Vinod BalachandranMD
@TheVinodLab
Followers
5K
Following
1K
Media
70
Statuses
780
Founding Director Olayan Center for Cancer Vaccines @MSKCancerCenter | Cancer Surgeon-Scientist | Pancreas cancer | Cancer immunology | 2x dad, 2x ironman
New York, NY
Joined June 2017
#mRNAvaccines for #PancreaticCancer (PDAC) PART4 1. Out today in @Nature
https://t.co/NhpkJeaQYb 🧵👇🏽 [1/23]
nature.com
Nature - In a phase 1 trial, patients with pancreatic ductal adenocarcinoma who were treated with surgery and bespoke neoantigen mRNA vaccines combined with anti-PD-L1 and chemotherapy exhibited...
110
806
4K
MSK physician-scientist Dr. Omar Abdel-Wahab (@AbdelWahablab), a leader in #bloodcancer research, has been named a 2025 Paul Marks Prize winner for his contributions to the field. Learn more about his path and what inspires his work: https://t.co/8Xc9oo3bVB
0
3
47
Over the last decade, computational oncologist Dr. @bengrbm has tried to shed light on the innate immune system and how it affects cancer cells as they evolve. One important aspect is a phenomenon called “viral mimicry,” caused by repetitive DNA sequences. Now Dr. Greenbaum’s
0
4
16
Thank you @MSKCancerCenter for highlighting our work on #viralmimicry in our genome, its evolution, the selective forces on it, and its potential role in cancer. A years long collaborative effort with @sunsiyu1 @stephen_martis @decarvalho_lab @petr_sulc & many great
Over the last decade, computational oncologist Dr. @bengrbm has tried to shed light on the innate immune system and how it affects cancer cells as they evolve. One important aspect is a phenomenon called “viral mimicry,” caused by repetitive DNA sequences. Now Dr. Greenbaum’s
0
1
16
Fascinating data and excellent presentation on PDAC RNA neoantigen vaccines by @TheVinodLab #ESMOGI25 full paper: https://t.co/ejDfVEKWgF
@Nature #ESMOAmbassadors
2
17
56
Excited to share our study describing a role for a subset of Thetis cells, TC IV, in tolerance to food antigens. A team effort led by Vanja Cabric and @YollandaPariso1 🧵 1/
science.org
In the intestine, peripherally induced regulatory T (pTreg) cells play an essential role in suppressing inflammatory responses to food proteins. However, the identity of the antigen-presenting cells...
11
20
88
Congratulations @themis_brown! Fantastic!!
Yet more brilliance from @themis_brown - its been a joy to have a front-row seat watching her group essentially rewrite the textbook on early life immunity. Kudos to one of the best scientists and human beings that I am fortuate to know! https://t.co/jlYKGahvfV
1
0
4
đź’ˇ Vinod Balachandran, Director of the Olayan Center for Cancer Vaccines at @MSKCancerCenter, will explain how mRNA vaccine technology is transforming cancer treatment.
1
2
7
Grateful & humbled to make the 2025 #TIME100HEALTH list with such inspiring global health leaders. This honor reflects my team, who are unrelenting in their efforts to advance new treatments for pancreatic cancer!
TIME's new cover: Meet this year's #TIME100Health, a community of leaders—scientists, doctors, advocates, educators, and policy-makers, among others—who are changing the health of the world. https://t.co/1MpFEK5mKo
9
10
90
MSK researchers are trying to understand how the immune system senses cancer in order to make better #immunotherapies. "If we can figure out generally what the immune system is sensing — and how it affects how cancers grow, spread, and adapt," says @bengrbm, a computational
1
7
34
A new mRNA vaccine could prevent pancreatic cancer from returning — potentially for the long haul. https://t.co/N5QJU1f04S
sciencenews.org
A vaccine kept patients free of pancreatic cancer for years, yet new reports say the NIH is advising against mentioning mRNA tech in grants.
41
193
596
I am moved by the passion and expertise of the remarkable team at the Olayan Center for Cancer Vaccines (Olayan CCV) and was excited to celebrate their continued work at the Olayan CCV Open House. The standing room-only event brought together @MSKCancerCenter cancer vaccine
0
7
54
Pancreatic cancer — a disease with a 90% mortality rate — has long been a grim diagnosis. But that may be changing. Meet Vinod Balachandran, the lead researcher behind a groundbreaking mRNA vaccine that’s transforming the outlook for patients. Credits : @RichardHanania
1
11
22
I had a fun time chatting with @DKThomp about cancer vaccines. Check it out.
New pod: The science of cancer vaccines Pancreatic is one of the deadliest cancers. In February, a New York lab found 75% of responders to its personalized mRNA cancer vaccine remained cancer-free at 3 years—a minor miracle. Today, Vinod Balachandran, the head of that lab,
3
3
34
We are incredibly grateful for the support of The Marcus Foundation. This generous grant marks the beginning of an exciting new partnership to discover and advance next-generation cancer vaccines – we are excited about the possibilities ahead!
The Marcus Foundation has awarded a generous grant to Dr. Vinod Balachandran (@TheVinodLab), Chief of the Olayan Center for Cancer Vaccines at MSK, to research next generation precision RNA vaccines for #pancreaticcancer. Learn more: https://t.co/4lvttPQ8Tj
1
2
57
A new paper shows that personalized pancreatic cancer vaccines can keep patients cancer-free for YEARS - an incredible outcome for a cancer with only a 7% 5-year survival rate.
36
370
2K
Great to chat with @scifri and @flichtman! Link to audio below.
In a small trial, nearly half of pancreatic cancer patients who received an mRNA vaccine had no signs of relapse after three years. Dr. Vinod Balachandran joins us to discuss the results and what they could mean for cancer treatment. https://t.co/jcdx865rBG
0
7
16
2-4pm est on local public radio - fun chat on cancer vaccines w @scifri @flichtman 👇🏾 https://t.co/1YjG1Zyr2R 🧵 👉🏾
sciencefriday.com
In a small trial, nearly half of pancreatic cancer patients who received an mRNA vaccine for the disease had no relapse three years later.
2
3
10
First, good news in the fight against #pancreaticcancer! ASPIRE awardee Ben Greenbaum (@bengrbm) of @MSKCancerCenter found that an mRNA neoantigen vaccine induces long-lived CD8+ T cells (potentially lasting decades!), which may delay recurrence.
nature.com
Nature - In a phase 1 trial, patients with pancreatic ductal adenocarcinoma who were treated with surgery and bespoke neoantigen mRNA vaccines combined with anti-PD-L1 and chemotherapy exhibited...
1
9
24
The same for a personalized neaontigen vaccine vs pancreatic cancer https://t.co/z0JEt2gyfS
@Nature
2
19
59
Nature research paper: RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer https://t.co/dHSd6ErLwP
nature.com
Nature - In a phase 1 trial, patients with pancreatic ductal adenocarcinoma who were treated with surgery and bespoke neoantigen mRNA vaccines combined with anti-PD-L1 and chemotherapy exhibited...
7
59
177