We’re very excited to share the first preprint from my lab along with @h4rrymcnamara, @BillZJia, @AdamEzraCohen, and Alex Schier. We describe a set of methods for exerting spatial control over Nodal signaling in zebrafish development. https://t.co/4Opufofwop

Our lab at @YaleMed seeks #postdocs with in vivo expertise to pioneer research at the intersection of tissue remodeling & aging. Work with us to uncover immunological & vascular drivers of ovarian aging, applying single-cell, spatial omics, and ML!

Our paper is now out in final form at Nature Genetics! For those who missed the preprint, we used large-scale Perturb-seq targeting transcription factors to push primary fibroblasts into diverse transcriptional states, including those observed in cell atlas studies.

Also: check out the awesome accompanying paper from @GetYourChorion that uses our tools to pick apart how Nodal signaling dynamics inform morphogenesis! https://t.co/9TYUaYdcGG

We're very excited to have the final version of our paper up in @Dev_journal. We describe a new system for spatial control of Nodal signaling in live embryos. Thanks to Development for a helpful and constructive review process! Please reach out if you'd like to try our tools!

I wrote a 'Behind the Paper' blog post for @the_Node narrating the origin story of our recent @NatureCellBio paper on recording signals during gastruloid symmetry breaking. have a read if you're curious! https://t.co/t8VrD8W1VF

Read below for the latest from Emily Ho in my lab on in vivo receptor tyrosine kinase biosensors. This has been a *dream* project, seeing endogenous RTK activity in live embryos for the first time. Surprise: they don't always match those of downstream signaling pathways!

My team at Deepmind (protein design) is hiring an experimentalist with enzyme expertise. Please RT and/or apply! I'm happy to answer any questions as well.

Get in on the ground floor! Working with @h4rrymcnamara was a highlight of my scientific career. He is brilliant, creative, and a joy to work with. His lab is going to do awesome things. Definitely seek him out if you're looking to get into developmental biology for PhD/postdoc.

Our paper “Dynamics of morphogen source formation in a growing tissue” with first authors R. Ho and K. Kishi is published in @PLOSCompBiol 🎉 We show that the floor plate of the vertebrate neural tube forms in two phases: rapid specification followed by growth. 🧵1/7

What if you could find out the history of signaling activity in each cell with a single round of imaging? Wouldn't that be incredible? Well, we thought so too. And that's what we set out to achieve with INSCRIBE in our new preprint. Let’s dive in! 🚀🔬 https://t.co/J634soGHwz

Working on this paper with @h4rrymcnamara was just an absolute pleasure, one of the highlights of PI life so far. Even better: he'll be starting his own laboratory in just a few months at Yale - so stay tuned for more exciting work from the McNamara group!

Check out our latest preprint on FGF/ERK signaling in 2D gastruloids: https://t.co/ZTPmLHZfyZ

Thank you @BWFUND for supporting our work decoding stem cell self-organization! Thrilled to join this community of investigators at the interface of the biological and physical sciences. This award will provide a huge lift to my next phase (more news on that soon! 😺)

So excited to announce our new method for multiplexed RNA imaging in bacterial cells: bacterial-MERFISH! A huge congratulations to the team of @AriSarfatis, Yuanyou Wang, and Nana Twumasi-Ankrah! Check out the following thread or our bioRxiv ( https://t.co/qESwAKeWpO) 1/12

Our latest: a new optogenetic system for precise spatiotemporal control of gene expression We use it to dissect the dynamics of Shh gradient formation & patterning A thread 🧵 https://t.co/Ki4COIjVcl

It's new-preprint-from-the-lab day! (In my opinion the most fun + authentic day to celebrate a new publication.) Check it out: "Large-scale control over collective cell migration using light-controlled epidermal growth factor receptors" https://t.co/PSpibn428y

Join us for the 2024 Optogenetics Technologies conference in Boston! Outstanding lineup including: @AdamEzraCohen, @KhammashLab, @MoeglichLab @toettch @ProfJohnARogers @DunlopLab @coledeforest , Haifeng Ye + many more. 🗓️Sept. 10-12 Abstracts due 6/7! https://t.co/qqAWqLh9kF

1/ Our work on unified principles for Topographic Deep Artificial Neural Networks is finally out in Neuron! 7 years in the making.

I am incredibly excited and honored to be running for the Secretary position for the Society of Developmental Biology! If you are a member, I would appreciate your support and your vote. I'd love the opportunity to serve our community in this way. Thanks!! Plz RT!

Congratulations to you and @elecamagu ! Wonderful story.