Richard Voit
@RichardVoit
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Pediatric hematology/oncology | Stem cell biology | AML | Gene therapy | CRISPR
UT Southwestern
Joined December 2021
Gene therapy is transforming how we treat genetic disorders, but what if mutations in more than 30 genes can cause similar symptoms? Now published in @CellStemCell ( https://t.co/Ub72yvUo0c), we report the development of a universal gene therapy for Diamond Blackfan anemia. 1/n
cell.com
Gene therapy for Diamond-Blackfan anemia is constrained by dozens of causative mutations. Voit and colleagues develop a universal gene therapy through erythroid-lineage-restricted expression of GATA1...
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Congratulations @Mendell_lab. What an interesting mechanism!
Colliding ribosomes are potent signals of cellular stress. But do cells use ‘programmed’ ribosome collisions to regulate gene expression? I’m excited to present a new story led by Frederick Rehfeld revealing that the answer is YES! Read on to find out how.
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Congrats! 👏👏👏 Two CRI scientists named 2025 Pew-Stewart & Pew Scholars — @JaviGBermudez & @HijaiShin — to advance cancer, biomedical research. Read more about their #relentlessdiscovery ⬇️ https://t.co/MAFSU4zUqs
@pewtrusts
cri.utsw.edu
Javier Garcia-Bermudez, Ph.D., Hijai Regina Shin, Ph.D., selected to advance cancer, biomedical research DALLAS – Aug. 12, 2025 – Two Children’s Medical Center Research Institute at UT Southwestern...
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Looking forward to the #NFRF2025 @UTSWScience in October. https://t.co/mTjnLXxZzM. If you are an undifferentiated trainee @UTSWMedCenter, come check out highlights from new labs on campus.
utsouthwestern.edu
2025 New Faculty Research Forum
Committed to advancing treatments for children with blood disorders, @RichardVoit is exploring the complexities of hematopoietic stem cells to enhance targeted leukemia therapies. Discover more: https://t.co/w3e9TvHjaK
#NFRF2025 #NFRF
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Inspiring piece in @NatureCancer, "An unexpected career in cancer metabolism," highlights Dr. Ralph DeBerardinis & the pivotal moments that prompted him to pursue a career in cancer metabolism. @CRI_UTSW @HHMINEWS
nature.com
Nature Cancer - Ralph DeBerardinis obtained an MD and PhD from the University of Pennsylvania, then trained in Pediatrics and Medical Genetics at Children’s Hospital of Philadelphia. He moved...
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Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia - by @ShellainaGordon @florian_perner, @Armstrong_dfci, @MAF_Dawson @TheDawsonLab et al. https://t.co/hdfSLRw7SU
@PeterMacRes @DanaFarber
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KAT6A and KAT7 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98-Rearranged Acute Myeloid Leukemia @NMichmerhuizen, Emily Heikamp, @Armstrong_dfci, @CMullighan and colleagues https://t.co/orc4w45Iw8
@StJudeResearch @DanaFarber
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Be part of the Wagenblast Lab! We are hiring a Lab Manager for leukemia & blood stem cell research at @IcahnMountSinai in NYC, starting July 2025. See ad to apply!
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Congratulations @michaelpoeschla and @bloodgenes. Incredible work!
Delighted to have our work on Polygenic Modifiers of #TelomereBiologyDisorders, led by @michaelpoeschla, along with @SashaGusevPosts, @mitchiela, @SharonSavageMD, @hemanth_tummala, and others, published as an advanced online paper in @jclinicalinvest today:
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Excited to share with all our latest work on the use of single cell tools in following IDH mutant AML patients during their treatment! Out today @CellStemCell !! An amazing collaboration with @AkEisfeld & @PapaemmanuilLab & @landau_lab !!! Driven by the impressive @MariaSirenko
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Kids like KK motivate everything we do in the lab @utswcancer @CRI_UTSW @UTSW_PedsHemOnc. We are now hiring so if you are looking for the next step in your scientific journey or want to learn more about what we do, please reach out.
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We at https://t.co/h1JtA2Hva3 are grateful to @TexasCCF for supporting our work. Thank you also to @dallascowboys @dak, @Jalen8Tolbert, @tonyromo, @TroyAikman for using their platform to raise awareness and funds for pediatric cancer research.
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Congratulations Elvin and team. This is a really elegant way to probe an important clinical question underlying aggressive AMLs.
Thrilled to share the first pre-print from our lab! We tackled a big question: Why are some pediatric leukemias extremely aggressive? We explored the developmental origins of fusion-driven acute myeloid leukemia (AML). Let's dive in! #AML #NUP98 n/13
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Delighted to have our Perturb-multiome paper, led by @jmartinrufino and #AlexisCaulier from our lab, published today in @ScienceMagazine. Please check out this powerful approach to decipher gene regulatory networks enriched for genetic variation:
science.org
Most phenotype-associated genetic variants map to noncoding regulatory regions of the human genome, but their mechanisms remain elusive in most cases. We developed a highly efficient strategy,...
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Congratulations to @DanaFarber’s Lara Wahlster, MD, PhD, and Nina Weichert-Leahey, MD, for receiving the American Society for Clinical Investigation Emerging-Generation Awards. Read about Dr. Wahlster at https://t.co/NNeN0AHxXu and Dr. Weichert-Leahey at https://t.co/44tEObGr0E.
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Incredibly proud of @tGaoTeng from our lab, who is a recipient of the @HHMINEWS-@DamonRunyon fellowship!!! Congratulations, Teng!! https://t.co/eTTpbro6wl
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I am so excited to be selected as one of the recipients of the Michelson Prize from the Michelson Medical Research Foundation and the @ImmunomePro! This award enables our lab's research at the intersection of systems immunology, virology, and large-scale genomics research.
Congratulations to Dr. Caleb Lareau, 2024 #MichelsonPrizes recipient! His work will study the blood virome and answer the critical question: how do humans have vastly different responses to the same infection?
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Congratulations @LWahlster of @DanaFarber who has been named a 2025 Damon Runyon-St. Jude Pediatric Cancer Research Fellow. Read more: https://t.co/vGkfzU5Cgb
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What a fun time presenting our work on gene therapy for Diamond Blackfan anemia at the Tandem BMT meeting today! They even took pity on me as a hematologist and named me an honorary transplanter for the week.
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Gene editing without ex vivo culture evades genotoxicity in human hematopoietic stem cells
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