Stirling Churchman
@fiddle
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@HMSgenetics professor. Interested in RNA dynamics across the cell esp. nuclear transcription and splicing and mitochondrial gene expression. (she/her)
Cambridge, MA
Joined November 2007
I'm thrilled to see the cover of @NatureSMB this month! My sibling Leidy Churchman made this special painting to illustrate our latest work on the packaging of mitochondrial DNA. Both works are nicely described in the "Musings on art and science" editorial.
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Happy to share our new review!.
To launch the collection, our review "The regulation and function of post-transcriptional RNA splicing" by Karine Choquet, @inespatop & Stirling Churchman @fiddle ( will be free for 1 month.
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I wrote this @WSJopinion piece with my father-in-law, Jack Strominger. "Science Suffers With Trump's Funding Freeze". America’s scientific enterprise demands reliable stewardship, not destabilizing political intervention. Please RT!
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RT @MolecularCell: RNA polymerases reshape chromatin architecture and couple transcription on individual fibers htt….
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RT @MolecularCell: Online Now: RNA polymerases reshape chromatin architecture and couple transcription on individual fibers .
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Congratulations, and many thanks to all who participated including @mtcicero26 @rsisaac. Another wonderful and fruitful collaboration with @stergachislab!.
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I’m thrilled to share our latest paper analyzing RNA polymerase globally at single-molecule resolution that provides a glimpse into the vast potential of single-molecule genomics. See tweets below for the overview, and read the paper for the full story!
How does Pol II navigate the crowded, complex chromatin environment, surrounded by nucleosomes and other transcriptional activity? We are excited to share our preprint, a fantastic collaboration with @stergachislab, led by Tommy Tullius @mtcicero26.(1/5).
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RT @LCochella: Our department @JohnsHopkinsMBG ( is hiring!.Join us to start your independent lab in a collegial a….
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RT @FujimoriLabUCSF: Check out @biochem_bri 's tweetorial for our latest: Inhibition of the mitochondrial ribosome by oxazolidinone and ph….
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A great opportunity to work under a brilliant and kind mentor!.
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@stephenfloor @MolecularCell Congratulations to all the authors! . Co-firsts: @robertietswaart @BrendanSmalec Albert Wu . @karine_choquet @ErikMcshane @DrDrJowhar Chantal Gueler @Autum_BaxterKoe @_emmarosewest Becky Fu @LukeGilbertSF @stephenfloor.
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🎉Our paper quantifying how RNA flows across subcellular compartments is published! 🎉. Read more in the preprint thread ⬇️ The paper contains an improved analysis of RNA flow rates and new collaborative work on DDX3X with @stephenfloor . @MolecularCell.
How does RNA flow through the cell? From their synthesis, chromatin release, nuclear export, ribosome engagement, and eventual degradation, we quantified the lives of human transcripts genome-wide. (1/7). See @BrendanSmalec and @robertietswaart ‘s preprint.
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RT @MoffittLab: So excited to announce our new method for multiplexed RNA imaging in bacterial cells: bacterial-MERFISH! A huge congratulat….
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Some of the highest expressed genes in our genomes are encoded by mitochondrial DNA. To understand how and why, we developed new methods that uncover the many quirks of mtDNA expression. Find out what we learned in our recent review by @ErikMcshane and me.
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