“The KIDS25 BioHackathon demonstrates how we’re building the St. Jude data science workforce for the future. These aren’t just 72 hours of coding; they’re an investment in the people who will drive the mission forward for years to come,” said @renato_umeton, VP of Data Science.

This year, 160 participants worked on 21 projects as many groups embraced using artificial intelligence (AI) to tackle their challenges. The best overall project was awarded to the team who developed a multi-modal agentic AI system for prioritizing the effects of cancer variants.

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St. Jude recently hosted the KIDS25 BioHackathon, an event connecting students and professionals in bioinformatics, imaging, data science, artificial intelligence and software engineering to develop solutions addressing real-world research challenges.

This discovery clarifies how disruptions in stress granule regulation can contribute to conditions such as multisystem proteinopathy, amyotrophic lateral sclerosis and frontotemporal dementia, highlighting potential therapeutic targets.

New findings reveal that the ASPL protein plays distinct roles in both the assembly and disassembly of stress granules—mechanisms linked to neurodegenerative diseases.

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Now a PhD student at @stjudegraduate, Bondrowski studies CAR T cell therapies for childhood tumors. “Every day I walk through the halls of St. Jude, and I see children and families holding onto the possibility of better outcomes. That hope is what drives me.”

Jordan Bondrowski’s journey to cancer research started at age 11, when she chose to donate a reward for returning a home run baseball to breast cancer research. Years later, losing her aunt to metastatic melanoma motivated her to pursue biomedical science. https://t.co/Es43c8dfee

Hayley Arceneaux went from St. Jude patient to physician assistant to astronaut and now her Inspiration4 spacesuit is here at St. Jude for all to enjoy. 🚀 The suit that soared 366 miles above Earth and helped raise $250M for childhood cancer research is even cooler in person.

St. Jude is advancing therapies such as immunotherapy and precision medicine while expanding global access to care through collaborations with WHO, UNICEF and others.

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"To be named among the top children’s cancer hospitals every year since the rankings began is a reflection of our people—their brilliance, their heart and their unwavering commitment to our mission,” said James R. Downing, MD, president and CEO.

St. Jude Children’s Research Hospital has been ranked among the top 10 pediatric cancer hospitals by U.S. News & World Report for the 18th year in a row. Read more: https://t.co/adVuJhs2Tu

Alongside wellness programs, growth opportunities and more, our new childcare center sets us apart in our support of our staff’s well-being. “The center was near full subscription not long after opening,” said Maria Megdal, EVP and chief administrative officer.

Proud to be ranked No. 2 on the @Forbes list of Best Employers for Healthcare Professionals! At St. Jude, we invest in our team so they can focus on our lifesaving mission. https://t.co/hohX3kptxV

The application deadline for the 2026 CCSS Ann C. Mertens Career Development Award has been extended through Monday, November 3. This is a great opportunity for early-career investigators interested in childhood cancer survivorship research. Learn more:

“These methods are now being used by other labs to study important processes in the brain in ways that haven’t been done before,” said @lindsayschwarz, PhD. As technology continues to evolve, St. Jude researchers are lighting the way to new knowledge.

Innovations include self-healing fluorophores for more precise imaging, an intersectional genetic platform to label rare neuronal populations and the first visualization of cytonemes in mammalian tissue. All discoveries are driven by advances in fluorescence and microscopy.

St. Jude researchers are advancing science by harnessing light-based technologies to explore the molecular and cellular mechanisms underlying health and disease. https://t.co/kiqjIG4n3W

The work continues. Register to join us at our October stakeholder engagement webinar to keep building hope and better outcomes for kids everywhere: https://t.co/gV64iegVpE #GlobalHealth #UNGA

This event showed the power of collaboration, sharing best practices, fostering new partnerships & driving action for sickle cell disease and childhood cancer. The convening power of St. Jude brings leaders together to build lasting, resilient health systems for all children.

At #UNGA80, St. Jude & Uzbekistan co-hosted a landmark side event, united by Bente Mikkelsen’s leadership, 8 first ladies, @WHO DG @DrTedros & ministers of health worldwide. Together, we’re advancing global health for children facing catastrophic diseases.