Denis LJ Lafontaine
@LafontaineLab
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RNA Molecular Biology Laboratory - Université Libre de Bruxelles - Ribosome biogenesis, RNA processing, RNA modification, nucleolus, cancer, ribosomopathy
Brussels, Belgium
Joined January 2013
RT @LaskerFDN: Combining sequencing and imaging, @sofiquinodoz maps the spatiotemporal dynamics of rRNA processing, demonstrating how rRNA….
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RT @RNAJournal: Mice with cardiomyocyte-specific knockout of #YTHDF3 subjected to #cardiac stress had no increase in protein synthesis or c….
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RT @hbozhao: Our tour de force into the nucleolar world — a stunning exploration of spatial organization and the functional choreography of….
nature.com
Nature - Spatially segregated rRNA processing dictates nucleolar morphology and drives outward progression of pre-ribosomal RNA through nucleolar phases.
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RT @omenndarlingbio: Now on the Princeton Engineering and ODBI sites, a new mapping tool that allows researchers to peer deep into cells' i….
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RT @RNAJournal: RNase L cleaves most tRNAs in the anticodon loops into various tRNA-derived RNAs (tDRs) including 5'-tDRAla that shows a tr….
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RT @KotaroFujii1: Excited to share our recent work, which addressed a mechanism by which the eukaryotic ribosomes increase the fidelity of….
academic.oup.com
Abstract. Eukaryotic ribosomes exhibit higher mRNA translation fidelity than prokaryotic ribosomes, partly due to eukaryote-specific ribosomal RNA (rRNA) i
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RT @Translacore: A PhD position is available to decipher the modus operandi of ribosome-inactivating proteins at Maria Curie-Skłodowska Uni….
translacore.eu
Job offer in molecular biology and structural biology. PhD-STUDENT SCHOLARSHIP (for a period of 25 months, with the possibility of extension by 1 yea
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RT @jingdongcheng: We are thrilled to share our exciting collaboration with @GreenLabJHMI , showing that RIOK3 specifically recognizes ub….
cell.com
Huang et al. identify a pathway for stress-induced 40S ribosome degradation: 40S ribosomes ubiquitylated by RNF10 are subsequently bound by the atypical kinase RIOK3, which mediates their degradation...
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RT @MolecularCell: Charting the epitranscriptomic landscape across RNA biotypes using native RNA nanopore sequencing .
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RT @SusanBaserga: A role for the kinetochore protein, NUF2, in ribosome biogenesis | Molecular Biology of the Cell .
molbiolcell.org
Ribosome biogenesis (RB) is an intricate and evolutionarily conserved process that takes place mainly in the nucleolus and is required for eukaryotic cells to maintain homeostasis, grow in size, and...
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RT @MolecularCell: Online Now: Epitranscriptomic rRNA fingerprinting reveals tissue-of-origin and tumor-specific signatures .
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Discover how unique ribosome fingerprints could revolutionize early cancer detection with non-invasive, portable scanners able to detect cancer with near-perfect accuracy. #RNA.#CancerResearch #EarlyDetection #Ribosome #Genomics #NanoporeSequencing
science-tldr.com
Discover how unique ribosome fingerprints could revolutionize early cancer detection with non-invasive, portable scanners able to detect cancer with near-perfect accuracy.
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RT @MolecularCell: Online Now: Structural dynamics of human ribosomes in situ reconstructed by exhaustive high-resolution template matching….
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RT @FortesLab: Amazing ribosomes and. incredible cytokines 😯👇.P-stalk ribosomes act as master regulators of cytokine-mediated processes:….
cell.com
Cytokines remodel the ribosome to incorporate the P-stalk, therefore altering the translation of mRNAs involved in cytokine responses.
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RT @ErikDassi: I have an open 12-month #postdoc position (net salary approx 2100€/month) in my lab to work on a fully funded collaborative….
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RT @RNA_julie: Delighted to co-supervise 2 advertised @BBSRCWhiteRose PhD projects 1- lncRNA function in human papillomavirus life cycle (l….
findaphd.com
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