I wrote a review (with @_JosephWatson @sid_thesci_kid ) on protein design using structure prediction models--i.e. hallucination, inpainting, diffusion. This approach to protein design started as a convenience but has turned out to be surprisingly powerful.

RT @davidrliu: In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, stud….

RT @ginaelnesr: Protein function often depends on protein dynamics. To design proteins that function like natural ones, how do we predict t….

RT @alexechu_: Our team has a Student Researcher position available for this year! probably in something related to protein modeling & desi….

RT @_JosephWatson: I’m excited to share our significantly-updated preprint on de novo antibody design, where we now demonstrate the structu….

RT @DaveJuergens: Anna and Sam figured out subtle geometric details of serine hydrolase active sites, and then figured out how make new pro….

Deep mutational scanning of Rubisco, from @NoamPrywes @SavageCatsOnly (I really liked the note in the "Behind the paper" section):

RT @BingxuL: We are all born with a genetic lottery. Millions of T cell receptors are what we have with a hope to defend all cancer and vir….

RT @chrisfrank662: After showing that AF2 can be used to design very large proteins by performing #RSO, I am happy to share another fun pro….

RT @SurgeBiswas: Incredibly excited to share new results from Nabla Bio where we show we can design antibodies de novo for use in therapeut….

RT @adam_broerman: Excited to announce our new #proteindesign strategy for allosterically controlling the kinetics of protein-protein inter….

My team at Deepmind (protein design) is hiring an experimentalist with enzyme expertise. Please RT and/or apply! I'm happy to answer any questions as well.

RT @pushmeet: The #AlphaFold 3 model code and weights are now available for academic use. We @GoogleDeepMind are excited to see how the res….

RT @UWproteindesign: 🔴 LIVE in 25 minutes: Computational Protein Design Then & Now (1988-2024). A free one-hour webinar featuring:.David Ba….

RT @generate_biomed: In a new article for @Nature, journalist @Sara_Reardon explores “Five structural-biology questions that still challen….

RT @NoamPrywes: Congrats to the team for this incredibly bizarre and perplexing result. Leaving out a chaperone causes hornwort rubisco to….

RT @liambai21: Remember Golden Gate Claude? . @etowah0 and I have been working on applying the same mechanistic interpretability techniques….

RT @chrisfrank662: Finally, out in @ScienceMagazine today, our work on de novo protein design. Together with @HattoriLab , @sokrypton & @….

RT @Xinru71: Now online: We created de novo insulin receptor agonists using computational protein design! @EunheeChoi12 @XiaochenB @Preetha….

RT @Andrew_Akbashev: Nobel Prize is NOT about h-index or citations. It is about the emergence of big new fields. So many posts discuss Nob….

RT @paultkim_ipd: With David and the Baker Lab in the spotlight today, I wanted to share some insights into the @UWproteindesign and how it….