We make it to the cover @NatureBiotech! the IL-10-CAR-T cells eradicate solid tumors! https://t.co/hpFUqyuRGD The IL-10-CD19-CAR-T cells have shown promising clinical results in several investigator initiated trials too. Stay tuned! #SOHC @myESMO @ASH_hematology
The November issue is live https://t.co/Oh3jSUkWXw On our cover, Zhao et al. show that expressing IL-10 in CAR T cells improves their mitochondrial function and therapeutic efficacy in multiple solid-tumor models https://t.co/Sg45YuyQx3
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Credit to Vincent van Gogh as we were inspired by his famous painting 'The Starry Night' obviously 😀
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This cover art was based on real TEM images of mitochondria of exhausted CAR-T cells reinvigorated by IL-10. Kudos to Yiling Li, a PhD student of my former postdoc, Prof. Yugang Guo @YugangGUO2 @ZJU_China
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