Oliver
@Eickelberg_MD
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Pulmonary physician-scientist, author, wildlife photographer. News from science, medicine, nature. Private account, views and opinions are my own. Dortmund-born
Pittsburgh, PA; Jackson, WY
Joined May 2014
Honored and happy to attend the annual @PittTweet Faculty Honors Convocation last week at Soldiers and Sailors Memorial Hall to receive @Simmons_ILD Chair. Beautiful day in #Pittsburgh with lots of admired colleagues and friends. Kudos and thanks to entire @PACCM team present.
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Why fundamental research is fundamental to progress, seeding major breakthroughs Editorial @Nature this week And 7 basic science discoveries that changed the world https://t.co/0YrKabc7ff
https://t.co/SM11QSJhWz
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This is incredibly beautiful!!
This October I’m drawing 1 molecule a day inspired by proteins in pdb @buildmodels Day 5 Prompt DEER Pdb 4YXH Two molecules of a deer prion protein decorate its head. Misfolded prions can make other prions to misfold causing neurodegenerative diseases in mammals. Next: PIERCE
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This bird just found out that golf balls bounce on concrete, and he’s having the time of his life 😂 https://t.co/VH9mzuYvyF
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I was curious to know how many times @NobelPrize laureates in physics were nominated before winning... so I wrote a little code to figure it out. Looks like the median is 17 but there is heavy tail. Incredible that Gell-Mann was nominated 129x before winning!
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A species of lungfish found in South America has claimed the title of the animal with the biggest genome sequenced so far. Learn more on #WorldAnimalDay: https://t.co/yXmctCX6PA
@NewsfromScience
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Viral AlphaFold Database dropped! NCBI RefSeq → 647,000 viral protein seqs MMseqs2 → ~117,000 clusters AlphaFold2 → 26,962 monomers AlphaFold-Multimer → 26,754 homodimers Foldseek → 12,894 structural clusters Enjoy.
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Exercise delays brain aging through muscle-brain crosstalk. The younger your muscles, the younger your brain.
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How can we study the effects of radiation on immune cells in #cancer? Using innovative human pancreatic tumor models, @joschakraske @science_wallet @peterhuber_hd @DKFZ @uniklinik_hd reveal photon and particle radiotherapy induce signals—grouped as modules—that attract immune
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🚨 New publication! 🚨In this perspective published in @JCI_insight, previous APSA Presidents and Executive Committee members highlight key APSA milestones in strengthening the physician-scientist community, including 20 years of the joint ASCI/AAP/APSA annual meeting!
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A compelling illustration of the difference between mRNA abundance, ribosome density and protein abundance.
A cancer therapy targeting the interaction between metabolism & protein synthesis. Dietary restriction of arginine and proline depletes polyamines, which in turn causes ribosome stalling at codons with A in the third position. This shifts the balances towards cell ...
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An open letter to the NIH: Value and costs in publishing Here we share our response to the NIH’s request for information on maximizing research funds by limiting allowable publishing costs: https://t.co/vnnqsJoirO
#AcademicPublishing #ScholarlyPublishing #OpenAccess
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BIG news! Fat Bear Week will take place from September 23-30. The chubby cubby appetizer, Fat Bear Junior, will kick off on September 18-19. Stay tuned for bracket reveals, bear bios, and more details.
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In this Review, Akiko Iwasaki @VirusesImmunity & authors @YaleMed discuss the role of complement in long COVID pathogenesis https://t.co/3UZnzK0aG3
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Glioblastoma — it’s starting to gel. @ErinAkins1 @kumarlabucb @ManishKAghi @UCBerkeley identify candidate glioblastoma therapeutic targets among M2 macrophage-secreted factors using multi-omics analysis of 3D cell culture and patient biopsies: https://t.co/QAHNNXvPYf The
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If it’s one thing we’ve learned hiking, it's the early bird that gets the face full of spiderwebs.
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It has long been believed that skin and hair follicles are maintained by compartmentalized stem cells. This issue’s cover features work by @ElnazGhotbi, Lu Q. Le & team @UVA, @MedicineUVA on the contribution of hair follicle epithelial stem cells to interfollicular epidermis
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When you get your DNA results back and find out you’re 3% frog.
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What's the optimal number of steps of physical activity that is associated with multiple (9) favorable outcomes? The largest, systematic review of 57 studies, 35 cohorts. 7,000 steps is clinically meaningful; some benefit also seen for 4,000 steps cf 2,000 steps @TheLancet
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