Simran Kapoor
@SimranK64242265
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Hosts, Pathogens and Global Health PhD Student working on mast cells @ Gentek Lab University of Edinburgh 👩🏻🔬
Joined April 2022
Had a great time at the BSI SIGNET, really enjoyed all the fantastic talks and hearing about exciting immunology research🔬 And was honoured to receive a prize for my poster on #mastcells in the mammary gland! Special thanks to @lab_gentek @GentekRebecca #SIGNET2023
... and last but not least, a success for our own lab and #ProudPI moment with a poster prize for our PhD student @SimranK64242265 for her work on #mastcells in mammary glands👏🏻
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Had the fantastic opportunity to attend one of the best symposiums with fascinating talks in the field of neuroimmunology! Cutting edge science @WUSTL #ReThinkNeuroimmunology A brilliant scientific meeting! @jonykipnis @IdoAmitLab
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Really delighted to have our paper on PTPN22 in T cell exhaustion in cancer published in @jitcancer ! Thank you to the reviewers and editors for their insightful comments, and to all my co-authors who worked so hard to get it out
New #JITC article: Deletion of the protein tyrosine phosphatase PTPN22 for adoptive T cell therapy facilitates CTL effector function but promotes T cell exhaustion https://t.co/BCXs3SobSh
@alex_teagle @SimranK64242265 @BonesR620W @SalmondLeeds
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🆕 How do human hands and feet grow? A first-ever spatial limb cell atlas reveals genetic and cellular processes behind human limb development This will help us find new ways to diagnose and treat limb syndromes 🔬 https://t.co/rzmSlT5xS6
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New #JITC article: Deletion of the protein tyrosine phosphatase PTPN22 for adoptive T cell therapy facilitates CTL effector function but promotes T cell exhaustion https://t.co/BCXs3SobSh
@alex_teagle @SimranK64242265 @BonesR620W @SalmondLeeds
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The PostDoc dream team! @lab_gentek Often found pipetting and occasionally in the pub discussing groundbreaking ideas (2/3 of these activities being sponsored by the PI @GentekRebecca). Great colleagues&friends🏆 #LovePostdocs #PostdocAppreciationWeek
@EdinUni_IRR @BQPDS
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Excited to announce that the 1st patient has been dosed with our first-in-class monoclonal antibody, in a Phase 1b #clinicalstudy in #cancer patients. We are very grateful to the participants volunteering to enrol in the ‘ATTAINMENT’ study. Full story: https://t.co/BQ7jtdg9Mc
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In @ScienceMagazine this week, Ziegler, Engelhardt & al (@TU_Muenchen, @dzhk_germany) report that #sleep disruption in #HeartDisease is driven #macrophage-mediated loss of #neurons projecting from #SuperiorCervicalGanglia into #PinealGland! https://t.co/5moq1ZxUlE
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Combining whole-tissue imaging & single-cell RNA sequencing datasets, Tauber, Basso, Martin et al @InfinityTLS present a pan-organ analysis of mast cells (MCs) in mice & humans at steady state, revealing an unexpected heterogeneity of MC populations https://t.co/tE4TEoVmps
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And there's more to #mastcells! Two studies identifying their key role in mediating food avoidance. Congratulations to @Plum_immunology and @florsheim_eb and the Rodewald and Medzhitov labs on landmarking studies and creative technological approaches👏🏻
The immunology that underlies picky eating https://t.co/R32clsLsoZ Fascinating studies led by @florsheim_eb & @Plum_immunology uncover the #neuroimmune pathway linking #allergic response with food avoidance. #MastCells play a crucial role, bridging immunology & behavior!
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Opinion special issue: Systems immunology II 'Conditioning of the immune system by the microbiome' from Daniel Graham & Ramnik Xavier @broadinstitute @Harvard
https://t.co/jiFYfwWRgS
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In the latest issue! A sound mind in a sound body: Stress-induced glucocorticoids exacerbate gut inflammation
cell.com
The notion that psychological stress can deteriorate our health is widely accepted. However, the mechanisms at play are poorly understood. In this issue of Cell, Schneider et al. identify the impact...
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People with inflammatory bowel disease may notice flare-ups during stressful times. Researchers have now found the mechanism behind that
newscientist.com
A pathway between the brain and the immune system discovered in mice could explain why prolonged stress can exacerbate inflammatory bowel disease
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Medannex's Fiona Dempsey looks forward to this lively panel at #BioIntegrates next week. With high specificity & low tox, monoclonal #antibodies continue to offer huge therapeutic benefits & lead all #biopharmaceuticals in approvals/sales. The future looks bright! @LSIntegrates
Join the discussion on therapeutic antibody design & engineering @ #BioIntegrates, with Alan Boyd @boydconsultants, Marc Wilkinson @J_A_Kemp, Jolyon Martin @PetMedix, Adrian Kinkaid @FsnAntibodies, Fiona Dempsey @MedannexLtd & Carolyn Flanigan @AbsAntibody
https://t.co/sjSdIc4ogB
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Thanks to @ourdynamicearth for hosting @EdinburghUni and @NHS_Lothian for Our Planet, Our Health and Our Future -privilege to present with the @born_scotland team and to open conversations on what collective action for health means with @alillyf @goldenshauna123 @GroundswellCon
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Our very own @YoCorripioMiyar telling a rapt audience about T-helper immune phenotypes and parasite infection in @SoaySheep at #BSP2023
@MoredunComms
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🚨 Read all about #mastcell ontogeny & when and why we think it matters - our new review at #ImmunologicalReviews 🚨 https://t.co/XZzpcKDNoz Written with PhD students @shinli96 @SimranK64242265, postdoc @CarvalhoCyril @EdinUni_MeetCIR @MRC_CRH and @BajenoffL @CIML_Immunology
onlinelibrary.wiley.com
Mast cells (MCs) are evolutionarily ancient innate immune cells with important roles in protective immunity against bacteria, parasites, and venomous animals. They can be found in most organs of the...
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