IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastases https://t.co/yc2aepA0JS

Interested in working on the next generation of cancer immunotherapies? The Tang Lab at the Swiss Federal Institute of Technology in Lausanne is looking for a postdoctoral researcher with a strong background in immunology, metabolism, and mouse studies. See below for more info ⬇️

Thanks Pr. Richard Klemke for highlighting our work in Faculty Opinions. "Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity"- recommended in @FacultyOpinions

Thank ACIR for nice report for our work. https://t.co/dsMXpuUYUt

Our lab's new paper ( https://t.co/AGux9TqbJ2) on metabolic reprogramming of exhausted CD8+ T cells is now out at @natureimmunology, highlighted as a cover story! (1/7)

#cancer Tang and colleagues show that a half-life-extended IL-10–Fc fusion protein enhances proliferation and effector function of terminally exhausted T cells via metabolic reprogramming which can eradicate established solid tumors in mice. https://t.co/Ya9ccIJSOa