellBio: @QiutanYang, @priscaliberali & collabs @ISTAustria uncovered the forces that give the gut wall its classic brushlike appearance. The finding could help to reveal how the gut takes form and how this process goes awry in disease

The problem is not people being uneducated. The problem is that people are educated just enough to believe what they have been taught, and not educated enough to question anything from what they have been taught. 🧠

Function: Ligand combos are message “addressing” systems that can selectively activate different cell type(s) based on receptor expression. Outperforms 1-1 signaling arch. Works b/c ligand-receptor interactions “compute” complex responses.(Theory paper) https://t.co/CskiORBuHT

A very encouraging read. Thanks for your vulnerability, @AnneCharmantier. I resonate a lot with the tension of squaring personal life / health matters with professional ambition and aspirations (1/n):