Jessica Jimenez
@Jcjimenez6
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sleep fellow, neurologist/neuroscientist @UCSF | MD PhD alumna of @Columbia | neural circuits, sleep, learning, and anxiety
San Francisco, CA
Joined September 2011
Excited for our work out in @NatComm! https://t.co/lnAWK8guPR vHPC shock neurons become synchronized in contextual fear memory retrieval, ^synchrony=^memory strength, & shock neurons in vCA1-BA>LHA. Dream team mdphd project w @drdrjack @selimchl in @Rene_Hen lab w @mazen_kheirbek
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Congrats to @Ale_LopezCruz in @zaknight lab, and all of the new @HHMINEWS Hanna Gray fellows! https://t.co/V2CzRLwYfi
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Thrilled to share our new paper in @Nature - "Understanding the neural code of stress to control anhedonia." A wonderful team effort with @_fxia, @VFascianelli and @StefanoFusi2. Check out the thread below. https://t.co/4dw0wZ09OU
nature.com
Nature - Examination of the neural activity in the basolateral amygdala and ventral CA1 of mice during tasks or rest following exposure to social stress reveals signatures of resilience and...
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I poured my soul into itā¦ || The anatomy of brainwashing | Science
science.org
Glymphatic-lymphatic brain cleansing may reveal new therapeutic strategies
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Did you know that the nervous system can help to build and repair bone? New work from @hollyingrahamSF identifies a key brain-derived hormone that repairs bone in both sexes and critically maintains bone density in lactating female mice https://t.co/yB5tlK0TDh
nature.com
Nature - A brain-derived hormone, CCN3, is newly identified to have a role as an osteoanabolic factor to build bone in lactating females and in the viability of offspring.
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Cerebrospinal fluid links the brain and peripheral sensory system and drives headache in migraine with aura! Weāre excited to share our newest article just published today in @ScienceMagazine . Please read along: https://t.co/ab3HuaTpYe
science.org
Classical migraine patients experience aura, which is transient neurological deficits associated with cortical spreading depression (CSD), preceding headache attacks. It is not currently understood...
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Excited to share our new study where we discovered a new form of B12 deficiency that cannot be detected on standard blood tests. (1/6) @samplease @neurores_ucsf @skondapavulur @Michael_S_Haney @AAsencor @EoinFlanagan14
science.org
An autoantibody targeting the transcobalamin receptor impairs vitamin B12 transport into the central nervous system.
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And beautiful cover art by @jvpluv - read more to learn about his discovery and mechanistic exploration of autoimmune B12 central deficiency
This week's new issue of #ScienceTranslationalMedicine is out! Protein "maps" in cerebrospinal fluid offer new markers for #AlzheimerDisease, a Viewpoint discusses new policies to overcome hurdles to drug repurposing in the U.S. and Europe, and more. https://t.co/1S0WBrtCxA
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Im incredibly honored to be selected as one of the 2024 McKnight Scholars
Congrats to MBIās @DrNancyPadilla on a three-year $225K McKnight Scholar Award for early-career neuroscientists in support of her project examining changes at the neurological level when the brain switches from cooperation to competition. Read more: https://t.co/3wKNIGJQ2E
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Excited to share my PhD work in @pgolshani 's lab designing and building low-cost miniature 2P microscopes with everyone! They cost < $10k USD (even at low production runs), are fitted with 2 on-board SiPM detectors, and are completely open-source! 1/5 https://t.co/LRof7MMKf7
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1/7 For the past decade, our team at Meta Reality Labs (previously CTRL-labs) has been dedicated to developing a neuromotor interface. Our goal is to address the Human Computer Interaction challenge of providing effortless, intuitive, and efficient input to computers.
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Thrilling @GreenJournal case by my @neurores_ucsf and @UCSFimaging colleagues @SumanthReddy_MD @saralahue (+Soonmee Cha)! If you ever find yourself whispering "please don't be neurosarcoidosis" reading a case challenge, this one is for you š
https://t.co/6Jh3TS1siA
neurology.org
The evaluation of patients with disseminated processes with CNS and osseous involvement is often challenging. A 22-year-old healthy man developed left-sided weakness, paresthesias, and neck pain over...
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New preprint from the lab by @_fxia in collaboration with @VFascianelli and @StefanoFusi2! Population dynamics in the amygdala can distinguish stress resilience and susceptibility, and modulation of vCA1-BLA inputs can rescue behavioral and neural signatures of susceptibility.
Check out our new preprint on neural signatures of stress susceptibility and resilience in the amygdala-ventral hippocampal network! https://t.co/sYSA8K5dkP Thread below š
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Check out our latest neurogenesis paper by @DrSebnemT, @attila_losonczy, and @AndresGrosmark. Adult-born granule cells facilitate remapping of spatial and non-spatial representations in the dentate gyrus: Neuron
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B12 deficiency can affect every part of the nervous system. But what if B12 levels in the blood do not reflect those in the brain? Check out our preprint on āTranscobalamin Receptor Autoantibodies in Central Vitamin B12 Deficiencyā:
medrxiv.org
Vitamin B12 is critical for hematopoiesis and myelination.[1][1] Deficiency can cause neurologic deficits including loss of coordination, spasticity, and cognitive decline.[2][2],[3][3],[4][4]...
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New paper from the lab out today! @jeremy_biane, @max_ladow and team describe how neural population dynamics in dorsal and ventral CA1 evolve with associative learning and outcome expectation. Full text here: https://t.co/lSMxx8zRGU
Tracking the same hippocampal dorsal CA1 and ventral CA1 neurons during odorāoutcome learning shows that initially odors elicited responses in dCA1, whereas odor responses in vCA1 emerged later and represented the outcome New from @mazen_kheirbek et al. https://t.co/LHYVzmd89n
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DM if you are a grad student, postdoc or faculty who finds yourself in need of an invitation to give an informal seminar at UCSF to justify a trip to CA. We donāt have funds to offer but can provide an invitation, other organizations may have fundsā¦
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So happy to share this case report now published from my medicine intern year- a testament to the amazing medicine and interdisciplinary efforts you see @UCSFMedicine! A rare case of giant cell myositis https://t.co/OmdybfcQEr
@UCSFIMChiefs @neurores_ucsf
casereports.bmj.com
Giant cell myositis (GCM) is a rare inflammatory myopathy associated with myasthenia gravis and thymoma. Here, we report on a woman in her late 50s with a history of myasthenia gravis, systemic lupus...
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Finally happy to unveil my postdoctoral paper on its final form, done under the guidance of @kaymtye and in colab with @BatraKanha @Cewu_Lu A few highlights: -A new dominance assay for mice -A new tool, AlphaTracker, to track multiple animals 1/n
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