Li Tang
@Tang_Lab_EPFL
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#Immunoengineering for better therapies | Associate Prof. of BioE @EPFL | Associate Editor @ESMO_IOTECH | Co-founder of @LemanBiotech
Lausanne, Switzerland
Joined May 2021
Thrilled to share our back-to-back two Nature @Nature papers on the unexpected role of type 2 immunity against cancer. We found that interleukin 4 (Fc–IL-4), a type 2 cytokine, reinvigorates exhausted T cells to potentiate anticancer immunotherapy w/ @YugangGUO2 @RongFan8(1/11)
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RT @XuZhouLab: Beyond excited to share our #NewPaper in @CellCellPress! Inflamed environments acidify intracellular pH. BRD4 senses this vi….
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The Yin-Yang of metabolic modulation for improving cancer immunotherapy - check our most recent review article on metabolic immunoengineering! Kudos to my former postdoc Bing Feng, now PI at Hangzhou Inst of Medicine, and PhD students Rongrong @RRLi11606739 and Weilin @Weiliin_L.
Feng et al. discuss the metabolic characteristics of tumor-infiltrating lymphocytes and innovative metabolic immunoengineering approaches to improve cancer treatment outcomes @Tang_Lab_EPFL
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RT @CPMM2424: We are excited to kick off our Forces at Play: Molecular Mechanobiology Seminar Series with Dr. Cheng Zhu from the Georgia In….
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Many congratulations to Michele! @Materials_EPFL @MicheleCeriotti.
Congratulations to @MicheleCeriotti for delivering his E. Bright Wilson Prize Lecture on machine learning for chemistry at @HarvardCCB! #chemtwitter.
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RT @CanAztekin: Interested in working with 🐸, 🐭, stem cells, or computational methods 🖥️ to delve into the unknowns of regeneration in our….
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Beautiful illustration of E-CAR T cell👍A new way to engineer CAR T cells. Congrats, Chenqi, Haopeng, and the team👏.
Glad to share our new publication @ImmunityCP , reporting a new E-CAR that can form mature immunological synapse through phase separation. Paper link:
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RT @GioeleLaManno: Interested in #singlecell and #spatial #metabolomics ? Then book your calendar for December 10th! – Our online, free ev….
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RT @PatrickHwuMD: #ScienceSaturday . ❓ How can we enhance CAR-T cell activity against solid cancers? . ➡️ In a recent study, Zhao et al tra….
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This cover art was based on real TEM images of mitochondria of exhausted CAR-T cells reinvigorated by IL-10. Kudos to Yiling Li, a PhD student of my former postdoc, Prof. Yugang Guo @YugangGUO2 @ZJU_China
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Credit to Vincent van Gogh as we were inspired by his famous painting 'The Starry Night' obviously 😀.
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We make it to the cover @NatureBiotech! the IL-10-CAR-T cells eradicate solid tumors! The IL-10-CD19-CAR-T cells have shown promising clinical results in several investigator initiated trials too. Stay tuned! #SOHC @myESMO @ASH_hematology.
nature.com
Nature Biotechnology - CAR T cells engineered to express IL-10 eradicate solid tumors and metastases.
The November issue is live On our cover, Zhao et al. show that expressing IL-10 in CAR T cells improves their mitochondrial function and therapeutic efficacy in multiple solid-tumor models
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Heading to PEGS Europe. will share our recent discovery of IL-10 CAR-T cells to treat blood and solid cancers!.
Attendee list preview for #PEGSEurope now available! More than 1500 attendees are expected in Barcelona for the "best #biologics technology meeting in Europe." Book by Friday and you can still save €400. #antibodies #proteinengineering #immunotherapy
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RT @JCubRuiz: Our new study published today @Nature uncovers that Transgelin 2 preserves T cell lipid metabolism and anti-tumor activity.….
nature.com
Nature - Together with the fatty-acid-binding protein FABP5, the cytoskeletal organizer TAGLN2 is an essential factor for fatty acid uptake, mitochondrial respiration and anticancer function...
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RT @MicheleCeriotti: Doing research in Surface and lnterface Science & Tribology, and want to join @Materials_EPFL @EPFL_en? Send your appl….
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RT @Materials_EPFL: Are you looking for a Faculty Position in Surface and lnterface Science & Tribology? The School of Engineering and The….
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A nice report by EPFL too! Thanks, Celia and Alain! “Unexpected immune response may hold key to long-term cancer remission”，
actu.epfl.ch
Results from a preclinical study in mice, led by EPFL, and a collaborative clinical study in patients show that the type 2 immune response – associated with parasitic infection and thought to play a...
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Exciting opportunity! Faculty Position of Metabolism at Tenure Track Assistant Professor level at EPFL. deadline is approaching. please spread the word.
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RT @ACIR_org: An Fc–IL-4 fusion protein reprogrammed cellular metabolism in terminally exhausted T cells in tumors, leading to enhanced cel….
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