Seth Thomas Scanlon
@ImmunoEditor
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Editor, Science Immunology 🇺🇸 + 🇳🇱 & based in 🇪🇺 Bluesky: https://t.co/MXWrwj8Sak
The Netherlands
Joined October 2017
I have decided to give #Bluesky a try! So, for the time being, I will upload parallel posts both here and there! Follow me at https://t.co/3SIjow1HYI!
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This is a public service announcement: late-breaking abstract submissions for #IUIS2025 will close tomorrow (May 6)! You can submit your abstracts here: https://t.co/aYW2qm6iVT I hope to see many of you this August in beautiful Vienna!!! #Immunology #CallForAbstracts #IUIS
iuis2025.org
ABSTRACTS ALL ABOUT SUBMISSION LATE ABSTRACT SUBMISSION IS NOW CLOSED THANK YOU FOR YOUR CONTRIBUTIONS! guidelines LATE ABSTRACT SUBMISSION GUIDELINES Important Dates 20 November 2024 – Abstract...
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This is a public service announcement!
Great abstracts submitted to #PeritonealSummit resulting in an awesome final program: https://t.co/P4dMtIGlqg. Registration open until December 15th. Only few spots left! @Kubes_Lab @erinadelle17 @ImmunoEditor @LucyHJackson @CecileBenezech @ProfJudiAllen
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The December issue of #Science #Immunology is out now! This week: #MAITcell plasticity in #antibacterial immunity; how #inflammatory status of #lung before #COVID19 infection impacts #viral control; & #helminths utilize glutamate dehydrogenase to prevent #AAMs & #TH2 activation!
Science #Immunology's December issue is out! This month's cover spotlights how worm-like #parasites called #helminths suppress immune responses and facilitate chronic infections in mice. Read this research and more: https://t.co/jpbopqCZho
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I am so looking forward to attending #Peritoneal Summit 15–17 JAN 2025 in beautiful Pontresina, coörganized by @JoelZindel & @IngeKHermann! It should be a great meeting on burgeoning field of body cavity immunity! Come join us! Abstract deadline 30 NOV! https://t.co/Uy5AL3VKgd
peritoneal-summit.com
Join the Peritoneal Summit Meeting in Spiez, Switzerland for cutting-edge biomedical research, networking with experts, and exploring innovative treatments. Register now!
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This week in @SciImmunology, @jacki_hf, Carl Walkley & colleagues used a genome-wide #CRISPRscreen to determine that a GGNBP2– CNOT10/11 complex is required for the accumulation of unedited #immunogenic self-#dsRNA & its sensing by #MDA5! https://t.co/E2wr5SFUde
science.org
GGNBP2, CNOT10, and CNOT11 are required for innate immune response after the loss of ADAR1-mediated editing of self dsRNA.
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Now in @sciimmunology, Ransmayr, @KaanBoztug, & al describe patients w #IEI caused by #biallelic #LOF mutations in #LTB. LTβR signaling shapes #human #SLO microarchitecture & immune function in ways unanticipated by earlier 🐭studies! https://t.co/UAviqAm2vt
science.org
Loss-of-function mutations in LTBR result in a stromal defect, leading to dysfunctional secondary lymphoid organs and combined immunodeficiency in humans.
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In @SciImmunology last week, Zhang&al reported stability & expression of #ImmuneCheckpoint molecule #TIM3 regulated by palmitoyltransferase DHHC9. Peptidic inhibitor of DHHC9 accelerates TIM-3 degradation & enhances #CARTCell & #NKCell #antitumor immunity! https://t.co/dNsBRioTGl
science.org
Targeting TIM-3 palmitoylation mediated by DHHC9 enhances CAR-T cell– and NK cell–based tumor immunotherapy by suppressing immune exhaustion.
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This week in @SciImmunology: @DemariaO, @EricVivier1, & al. use tetraspecific #NKCell engager (comprising an α-#NKp46 Ab fragment + #IgG1 #Fc fragment + #IL2 variant + α-#CD20 Ab) to target #BCell-specific #NonHodgkin #lymphoma in mouse & NHP models! https://t.co/YQwhChfYF6
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This week in @SciImmunology: some fantastic work from @VirusesImmunity & collegues! Be sure to check out her really helpful tweetorial below!
Happy to share our latest work by @YYexin et al. on antibody-mediated control of endogenous retroviruses in mice. In the process, we found “natural antibodies” with broad reactivity against enveloped viruses. Here is how “panviral” antibodies work 🧵(1/) https://t.co/kU8NBK5KF9
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This week in @ScienceMagazine: @jerika_barron, @Molofsky_lab, @AnnaMolofskyLab, & colleagues report that #ILC2 promote #postnatal #synapse formation in the #brains of #mice. An absence of ILC2 leads to impaired #social #behavior in adult mice! https://t.co/3tpL17b0IC
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Our cover story this month features some absolutely exquisite work from @brunaraujodavid, @Kubes_Lab, and colleagues! We are so excited to share it!
I’m delighted to share my postdoc work is now out in @SciImmunology! We investigated the role of liver-resident macrophages, #Kupffercell, in newborn bacterial infections and their link to #sepsis and #meningitis, unveiling a surprising phenomenon. https://t.co/8RBMauoEIJ
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The November issue of @SciImmunology is out now! This week: new insights into #DC #CrossPresentation; a #Focus on #monocyte heterogeneity; & #intravital #microscopy shows how #KupfferCells seed #liver #sinusoids in #EarlyLife! Additional content each week! Check it out!!!
Science #Immunology's November issue is out! This month's cover highlights new research that suggests that delayed relocation of liver macrophages, or #KupfferCells, into blood vessels underlies newborns' susceptibility to bloodstream infections. https://t.co/JJCWSt6Efe
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Last week's @CytokineSociety #cytokines2024 meeting in Seoul was amazing! To celebrate, @SciImmunology has just released a free sample collection of papers highlighting the immunology of #cytokines! Articles are free online to read for the next 6 weeks! https://t.co/Utc6X4KQbF
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The latest issue of @SciImmunology is out now! New content every week! Check it out!
Science #Immunology's October issue is out! This month's cover highlights how #NFkB signaling helps recruit the noncoding RNA Xist to maintain #XChromosomeInactivation in activated T cells. Read this research and more: https://t.co/sfmAjsRlhs
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What a fantastic @ImmunOctober conference! Thank you, Dietmar, Ben, & Anna for organizing such a masterful meeting! We are already looking forward to Memphis 2026!
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@ImmunOctober @SciImmunology Photo credit: "München, Löwenbräu-Festhalle, Oktoberfest 2012" (Bayreuth2009 / Wikimedia / CC BY 3.0)
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To celebrate the @ImmunOctober meeting this week in #Munich, @SciImmunology has released a sample collection of papers in the fields of #TCell #differentiation & T cell #immunotherapy! Articles are free online to read until the end of Oct 2024! https://t.co/3vLsxmHjWT
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The September issue of @SciImmunology is live! This week: #human #MAITCell heterogeneity across tissues; dev origin of #monocytes & #epidermal niche signaling imprint #LangerhansCell identity; & #IgE-producing #PlasmaCells have a unique phenotype! New content added each week!
Science #Immunology's September issue is out! This month's cover spotlights the unique properties of plasma cells that produce allergy-driving immunoglobulin E (#IgE). Other work looks at #Langerhans cell development, human #MAIT cells, and more. https://t.co/T8NygCrNkP
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In @SciImmunology this week, @emma_houlder, Koen Stam, Maria Yazdanbakhsh, Meta Roestenberg, & al. at @LUMCPara track how immune responses evolve over time in #schistosomiasis using controlled #Schistosoma mansoni infections of human volunteers! https://t.co/dAKfYL9G5z
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