Hallou Lab
@Hallou_Lab
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Group of Dr Adrien Hallou @KirOxford @UniofOxford | Biophysics & spatial biology of cell fate decisions & tissue dynamics | Alumnus @Cambridge_Uni @ENS_ULM
Oxford
Joined November 2023
Celebrating the 1st anniversary of @Hallou_Lab @KirOxford @UniofOxford 🥳🍾!! So grateful to be working with these amazing young scientists ! Watch this space in the next few weeks for: - Exciting new science ⚙️🧬💻🔬 - An official lab picture (minus🍕🍻😆) - Job openings 😉!
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Only a few days left for abstract submission at the brand new EMBO|EMBL Symposium Collectivity in living systems: emergence, function and evolution. We have stellar speakers in cell, animal collectives & beyond @priscaliberali @icouzin @ricard_sole
https://t.co/IcoQG69GJ3
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Our spatio-temporal map of lesion repair in the heart at single-cell resolution is now published in @NatureCVR. https://t.co/90dWoRfL9i We dissected dynamics of multicellular niches that control cardiac repair. See 🧵for highlights.
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Absolutely delighted to have been able to participate to this stimulating visit of the Franco-British Council @francobritish on Energy and Innovation, and to have been able to welcome the group @UniofOxford !
The Franco-British Council today starts a two-day programme of visits looking at energy collaboration between the UK and France. The first visit is to the National Energy System Operator @neso_energy which operates the flow and planning of Great Britain’s vast energy networks
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Now out in final form, check out our latest work on theca cell mechanics and compressive stress in ovarian follicles. Led by talented @AriktaB, this work will not be possible without the support of collaborators and @MBIsg. Congrats to team! #ProudPI
https://t.co/1jmNum574w
nature.com
Nature Communications - Maturation of functional eggs in mammalian follicles is crucial for ovarian physiology. Here, Biswas et al. report that compressive stress by contractile theca cells or...
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📣Announcing the 4th edition of the EMBL‑IBEC Conference on “Engineering Multicellular Systems”, taking place 11–13 March 2026 in Barcelona. Exploring organoids, mechanobiology, embryo models, organ-on-chip systems, multiomics and more. Abstracts open now! https://t.co/xZhuYMl5cW
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Nature research paper: Niche-specific dermal macrophage loss promotes skin capillary ageing https://t.co/aKXIQYXnGd
nature.com
Nature - Capillary-associated macrophages are selectively lost over time, contributing to impaired vascular repair and reduced tissue perfusion in older mice.
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Analysis of single-cell sequencing data from early ascidian embryos shows that gene expression is correlated for cells within the same embryo even after accounting for known sources of variation such as developmental time. 🔗 https://t.co/GWLRwiMplR
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Check out our latest work on using quantitative micro-elastography to study 3D ovarian tissue mechanics during ageing. Thanks to Anna, Matt, Ali and Brendan for making this happen. Kudos to interdisciplinary science! https://t.co/qlpS505Gx9
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I will also rember his enthusiasm when he told me one morning, just a few years ago, that he was quite excited to do his "1st single-cell RNA seq experiment" while he was queuing behind me at the ice machine! Vale Sir John!
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Sadened to learn about the passing of Sir John Gurdon. John was a true gentleman scientist. I remember how he took time to speak to me after my first talk as a postdoc @gurdoninstitute, asking deep and inqusitive questions and generously sharing advice and experimental protocols.
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Now out in its final form, with a new title "Mechanical control of cell fate decisions in the skin epidermis" and simulations/quantifications! See below for thread of how unbalanced tensions can bias fate choices in minimal 3D models of tissues/tumors!
nature.com
Nature Communications - The mechanisms underlying cell fate decisions often remain unclear. Here, the authors develop a 3D vertex-based model of complex fate choices in skin epidermis and propose a...
Happy to share the latest work from @DrPreetiSahuPhD, with @ASanchezDanes on the biomechanics of cell fate choices during tumor initiation! We implement/test a 3D vertex model with proliferation and fate choices for multilayered tissues! 🧵below (1/n) https://t.co/PeV7Qrro39
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I am delighted to share this new review in @NatureCancer that I co-author with @AnqiDong18 In which we discuss the different EMT tumor states and their implications for metastasis and cancer therapy.
NEW content online! Identification, functional insights and therapeutic targeting of EMT tumour states https://t.co/1g5x4td9Vc
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Our lab's first venture into understanding fluid formation in ovarian follicles. Excellent work led by Kim Whye Leong and Yuting Lou, highlighting the importance of interdisciplinary approaches in life science. Come hear their talk #MBIMPG2025 @MBIsg today! https://t.co/I47ry3gSUV
biorxiv.org
A key process during mammalian folliculogenesis is the formation of a fluid-filled antrum around the oocyte. While it is known that the antrum is critical for oocyte maturation and the eventual...
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‼️See below terrific opportunity for a postdoc post with a leading group in Oxford, super exciting science, now being applied to myeloid malignancies! 🔥🔥👇@UniofOxford @Ludwig_Cancer @ASH_hematology @CR_UK
Please share: we’re recruiting a postdoctoral fellow – applications open until September 15! To lead genomics data analysis of an exciting translational project in sAML cancer, supportive environment, and access to unique in-house technologies. https://t.co/plDpkuSAnW
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1/11 In @ScienceMagazine: A new perspective on how our intestines renew. Cells are not “pushed out” by crowding or die from apoptosis. Instead, cells play a mechanical tug-of-war, where weaker cells extrude, reframing gut renewal as force-regulated.
science.org
Cell extrusion is essential for homeostatic self-renewal of the intestinal epithelium. Extrusion is thought to be triggered by crowding-induced compression of cells at the intestinal villus tip. In...
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If you are looking for a PhD then this call is for you. The AfOx KTPS funds students from Africa to read for a full time PhD @UniofOxford Join us! My amazing supervisor @UdalovaLab has a computational project listed. Check it out here https://t.co/qnvAgas1Xq
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Platelets eating DNA? Check out this new wild new paper from @l_cmurphy in my colleague @beth_psaila's lab at @UniofOxford: https://t.co/ZIC7lCYhYY. Very excited to have Lauren join for a joint postdoc between our two labs to look at this in #zebrafish!
science.org
Platelets are anucleate blood cells vital for hemostasis and immunity. During cell death and aberrant mitosis, nucleated cells release DNA, resulting in “cell-free” DNA in plasma (cfDNA). An excess...
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(1/12) Over a year ago, we launched a new project to explore whether the tissue microenvironment could predict cellular behaviour and whether reprogramming might unlock new therapeutic avenues. 🧬 Spatial transcriptomics provides deep insights into tissue organisation. We
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An exciting opportunity to start an independent position as a research fellow in protozoan parasitology at Christ's College, Cambridge and the Department of Pathology: https://t.co/8XUY41ZcnE
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A slight change of pace from maternity leave to spend a fantastic few days with @francobritish for this years #francobritishyoungleaders seminar. Particularly grateful for all speakers and atendees acommodating the youngest member to make it possible for me to attend avec bébé.
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