Today out in @biorxivpreprint we present SCOPE. An optics-free, self-registering array of DNA encoded beads for spatial genomics. This was work led by the intrepid duo of Hanna Liao and Sanjay Kottapalli, with @JShendure's lab.

Are you an experimental biologist interested in working at the frontier of AI x Bio? Then come work with the life sciences team at Anthropic! Experienced wet lab wizards are welcome to apply. https://t.co/2m9YEjfwqp

There's a new DARPA program on "Generative Optogenetics." The goal is to write DNA or RNA directly in cells using flashes of light, rather than building it in tubes, transforming/growing cells, and so on. If it works, it could speed up molecular biology experiments. Cloning

NSF is launching one of the most ambitious experiments in federal science funding in 75 years. The program is called Tech Labs, and the goal is to invest ~$1 billion to seed new institutions of science and technology for the 21st century. Instead of funding projects, the NSF

We sought to make proteins both potent and FAST. We used #proteindesign to design precise control over protein interaction lifetimes, enabling us to construct rapid-response circuits, biosensors, and switchable cytokines. Now published @Nature! Links to paper and tutorial below.

I’m hiring a PhD student! Come work on #CRISPR + Cancer + T cells 🧬 and help push the boundaries of next-gen immunotherapy. Join us in Copenhagen 🇩🇰 at @DTU_HealthTech !!! Deadline: 30 Sept 2025 https://t.co/XnQ2IuaNPR

Introducing the 1,000 Flower Collection 🧬🌹 I’m creating 1,000 genetically designed flowers each crafted with new colors, patterns, and shapes. Here’s how I’m making it happen…  and how you can join me on this journey 🧵(1/7)

A flower designer in the UK ( @NickDesnoyer ) is using breeding, genetic engineering, and even pathogenic infections to create 1,000 original flowers. His name is Nick Desnoyer, and he does this work in his spare time, after his labmates have left for the day. He does not make

Excited to share our work with @julie_trolle and @JefBoeke We developed a 'shotgun' method to screen millions of synthetic metabolic pathways to enable mammalian cells to grow without two essential nutrients for the first time in >500 million years! https://t.co/260aCqjme8

A team of researchers reached into the genome of a seven-month-old baby with a base editing therapy targeted specifically to repair his unique mutation. Now nine months old, baby KJ, as he is known, appears healthy https://t.co/p5rsKuo1qW https://t.co/OwSYoZT2Si

Please RT🔁 I will be hosting this Synthetic Biology Workshop at @WPI_PRIMe in Osaka on July 15. Great lineup of speakers: @_mattrich, @Lab_Nagai, @CarldeBoerPhD, @nikashakiba, @kenjikamimoto68, @tToshimichiY. The event will be followed by a networking session🥸

Procrastinators unite! 4 hours left for Flux applications!

Hiring alert! @SRsrivatsan @fredhutch and I @HHMIJanelia are looking for a joint postdoc to combine single-cell omics and ex utero embryogenesis. Please retweet! If you are interested, DM us or send an email to sanjay@fredhutch.org ; alejandroac@janelia.hhmi.org

New preprint! We carried out the largest complementation and inhibition study for diverse homologs in a single protein family (DHFR) to date. Highlights thread follows... 1/n 🧵

Our annual DSA scientific retreat is just around the corner! We will be celebrating our 2024 DSA winners: @zz_zhaozhang, @WangLabUIUC, @SRsrivatsan, and @crcadwell. If you would like to become a DSA awardee, the application portal is now open! https://t.co/BKNHWu5HvB

Since we announced the FutureHouse AI for Science Fellowship, we've had a bunch more amazing professors sign on as potential co-advisors: Sergey Ovchinnikov (MIT) Ellen Zhong (Princeton University) Patrick Hsu (UC Berkeley/Arc Institute) Pratyush Tiwary (University of Maryland)

We need more programs like this one (@FutureHouseSF) to bring new ideas into the biological sciences. As mentioned in the fellowship link, our lab is excited to co-advise fellows who want to solve the world’s biggest problems with cutting edge tools. DM me if you want to talk

Grateful for the support of the Sontag Foundation, we’re excited to do this important work!

E11 Bio is excited to share a major step towards brain mapping at 100x lower cost, making whole-brain connectomics at human & mouse scale feasible (🧠→🔬→💻). Critical for curing brain disorders, building human-like AI systems, and even simulating human brains. 1/N 🧵

New work by Mia Yang's lab reports evidence of prevalent aneuploidies in human trophoblast stem cells and suggests that chromosomal instability may be a normal feature of placental development.

I am ***absurdly*** excited to announce the launch of a new funding opportunity through Experiment dot com!!! You have one month to pitch something wonderful in the realm of plant biology/biotech research and education. $10,000 max grant. PLEASE RT!!! 1/3 https://t.co/Jlae6SIQcg