An inflammatory sciences centre
@UniofOxford
@NDORMS
. Bridging discovery and clinical research, focused on the biology of tissue health and chronic disease.
Our Director of Research, Prof Michael Dustin, has been elected as a member of the US National Academy of Sciences for his contributions to molecular immunology. Congratulations to Mike on this tremendous achievement!
@MichaelLDustin
@OxfordMedSci
Kennedy researchers receive
@The_MRC
funding for projects spanning microbiome and arthritis, inflammasomes and B cells in autoimmune disease. Congratulations all!
@JelenaLab
@a_j_clarke
🎉 Congratulations to Prof Katja Simon who has been elected a Fellow of the Academy of Medical Sciences for her exceptional contribution to the advancement of medical science.
@acmedsci
@aksimonlab
New review from Profs Chris Buckley, Mark Coles and colleagues examines fibroblasts as immune regulators in different tissues and disease states.
@NatRevImmunol
@arthritisbham
And that’s a wrap on the
@KIROxford
Retreat! Thank you to all of our brilliant speakers for updating us on your vital and ground-breaking research. It was fantastic to be back together in-person again!
Congratulations to Audrey Gérard and her team, who received £1.5 million in funding from
@CR_UK
for a new project to unravel the coevolution between cancer and the immune system! 🎉
Read about Audrey's project ⬇️
@AGerardLab
Cornelia Heuberger successfully defended her D.Phil thesis entitled “Antigen presentation and T cell regulation by intestinal epithelial cells.”🎉
Congrats to Cornelia and her supervisor Fiona Powrie. Thank you to the examiners, Prof
@MichaelLDustin
& Prof G Frankel
@powrie_lab
Alina Janney successfully defended her D.Phil thesis entitled “Host-microbe interactions in inflammation-driven cancer”. 🎉
Congratulations to
@AlinaJanney
and her supervisor Fiona Powrie
@powrie_lab
.
Thank you to the examiners, Prof I Udalova
@UdalovaLab
and Dr L Carlin
A large-scale genetic study by a research team including Dr Luke Jostins suggests shared biological pathways contribute to irritable bowel syndrome and mental health disorders such as anxiety.
@lukejostins
@NatureGenet
Read more 👉
Congratulations to
@doro_berthold
,
@UdalovaLab
, for successfully defending her Thesis entitled "Myeloid cells at the onset of colitis in the context of IRF5 deficiency" 🥂🎉
Thank you to examiners Prof Simmons and Prof Hidalgo
Congratulations to
@nanaborsa
and Edward Jenkins on being awarded Sir Henry Wellcome Postdoctoral Fellowships, which give recently qualified postdoctoral researchers the opportunity to start independent research careers! 🎉
We've launched a new single cell facility!🎉
This will provide the technology, training, and expertise, for researchers to isolate cells and undertake genomic analysis at a single cell level🔬
Read more from
@snsansom
and
@irina_neutro
(
@UdalovaLab
) below
📽️We had an exciting day yesterday with a film production team onsite! 📽️
@theAliceRoberts
caught up with Fiona Powrie & Claire Pearson from
@powrie_lab
to understand how our gut microbiome affects our immune system. 🦠
Congratulations to Audrey Gérard, Jelena Bezbradica Mirkovic and Brian Marsden who have been awarded the title of Associate Professor, together with other senior researchers
@ndorms
.
@JelenaLab
@TheKennedyTrust
Congratulations to Elizabeth (Libby) Jennings who successfully defended her DPhil thesis yesterday, titled 'the role of the tissue microenvironment in inflammatory bowel disease'! 🎉🥳
@Lib_Jennings
@LabMidwood
@powrie_lab
Congratulations to Kennedy researchers who received
@BBSRC
funding to study the link between maladaptive neutrophil development & chronic inflammation! 🎉
Read about how their research could lead to neutrophil-based therapies for chronic conditions. 👇
🎉 Congratulations to Professor Irina Udalova, who has been appointed to the MRC's Infections and Immunity Board! 🎉
During her two-year tenure, Irina will support the board's strategy to fund research into human pathogens and the immune system.
Welcome to the Kennedy Institute,
@CalliDendrou
!
Calli is a leader in cross-disease multiomics for studying inflammatory disease 💻
She is an advocate for diversity in science & was elected by the
@NDMOxford
as an Inspiring Woman of the Year in 2022 👩🔬
Prof Paul Klenerman
@PKlenermanLab
is presenting 'Taking Tmic' Monday at 12pm. Make sure to join us on Zoom!
Hosted by
@arthritisbham
Open to all Oxford University members, register using a valid Oxford email address via the link below ⬇️
‘Emma Carter-Biggs always makes time to help, and has a stash of chocolates and a hug ready or when you’re struggling. Plus she basically keeps the institute running.’
@KIROxford
A huge congratulations to Suzanne Engelen, MD
@LabMonaco
for successfully defending her thesis entitled "The role of Natural Killer T cells in atherosclerosis" last week! 🎉
Thank you to examiners
@JelenaLab
and Prof M P J De Winther
We are delighted to welcome Dr Adrien Hallou as a group leader in tissue biology!
Adrien's lab will study the role of mechanical forces on cell fate decisions & tissue dynamics in inflammatory diseases like psoriasis & atopic dermatitis
Welcome, Adrien!
Lots of our scientists work with industry to solve biological challenges - this week we're highlighting their stories!
Read Dr Lakshanie C Wickramasinghe's journey working with
@JanssenUK
to discover treatments for the eye disease anterior uveitis. 🔬👁️
In a major boost to inflammatory & musculoskeletal disease research, two new professorships in translational medicine will be held by Professor Chris Buckley & Professor Tonia Vincent. 🎉🎉
We are so grateful to the
@TheKennedyTrust
for this generous gift!
Read more 👇
Research into inflammatory and musculoskeletal diseases at
@KirOxford
has received a major boost following the endowment of two professorships in translational medicine. 🎉
We're extremely grateful to
@TheKennedyTrust
for securing these important posts.
Read more ⬇️
We are delighted to welcome
@FranzeProgatzky
as a new group leader in tissue biology!
Fränze studies the role of glial cells in the gut & lungs. She is an advocate of positive research culture & sustainable science.🍃
Read more about Fränze here! ⬇️
We are proud to announce that we are now a period positive Institute! Staff and students can now find period products, free of charge, in toilets around the building.
#periodpositive
@totmorganic
A research team led by Prof Irina Udalova has found a new molecular pathway that regulates pro-inflammatory macrophage activity that could be targeted by experimental drug, defactinib.
On Monday 4 March, Prof Mala Maini joins us to talk about "Tissue T cells: Life in Lockdown in Liver and Lung". Don't miss it!
🕚12:00-13:00
🏢Kennedy Lecture Theatre
💻Oxford Talks
"Some hospital CEOs say you don't need to do research to deliver a good service. But if you want to deliver an excellent service you need to combine clinical academia with discovery science, in the way we do at the Kennedy; it produces amazing stuff." Prof Chris Buckley.
Dingxi Zhou successfully defended his D.Phil thesis entitled “Autophagy's Roles in the Activation and Ageing of CD4+ T Cells”👏
Congratulations to Dingxi and his supervisor Prof Katja Simon (
@aksimonlab
). Thank you to the examiners, Prof T Dong and Prof F Macian-Juan.
Congratulations Barbora on winning 'best final year presentation' at this week's Kennedy Institute Student Symposium!! 🥳
Well done to all our amazing students, the standard of presentation was fantastic. 👩🔬➡️🌟
Many congratulations to my dear friend
@capyBara_bs
for winning the best presentation of final year PhD students. We are very happy for you! Thanks
@YavuzYaziciogl1
for the blurry picture 😏
@FabiAlexFischer
Some happy time at
@KirOxford
student symposium
A new study, published in
@Nature
, reveals how T cells gain and maintain tolerance to gut bacteria.
Findings could be used to design better therapies for patients with inflammatory diseases of the gut.
Read more! ⬇️
@haemyisu
@emilyethornton
Welcome to our new PI
@yluo86
!
Yang's lab is leading the investigation into how genetic variations contribute to diseases of the immune system.
Read more about how she plans to boost data science research at the Kennedy Institute below ⬇️
Using transcriptional and chromatin profiling, Prof Irina Udalova and colleagues identify transcription factor networks that control neutrophil maturation, effector responses and survival during inflammation
@NatImmunol
Congratulations to Arnon group student
@RichmondNiamh
who successfully defended her Thesis entitled 'Pulmonary cell signals mediating resident memory B cell responses to influenza rechallenge' this morning! 🎉👏
Thank you to examiners
@AhmedNHegazy1
and Dr Audrey Gerard
Today we recognised our dedicated support staff with some long-service awards (& tea and strawberries)! 👏🎉
Our science is enabled by the essential financial, facilities, and administrative support along with so many other services that keep the institute running.
Very happy to share that I passed my PhD viva yesterday! Thanks to the most amazing lab for the past 4 years and the outstanding supervision by
@JelenaLab
since I started here! A big thanks also to
@BenediktKessler
and
@FelixRandow
for the super helpful discussion and feedback!
New research from
@KusumbeLab
suggests vasculature attrition, including pericyte to fibroblast differentiation, is an early hallmark of tissue aging in multiple organs
@ScienceAdvances
On Thursday Prof Bernd Bodenmiller (
@BodenmillerLab
) joins us via Zoom as part of our external seminar series.
🗓️Thursday 29th September
🕛12-1:30pm
🖥️Zoom (registration info below)
Big shoutout from Prof Tonia Vincent to the Institute’s histology lab for being so amazing, supporting everybody so well, and fostering a great working culture!
Dr
@domdenardo
, hosted by
@JelenaLab
, will be joining us virtually on Monday to tell us all about "Discovering new mechanisms controlling cGAS-STING signalling" at the earlier time of 9am 🕘
Open to all Oxford University members
Registration info below ⬇️
Anna Marzeda successfully defended their D.Phil thesis entitled “Endogenous triggers of inflammation in the pathogenesis of autoimmunity”. Congratulations to Anna and their supervisor Kim Midwood. Thank you to the examiners, Prof R O Williams and Dr M S Kurowska-Stolarska
Join us on Monday for our first seminar of 2022, presented by Prof Joerg Enderlein!
@JoergEnderlein
Hosted by
@FritzscheLab
🗓️Monday 24th January
🕛12pm
Via Zoom, registration required using the link below, open to all Oxford University members.
@CJStewart7
joins us on Monday to talk about “Diet-microbe-host interaction in early life”
He is hosted by
@powrie_lab
🗓️Monday 5th September
🕛12pm
🗺️The Kennedy Institute Lecture Theatre
Open to all Oxford University Members ⬇️
New review from Profs Midwood and Buckley examines how the tissue microenvironment and extracellular matrix affect joint inflammation and tissue damage in rheumatoid arthritis.
@NatRevRheumatol
@arthritisbham
DPhil student
@Ruthnanje
visited Buckingham Palace to celebrate 60 years of Kenya's independence 🇰🇪, & met King Charles! 👑
In this article, Ruth speaks about
@Africa_Oxford
&
@oxfordafrica
removing barriers for African students to study at Oxford.
The
@OxZCoE
is more than a bioimaging facility - it's a space where
@zeiss_micro
R&D & Oxford’s researchers create the next generation of imaging technologies. 🔬
🗓️ Inaugural opening event: 21 Feb 2024
⬇️ Learn what this partnership is achieving!
We are excited to launch the Oxford-Zeiss Centre for Excellence in partnership with
@IrdmOxford
to develop and apply the latest approaches in advanced imaging
@KirOxford
and
@IdrmOxford
has launched the Oxford-Zeiss Centre of Excellence! The Centre will provide state-of-the-art imaging technologies to lead future discoveries in global health and disease.
Our August cover shows sagittal plane confocal image of a naive knee from CX3CR1-eGFP Ly6G-tdTomato double reporter mouse containing resident
#macrophages
and no neutrophils. From Zec et al.
@UdalovaLab
()
Read JEM’s August Issue:
Click the link below to read about how the arthritis therapy programme, led by our director of clinical research
@arthritisbham
, aims to speed up the discovery of new treatments for inflammatory disease.
Our external seminar this week is on Thursday at 1pm when
@AhmedNHegazy1
joins us in out lecture theatre!
🗓️Thursday 13th October
🕐13:00 - 14:00
🗺️ The Kennedy Institute Lecture Theatre
Open to all Oxford University members ⬇️
Prof Claudia Monaco and collaborators have been awarded $7.5 million by the
@FondationLeducq
to advance immunotherapy as a treatment for cardiovascular disease! 🎉
Read more below ⬇️
@LabMonaco
Tomorrow Dr Leo Lahti (University of Turku) is presenting 'Emerging topics in microbiome data science' in our Lecture Theatre. This will be our first in person ad-hoc seminar this year, be sure to come along if you can! Also on Zoom
@antagomir
1:30-2:30pm
New research from
@powrie_lab
and colleagues reveals IL-1-driven stromal cell–neutrophil interactions define a subset of patients with therapy non-responsive
#IBD
.
We are recruiting a
#postdoc
to join the lab of
@FranzeProgatzky
!
Do you:
✅have a PhD in immunology/neurobiology?
✅want to study how peripheral glial cells regulate inflammation in the lung?
Apply by 13 Feb! ⬇️
New research from Dr Fiona Watt and Prof Tonia Vincent
@OACentreOxford
reveals potential ways to measure and predict how likely someone is to develop osteoarthritis after a knee injury.
@VersusArthritis
Congratulations
@a_j_clarke
for winning the Emerging Leaders Prize for lupus research last week! 👏
Alex's research aims to understand the fundamental causes of lupus, with the objective of identifying novel treatment targets. Read more below ⬇️
Congratulations to
@MichaelLDustin
who was elected as a Fellow of The Royal Society
@royalsociety
on Wednesday for his contribution to immunology research. 🎉
Using 3D and two-photon microscopy, the Arnon lab show how resident memory B cells relocate and boost antibody production at infected sites of the lung during flu reinfection.
@TheKennedyTrust
@ImmunityCP
Read more via the link below ⬇️
The Oxford-ZEISS Centre of Excellence in Biomedical Imaging officially opened this week! ✨🔬✨
The centre promises to deliver the latest imaging technologies & analysis approaches to advance the study of health & disease.
Read more! ⬇️
@zeiss_micro
Congratulations to Clinical DPhil student Pragash Kamalathevan on successfully defending his DPhil Thesis! 👏
Thank you to examiners Prof Andy Clark and Dr Stephanie Dakin
2nd year RACE PhD students, Jean-Baptiste Richard, Bogdan Didov, and Annabelle Ferguson, gave excellent presentations about their projects and responded well to some probing questions!
Today we met with our patient partners to ensure we integrate their perspective and experience into Kennedy research.
Here PhD student
@juliasalafranca
discusses the factors that can make partnerships successful. Thanks to everyone for your insights!
We’re looking for an enthusiastic and proactive Strategic Projects Manager at
@KIROxford
. Director of the Kennedy Institute, Prof Fiona Powrie (
@powrie_lab
), tells us more about the role, and the work we do here.
Applications close on 30 September ➡️
Applications now open for
@TheKennedyTrust
Prize 4-year DPhil studentships
@KirOxford
. Multidisciplinary clinical and non-clinical projects including immune cell fate & function, advanced imaging, inflammation, microbiome, arthritis and cancer
📢 The
@powrie_lab
is
#hiring
!
Looking for a
#postdoc
position in immunology? Interested in studying the immune response in the intestine & how genetic mutations affect microbial populations?
Apply by 21st July! 👇
It's the moment we've all been waiting for!! ✨
(Watching our Head of Operations impersonate Hugh Grant for 'NDORMS Actually 🎁')
Sound on 🔊 for this
#FridayFun
from our own halls!
In his inaugural article in the Proceedings of the National Academy of Sciences as an NAS member, Prof
@MichaelLDustin
and
@AudunKvalvaag
have explained how messages are passed across the immunological synapse.
Read more below⬇️
Merry Christmas and a Happy New Year from all of us at The Kennedy Institute! 🎄🎁
We're closed from today until the 3rd January and look forward to another great year of research in 2023!
We are advertising for a new group leader to join the Arthritis Therapy Acceleration Programme
@KirOxford
@InflamAge_UoB
to lead on computational cross-disease analysis of immune-mediated inflammatory disease.
👉
Closes midday 5 July. Please retweet!
‘You’ve been incredible throughout the pandemic! You’ve cared for loved ones, you’ve supported each other, all the while producing amazing science that has an impact on the world’s biggest health issues!’
Prof Fiona Powrie to our staff and students
Thank you and congrats to Klara Piletič
@pileticklara
for starting the day with her research on adipocyte autophagy and going on winning the short talk prize
@ndorms
On Monday
@ActonLab
joins us to talk about "Mechanical Control of Immune Function" hosted by
@ColesBuckleyLab
🗓️ Mon 6th Feb
🕛 12:00-13:00
🗺️ Kennedy Lecture Theatre or Zoom
Open to all Oxford University members
'It lets me see how the conditions that I study affect people in the real world'
DPhil student
@juliasalafranca
involves patient perspectives in her research - read this interview to learn why she finds their guidance so valuable. 👇
We are incredibly proud of our Director, Prof Fiona Powrie, who has been recognised in the 2022 Queen’s Birthday Honours List with a DBE for services to Medical Science.
In a double feat this week, well done to our Histo team for their image being shortlisted at the Oxford-Zeiss CoE launch event image competition! They have beautifully captured a mouse tail stained with Masson’s trichrome!
#bioart
@zeiss_micro
Here at the Kennedy Institute we run programmes to support early career researchers including our Career Development Programme, supported by the
@TheKennedyTrust
, which helps researchers launch their own independent labs
@a_j_clarke
@JelenaLab
@WannAngus