RT @jrbperry: 1 week left to apply to join our statistical genetics team at the @IMS_MRL. Junior or senior scientist opportunities availabl….

RT @charles_breeze: My first career podcast interview! Couldn't be happier! 🎉🎉🎉🎉 Thank you @EverythingEpi @TruDiagnostic ! I would like to….

Online in @AJHGNews is our renal cell carcinoma (#RCC) transcriptome- and proteome-wide association study lead by @Diptavo that identifies potential molecular targets for downstream functional investigation.@NCIEpiTraining.

Our investigation in UK Biobank identifies social, behavioral and clinical risk factors associated with clonal hematopoiesis and details differences in effect based on type of CH (e.g., CHIP, autosomal mCAs, mLOY and mLOX).

RT @AJHGNews: 🚨 Online now!.📰Transcriptome- and proteome-wide association studies identify genes associated with renal cell carcinoma.🧑‍🤝‍🧑….

Our TWAS analyses in four normal and tumor #kidney transcriptomes and 48 GTEx tissues identified several important genes with relevance to #renal cell carcinoma overall and its subtypes. @Diptavo @NCIChanock.

RT @Aoxing2: Thanks, @SafiaDanovi, for a lovely "Research Highlight" in Nature Genetics about our "understanding X chromosome loss"!! 🧬🧬🧬….

Genomic investigation of Chernobyl #thyroid cancer cases finds cervical lymph node #metastases are more frequent in fusion versus mutation drivers, although the proportion varies by driver gene. No effect is found for radiation exposure. @NCIEpiTraining.

@Nature A full text version can be found here:.

@Nature . @pnatarajanmd @dalygene @AlexBickMDPhD @s_mccarroll @ChikashiTerao @andganna @jrbperry and many others!.

@Nature As well as many terrific collaborators including @Aoxing2 @freeseek82 @ZhaoDylan @MattiPirinen @zekavatm @aikat33 @ZhiyuHas0Memory @DrFlashHeart @DerekWBrown_1 @BRGorman @joe_jgd29 @WeiyinZ @ndfreedman @bloodgenes @APalotie @HannaMOllila @ttukiainen @NCIChanock @m_reedik. .

@Nature This was a tremendous effort spanning 8 international biobanks and several institutions including @theNCI @NCIEpiTraining @Cambridge_Uni @broadinstitute @FIMM_UH @FinnGen_FI @ESTbiobank @uk_biobank.

Online today in @Nature! We characterize age-related mosaic loss of the X chromosome (#mLOX) in 800K women, examine associations with disease risk, and identify germline variation associated with susceptibility as well as the retained X chromosome.

RT @theNCI: The #DNA a woman is born with may influence how her cells respond to chromosomal abnormalities acquired with aging, according t….

RT @freeseek82: How do you process genotype data from almost a million women across eight biobanks each with different security restriction….

RT @Aoxing2: New out in Nature!! .With age, women can lose one X chromosome in their leukocytes. What’s the cause/consequence? .How does it….

RT @AlexBickMDPhD: 12% of women across 8 biobanks exhibited detectable mosaic Loss of X chromosome in >2% of blood cells. Delighted to be….

Online today in @NatureGenet is a multi-ancestry #GWAS of renal cell carcinoma #RCC that identifies 50 novel loci, subtype specific loci for clear cell and papillary subtypes, and an African ancestry-specific association at VHL. @NCIEpiTraining #NCI_ITEB.

ArCH is a terrific new pipeline from the Bolton group for variant calling, filtering and annotation that improves the sensitivity and positive predictive value of #clonal #hematopoiesis variant detection at low allele frequencies.

RT @charles_breeze: 🚀 Exciting update! 🧬 FORGEdb + LDlink now cover billions of new regulatory variant annotations. .