Stephen Martis
@stephen_martis
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Excited that this is out in @PNASNews !. In a sentence, we show that different mutational processes can have different long-term impacts on eco-evolutionary systems. 1/n.
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This was a really fun, organic collab with old friend Trevor GrandPre (@myphysicsvoyage) and David Schwab (twitterless, but @GC_CUNY). As a bonus for making it to the end, here's a fun pattern generated by this model that didn't make it into the manuscript. 5/n=5
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We show that this replicative mutation induced "trait-space patterning" (h/t @phsunny1 for coining the term afaik) is dependent on the precise details of the underlying population dynamics -- things like host-defense mechanisms tend to encourage patterning. 4/n.
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We couple these mutational processes to a relatively simple ecological model (a version of MacArthur's consumer-resource model) and show that replication coupled mutations can generate emergent phenotypic "clusters" while external mutagens do not. 3/n
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We break down mutational processes into two classes: 1. those due to external mutagens (think smoking or UV radiation) 2. those coupled to DNA replication (think error prone polymerases). 2/n
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RT @SantoshVardhana: #Preprint alert! Pioneering work by @tanmana_mitra sheds new insights into why T cells become metabolically exhausted….
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RT @SantoshVardhana: #Preprint alert! @KevinYTChen, a brilliant @GSKGradSchool graduate student and NCI F99/K00 awardee, identifies a nove….
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RT @myphysicsvoyage: Excited to join @WashUPhysics as an assistant professor in Fall 2025! My group will develop non-equilibrium statistica….
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RT @RShouval: 🚨 Just out @NatureMedicine!.Introducing InflaMix—a point-of-care tool that identifies an #inflammatory 🔥 signature predictive….
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RT @bengrbm: Our latest work on the #darkgenome is out now in @NatureComms. LINE-1 is the only known autonomous retrotransposon in our geno….
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RT @A_Zebboudj: I am thrilled to see our latest findings out in @Nature .-we identify that IL33 induces Tertiary Lymphoid structure via ILC….
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RT @TheVinodLab: 1. Tertiary Lymphoid Structures (TLSs) – on demand lymphoid aggregates that assemble in inflamed tissues/cancer to regulat….
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Fun project working with @myphysicsvoyage and David!. In a nutshell -- in eco-evo contexts, different types of mutational processes can drive different qualitative behavior, including pattern formation a la Turing. Check out the preprint if this sounds interesting to you!.
Thrilled to share our new preprint with Stephen Martis (@stephen_martis) and David Schwab (CUNY)! We show how the method of mutation drives eco-evolutionary dynamics, shaping trait-space patterning via nonreciprocal interactions. Just the beginning of exploring this rich model!.
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RT @HernanGGarcia: New preprint led by postdoc Brandon Schlomann discovering spatial patterns of immune response in fly larvae!. https://t.….
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RT @R_MoranTovar: The interplay between proliferating pathogens and the huge diversity of immune receptors, makes the problem of antigen re….
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RT @jrblundell: How do healthy tissues evolve to become cancerous? Delighted to share our latest research tracking the somatic evolution th….
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RT @EdReznik: Hello Xverse, we're on the hunt for a postdoctoral fellow to study cellular and systemic metabolism with a quantitative, mult….
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RT @ShoeStrapped: My student accepted a fully funded PhD in the US, but has had difficulty securing an appointment with the US consulate in….
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