Stephan Grupp MD PhD
@GruppSteve
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#CARTCell expert, bone marrow transplanter, pediatric oncologist, husband to my vastly better half. All opinions my own, not an investor. RT not=endorsement🌊🌊
Philadelphia, PA
Joined December 2013
Call for abstracts at Tandem - not the abstract deadline is October 9!
Have you made a breakthrough in HCT, cellular or gene therapy? Showcase your work at #Tandem26 & discuss your findings with experts from around the globe. 🌍 Submit your abstract today! @CIBMTR 📅 Deadline: October 9, 2025 🔗 https://t.co/sBqBETNhXL
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Congratulations, Bruce, this is fantastic news and so well deserved!
I am deeply honored and humbled to have received the 2025 Merkin Prize in Biomedical Technology along with my long term mentor and colleague Carl June, and Isabelle Rivière, and Michel Sadelain. Innovation and translation of CAR T cell therapies first to clinical trials and
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🎻This was shown today at Cellicon Valley in the USA! It’s coming out tomorrow! “Ring That Bell”. Thank you all so much❤️ Thanks to all the scientists, doctors and nurses for all you.
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New #JITC article: CD22-targeted chimeric antigen receptor-modified T cells for children and adults with relapse of B-cell acute lymphoblastic leukemia after CD19-directed immunotherapy https://t.co/zh4ecsL6Pk
@MarcoRuella @gruppsteve @reginamyersmd @CarolineDiorio
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Congratulation to the 2025 class of Fellows of the @AACR Academy including @SU2C community members @NinaBhardwaj @IcahnMountSinai, @GruppSteve @PennCancer, Ari Melnick @WeillCornell, William Sellers @broadinstitute and Robert Vonderheide @PennCancer!!
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Just when you thought it couldn’t get any worse… It does. U Mich going beyond being forced into this to fully celebrating it.
Today the University of Michigan is ending implementation of DEI. We are eliminating programs, eliminating affiliated staff and ending the DEI 2.0 strategy. Late last year we ended the use of diversity statements in faculty hiring. This is now expanded university wide and
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In this @JCO_ASCO editorial, the author discusses two studies by CHOP's Dr. Ted Laetsch, emphasizing importance of precision medicine treatments that target specific genetic makeup of cancers, promising improved outcomes and reduced toxicity for patients: https://t.co/HJ1V8nmA3t.
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This is only the beginning of the consequences for the Senator’s vote to confirm RFKJr
This is a serious measles outbreak in Texas. The measles vaccine has been proven safe & effective since 1963.
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Why isn’t PA on the list of states suing to reverse this policy? @JoshShapiroPA @DePasqualePA @SenFettermanPA @upenn @CHOPCancerCntr @CHOP_Research
Brilliant strategy in this litigation over the Trump admin’s research gutting policy on paying NIH grants: Any relief the court orders only affects the 22 states that have sued, predominately blue states, putting the squeeze on GOP states to pressure the admin to rescind the
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This is 100% on brand for this lawless administration, dropping this bomb in the midst of everyone’s ongoing biomedical research without any warning or ability to prepare. Folks who were hoping for new gene therapies, new cancer therapies, new Alzheimers insights…not happening
Last year, $9B of the $35B that the National Institutes of Health (NIH) granted for research was used for administrative overhead, what is known as “indirect costs.” Today, NIH lowered the maximum indirect cost rate research institutions can charge the government to 15%, above
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Last year, $9B of the $35B that the National Institutes of Health (NIH) granted for research was used for administrative overhead, what is known as “indirect costs.” Today, NIH lowered the maximum indirect cost rate research institutions can charge the government to 15%, above
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Our Center recently celebrated its 600th patient treated with CAR T-cell immunotherapy, a groundbreaking “living drug” that utilizes the patient’s immune system to fight cancer. Pioneered at CHOP and @PennMedicine, CAR T has transformed cancer treatment worldwide.
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Many of you made Alex's birthday extra special this year by celebrating The 19th Annual Lemon Ball with us! To the more than 500 attendees and sponsors, we can't thank you enough for making this event so sweet. With your help, we raised more than $870,000! This is enough to fund
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Large long term CAR T safety data: -426 adults and 357 kids -tiny risk of 2nd cancers overall and lower in kids -lineage switch isn't a 2nd primary malignancy -many pts with long-term CAR persistence -many children in long term response/persistence category @CHOPCancerCntr
Long-term safety of lentiviral or gammaretroviral gene-modified T cell therapies - the @PennMedicine experience -38 gene engineered T cell therapy trials targeting HIV-1 or cancer -783 pts, >2,200 pt yrs of observation -Gammaretroviral or lentiviral vectors -Secondary
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Our Cell Therapy and Transplant group at @CHOPCancerCntr always looks forward to the annual @AlexsLemonade Lemon Ball. Always an amazing event, always so great to hear from the heroes and from Liz and Jay Scott. @CarolineDiorio @reginamyersmd
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We need to work together to get the therapies that people with #sicklecelldisease need! Today we meet at the @WhiteHouse to discuss #genetherapy so we can get #SCD transformed!! #WhiteHouseCGT
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Lots of key stakeholders in the room. Can we make access and the #cellandgene market work as well as the treatments do?
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Great discussions on cell and gene therapy access, especially the new curative cell therapies for #sicklecelldisease #Lyfgenia and #Casgevy from @bluebirdbio and @VertexPharma
#WhiteHouseCGT
CHOP's Dr. Stephan Grupp was invited to participate in the White House Cell and Gene Therapy Forum this week to discuss innovative approaches for advancing cell and gene therapy development, along with issues related to patient access and affordability. #WhiteHouseCGT
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