Eva Maria Novoa
@EvaMariaNovoa
Followers
1K
Following
768
Media
10
Statuses
353
Group Leader -Epitranscriptomics & RNA Dynamics @CRGenomica. Biochemist and bioinformatician. #RNAmods #nanopore #ribosome. Mom of 3. Piano, beach vball, hiking
Barcelona, Spain
Joined September 2015
Fresh preprint from the @NovoaLab!😀📌 Do you want to barcode up to 96 #RNA samples in your #nanopore flowcells? How well do RNA #modification-aware models perform? What if there is #noBasecallingModel for your modification-of-interest? Find it out here!😊 https://t.co/PwAWfhy9ra
biorxiv.org
Nanopore direct RNA sequencing (DRS) holds promise for advancing our understanding of the epitranscriptome by detecting RNA modifications in native RNA molecules. Recently, Oxford Nanopore Technolo...
0
10
30
I am so incredibly excited to share our latest work, on the exploration of #RNA secondary structure ensembles and discovery of RNA regulatory structural switches in bacteria and human cells, out today in @NatureBiotech: https://t.co/tqiilEGJkp. A short tread! (1/n)
nature.com
Nature Biotechnology - Transcriptome-scale maps of RNA secondary structure ensembles in living cells detect candidate RNA structural switches.
8
44
186
New postdoc opening @UNSW in RNA biology and T cell immunity 🥼🧬🧫. Use molecular biology, nanopore sequencing, and in vivo models to uncover the regulatory drivers of adaptive immunity. Apply 👉
0
7
16
As a co-founder of 23andMe, with all the recent news I felt it was time to express my views on the company, after witnessing the downfall of an idea and brand that could have become the world’s leading digital health platform. The idea for 23andMe came to me after years working
67
148
685
Truly honored to receive this prize. This would have not been possible without the support from my wonderful family, all past and present @NovoaLab members, and our larger @CRGenomica family. Thanks for your continuous support! ❤️
📢Nous guanyadors dels Premis Nacionals de Recerca de Catalunya❗ 🎖Núria Sebastián Gallés, Premi Nacional de Recerca 2024 (@UPFBarcelona) 🎖@EvaMariaNovoa, PNR al Talent Jove 2024 ex aequo (@CRGenomica) 🎖@ros_xavi, PNR al Talent Jove 2024 ex aequo (@UniBarcelona) L'enhorabona!
0
1
27
I’m excited to share my work over the last few years with @JD_Buenrostro! Chronic inflammation creates an epigenetic memory in colonic stem cells, priming them for tumor growth: https://t.co/JPFKNYY1NI. Here’s a walkthrough of what we found (🧵)
biorxiv.org
Chronic inflammation is a well-established risk factor for cancer, but the underlying molecular mechanisms remain unclear. Using a mouse model of colitis, we demonstrate that colonic stem cells...
5
37
182
How has native RNA sequencing contributed to epitranscriptomic research? This is one of the main questions we addressed in our recent review by @EvaMariaNovoa and I now live in @MolecularCell
https://t.co/tI3c9EbrKd
2
16
68
Where RNA Science Meets AI, May 4–8, 2025, Ascona. Invited speakers: @OliverStegle @fabian_theis @fiddle @EvaMariaNovoa @BTreutlein @satijalab @RivasElenaRivas @RouskinLab @YosephBarash @gagneurlab, Rhiju Das, Karla Neugebauer, Jernej Ule Registration open,
1
9
36
Tweetorial by Gregor available here:
VERY excited to share SeqTagger with the world! If you want to learn more about our super-fast and accurate demultiplexing tool for direct RNA-sequencing (DRS), check out the thread below. https://t.co/eJFT76dwwI (1/15) 🧵
0
0
0
Very happy to share our SeqTagger work, led by the super-team of @GDiensthuber and #Leszek, to barcode and demultiplex #directRNA @nanopore data - also works with #RNA004 data! Code available in GitHub, feedback very welcome! :-)
biorxiv.org
Nanopore direct RNA sequencing (DRS) enables direct measurement of RNA molecules, including their native RNA modifications, without prior conversion to cDNA. However, commercial methods for molecular...
1
14
56
Into (r)RNA modifications? Check out the new review article by @EvaMariaNovoa and me, out today in @TrendsCellBio!
1
14
55
💥Cheeky 'little' update from @GencodeGenes v47, almost doubling the number of #lncRNA genes & ~4x more lncRNA transcripts. This was highlighted by @1QINGWANG when observing the greater quality of our reference-guided de novo TxOme assemblies from deep direct RNA sequencing data
3
40
117
thanks to all collaborators for making this possible! @sonia_cruciani #LaiaLlovera, @MorghanLucas @RebecaenTandem, #CorneliusPauli, #DanielHeid, #ThomasMuley, #MarcAndreSchneider, #LauraKlotz, #MichaelAllgaeuer, #RubenLattuca, @LafontaineLab @LabTidow
0
1
7
Interested in #rRNA #modifications? Pls take a look at our latest preprint, a work beautifully led by @IvanBeki, examining rRNA mod #heterogeneity across tissues, cell types, developmental stages and disease. PS. they also show promise as #biomarkers!
biorxiv.org
Mammalian ribosomal RNA (rRNA) molecules are highly abundant RNAs, decorated with over 220 rRNA modifications. Previous works have shown that some rRNA modification types can be dynamically regulat...
1
23
74
La Dra. Núria Montserrat, investigadora principal a l'#IBEC, ha estat escollida per liderar la Conselleria de Recerca i Universitats del nou govern de la Generalitat de Catalunya. @icreacommunity @nmontlab Moltes felicitats, Nuria! https://t.co/a3ApCeLOlC
ibecbarcelona.eu
L’Institut de Bioenginyeria de Catalunya (IBEC), centre CERCA, es congratula en anunciar que la Dra. Núria Montserrat, investigadora principal al nostre institut, ha estat escollida per liderar la...
4
17
94
Congratulations to the five #BISTCommunity researchers for their #ERCPoC grants in the latest @ERC_Research call: 🏅Eva Novoa & Luis Serrano @CRGenomica 🏅Gerasimos Konstantatos @ICFOnians 🏅Marcos García Suero @ICIQchem 🏅Samuel Sánchez @IBECBarcelona ➡️ https://t.co/KKcpNCmg0z
1
7
26
An early Xmas present is seeing Nano-tRNAseq, a @nanopore method I developed during my PhD with #LeszekPryszcz, available as an end-to-end service and future kit by @ImmaginaBiotech, with a few upgrades like multiplexing thanks to @NovoaLab. More info here
immaginabiotech.com
nano-tRNAseq, the groundbreaking technology that allows for quantification of tRNA and detection of chemical modifications. Learn more!
2
12
83
POST #3. I am extremely happy and excited to have become an @EMBO_YIP member. It is a wonderful programme to support young PIs, including #support to facilitate parents with children attend to #conferences (e.g. covering partner & child travel costs). More of this is needed!
I have decided to post a bit about some experiences as #femalePI, as I think that some #awareness needs to be made, and some things still need to #change. I will be sharing some good and not-so-good experiences. Hope this is useful to improve some things !!! 🙂 Feedback welcome!
2
1
30
Pre-announcement of a CNRS tenure-track position 2024 “RNA Modifications” at the Centre for Integrative Biology (CBI), Toulouse, France @CNRS tenure-track positions/Junior Professor Chairs to recruit outstanding early-career candidates will open soon (March 2024)
5
45
47