Daniel De Carvalho
@decarvalho_lab
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Scientist working on Cancer Epigenomics, Immunology, Liquid Biopsy, and Transposable Elements. Faculty @pmcancercentre and @UofTmedicine. Founder, https://t.co/FJYiJmIpBX
Toronto
Joined February 2014
Excited to have this paper out @Annals_Oncology with a concomitant oral presentation @myESMO #ESMO24 ! This is the culmination of our original cfMeDIP-seq work supported by @thePMCF into a clinical validation study for a tissue-agnostic MRD test in Head & Neck cancer.
📢@ESMO24 concomitant paper: Clinical validation of a tissue-agnostic genome-wide methylome enrichment MRD assay for head and neck malignancies. #ESMO24 #HeadandNeckCancer @adela_bio @UHN_Research @decarvalho_lab @ScottBratman
https://t.co/3zXRaa6deV
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Hear from 2025 Gairdner Momentum Award winner Dr. Daniel De Carvalho (@decarvalho_lab) @PMResearch_UHN on October 23 at @MaRSDD! Learn more about his impactful work in cancer epigenetics and his research journey here ➡️ https://t.co/ZcfLBK0jCk
#GairdnerAwards
uhnresearch.ca
Dr. Daniel De Carvalho wins 2025 Gairdner Momentum Award for advancing cancer detection.
Gairdner Science Week Laureate Lectures are back on October 23! Join us for this rare opportunity to hear directly from the 2025 #GairdnerAwards winners as they share the stories and science behind their discoveries. Register here ➡️ https://t.co/0VMOqOrYJX
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Share in the thrill of discovery! Gairdner Science Week is back October 20-23. Join us for a week of groundbreaking science with the world's top experts and #GairdnerAwards winners. Full event lineup and registration → https://t.co/jjmsovS5NJ
#GSW2025
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Are you currently in the ERE related field and want to find new collaborative opportunities? Join our Chairs @ChiappinelliLab, @shenhui1986, @twang5 & @paultaowu at the upcoming Endogenous Retrotransposable Elements & Human Diseases Conference this November! #EREHD25 🎙️Talk
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Don't forget to register for #EREHD25! Our talk submission deadline has been extended to 12 JUNE 2025, so submit your abstract today to join our incredible speaker line up in Mexico this November 🇲🇽 🔗 https://t.co/Ekcr6cYTOQ
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Europe pledges half a billion euros to lure scientists as Trump battles universities | Reuters
reuters.com
The European Union and France on Monday announced half a billion euros worth of incentives to lure scientists to the continent, seeking to profit from U.S. President Donald Trump's federal funding...
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They’re not just passive genomic elements—they’re active players that may hold the key to new therapies. Exciting to see the field gaining attention and momentum.
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Over the past decade, retroelements have become one of the hottest topics in biomedical science, shedding light on evolution, aging, cancer, autoimmunity, neurodegeneration, and more.
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Risky moves: Can blocking “jumping genes” treat diseases and aging? Great piece in Science Magazine highlighting recent efforts to understand and target transposons—also known as "jumping genes"—in human disease and aging.
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Thank you @GairdnerAwards! I'm truly humbled and grateful for this recognition. Science is never a solo journey and this award reflects the hard work, creativity, and persistence of many amazing scientists I had the privilege to work with.
Congratulations to the 2025 Canada Gairdner Award laureates! This year’s laureates represent some of the world’s most significant biomedical and global health research and discoveries. Find out more about these incredible scientists and their award-winning research here:
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Dr. De Carvalho is awarded “For the ground-breaking discovery of the role of transposable elements in regulating anti-tumour immunity through viral mimicry, which holds transformative potential for cancer therapy, and for pioneering the development of a novel blood-based test for
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From the April issue: Chronic #ViralMimicry Induction Following #p53 Loss Promotes Immune Evasion https://t.co/Tjb3Sf7ZC4 By @CharlesIshak @SajidMarhon @DeCarvalho_Lab and colleagues @UHN @pmcancercentre @MDAndersonNews
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Ever wonder why RNA and protein levels often don't match up? m6A RNA modification could be the missing link. Our work, the first m6A epitranscriptome map in prostate cancer, is out now in Nature Genetics! Huge thanks to collaborators+support from @PCFnews, @tfri_research &more
This RNA modification drives prostate cancer progression A study by @UHN & @UCLAHealthJCCC found m6A RNA modification promotes prostate tumour growth and relapse. It boosts the production of a cell movement molecule to aid cancer metastasis. @NatureGenet: https://t.co/TRV4hm21fL
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New Links: Cancer and Immune Evasion🧬 Recent study found that cancer cells without the tumour suppressor protein p53 become more resistant to the body's immune response. A study led by @decarvalho_lab at @UHN’s @pmcancercentre. https://t.co/COkgq1UuxM;
https://t.co/nLSoS26Agn
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Registration for #eshg2025 is now open. Register now and profit from early bird rates until April 10, 2025: https://t.co/aUBQh16piA Looking forward to welcoming you in Milan!
2025.eshg.org
Registration for ESHG 2025 is now open. The European Society of Human Genetics is planning the 2025 conference as a hybrid conference. This will allow attendees to participate in-person or online...
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Scientists @PMResearch_UHN have uncovered how cancer can evade immune defenses after losing a key tumour-suppressing gene. These findings implicate repetitive elements in DNA and may unlock new targets for cancer interception. Read more ➡️ https://t.co/zrjThGpQBz
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Normal and Abnormal Methylation Patterns and Detection: Ting Wang, Tommy Kaplan, and Daniel D. De Carvalho will address this topic in a plenary session at the #AACRmethylation25 Special Conference (February 1-4, San Diego). https://t.co/AInq6yIDJ7
@twang5 @decarvalho_lab
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We observers that we can interfere with this process, for example by blocking the reverse transcriptase activity of LINE1, suggesting a promising avenue for early cancer interception.
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