Damien Huzard
@DHuzard
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| Neuro-Physio-Behaviorist | | Jokes are mine | Quotes are referenced From academia to industry
Montpellier, France
Joined September 2016
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Last Seen Profiles
Pinned Tweet
is OFFICIALY launched today! PLEASE SHARE the info ! It is for ALL people interested to share/ask/discuss any details and pro-tips about behavioural testing ! Special focus on homecage-monitoring systems !!
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Join my lab:
- No "desired" results (and no anthropomorphism)!
- Not playing the Publish-or-Perish game.
-Negative results are welcome.
- Caring about ethics and the planet.
- No passive-aggressivity, No bullying
Just one drawback, I have no lab...
(I'M LOOKING FOR A JOB THOUGH)
"In some labs". The entire culture of modern science fosters a dynamic where people who produce desired results are favored, regardless of the quality of the work or even research integrity. You can't avoid that just by joining a different lab.
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What a pleasure, when your
@DeepLabCut
tracking works! Now let's play with keypoint-MoSeq and dlc2action ! Tahnk you
@Cajal_Training
to organize this Neurokit!
@trackingplumes
@TrackingActions
@taunbot
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New study in
@NatureNeuro
reveals that early changes in touch processing in mice predict later autism-like behaviors. This could pave the way for earlier detection and intervention strategies for ASD.
#AutismResearch
#Neuroscience
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I am delighted to share my new paper, out in
@ScienceAdvances
: we show that a specialized population of sensory neurons is regulating social interaction in groups of mice. Introducing the C-LTMRs as encoding pleasant/affective touch. (1/11)
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#FENS2020
is the new
#Netflix
!
#FENSathome
and ultimate
#couplegoal
.
Watching social neuroscience with
@EricaFongaro
!
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Unleash the Beast !
"DIY innovation in behavioral neuroscience.
Widespread adoption of open-source tools calls for more support and training." + Mention of thebehaviourforum
Really niece piece in
@_TheTransmitter
from
@LexKravitz
and
@laubach_mark
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Colonytrack !! 🐭 "Early-life experience shapes adult social behavior in female mice." Reveals how early social interactions impact long-term hierarchy and stability in mouse communities.
#Neuroscience
#BehavioralScience
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" sample sizes can be adjusted over the course of a running experiment by conducting interim analyses in the Bayesian approach. "
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Happy to finally share my first python tool: LWTools (Livemousetracker Widget Tools), designed to help the analysis of
#LMT
data ! Simply run a "pip install LWTools". Updates and more doc to come soon!
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My work on the analyis of heart rate variability in rats with different corticosterone response to stess in finally out !
Full text available:
Thank you
@carmensandi10
and
@MATRICS_EU
Just out from the lab "Low vagal tone in two rat models of psychopathology involving high or low corticosterone stress responses" Nice collaboration with Sgoifo Lab. PhD work from
@DHuzard
Congrats!
Free copy:
@Brainmind_EPFL
@StressnetworkC
@MATRICS_EU
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It is a real honor and I am truly pleased to be awarded by
@EraNeuron
the ’Excellent Paper in Neuroscience Award’
#EPNA2022
! Thank you very much!
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Apparently, people are still wondering what TheBehaviourForum is about ?
#TheBehaviourForum
: We sit in a room and chat about how we could have done the protocol better.
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I'm delighted to announce that I'm starting a postdoc with
@ebourinet16
and
@Doctor_Amaury
: let's study the influence of social touch on behavior and heart rate variability (and use funky machines)! Thank you
@InstitutFrance
for the funding !
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Do not forget to join the behaviour forum !! We are already discussing behavioral/handling/data-analysis aspects! I am sure anyone doing behavioral research as (at least) one question ;)
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"The impact of hidden variables on neuropsychopharmacology research" : not only to read, but to think about as well !
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Working with the LiveMouseTracker is like:
#phdlife
#livemousetracker
#AcademicTwitter
#AcademicChatter
(and the scale is obviously 1:1 !)
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Review on the ecological validity of social interaction tests in rats and mice.
Interesting discussion on how to improve current laboratory models.
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Good news: "Tweeting your research paper boosts engagement but not citations" ! However, I think it is a great exercise and a nice way to discover new research, please keep doing it, at least for me ;)
#AcademicTwitter
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Woow:
• Mice seek physical contact before sleep initiation
• Somatolonging: motivation for prolonged physical contact drives huddling
• Cosleeping => coordination in neurophysiological features
• REMS timing synchronizes in males but not female or unfamiliar mice
Current Biology
Neurophysiological and behavioral synchronization in group-living and sleeping mice
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A dream conference, "recentering neuroscience on behavior " with brain-body emphasis! And what a line-up:
@jfcryan
@carmensandi10
@e_knapska
@IgorBranchi
🙏❤️
Interested in studying brain, behavior and psychopathology in a complex and integrated perspective?
Join the School:
RECENTERING NEUROSCIENCE ON BEHAVIOR: A BRAIN-BODY-ENVIRONMENT INTEGRATED APPROACH
Great speakers!
Erice, Sicily, Italy
Nov 9-14, 2024
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Très heureux de partager cet article, "Le toucher, fondement du lien social", publié dans
@cerveauetpsycho
dans lequel nous décrivons le rôle du toucher affectif sur les interactions sociales, rédigé avec
@Doctor_Amaury
biensûr :) !
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"mice engage in a form of helping behaviour towards other individuals experiencing physical pain and injury—they exhibit allolicking (social licking) behaviour specifically towards the injury site, which aids the recipients in coping with pain."
(+ ACC stuff)
Nature
Cortical regulation of helping behaviour towards others in pain
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Merci
@Epsiloon_mag
et
@Apihen
pour ce très bel article parlant du travail du labo (
@Doctor_Amaury
et
@ebourinet16
): description des effets du toucher affectif (aka 'caresses') sur la sociabilité!
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Thank you so much
@_CyrGo
and all the community for this award! And thank you again for this exciting symposium!
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Want to discuss about itch and somatosensory deficits in a 'mouse model of autism' ? Come to my
#neurofrance2023
poster on Wednesday (P1.107) !
@SocNeuro_Tweets
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Embracing change: After a challenging journey in academia, I'm excited to explore new horizons in the industry in 2024. Your support means the world to me - any leads, advice, or shares are greatly appreciated!
#CareerChange
#IndustryReady
#NewBeginnings
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Happy to share my new article! Showing that rats with constitutive differences in glucocorticoid responses had divergent Morris Water maze abilities. Free access here:
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" we discovered that face touch is a prominent form of social interaction—naked mole-rats actively engage in face-to-face contact hundreds of times in a single 10-minute social pairing. "
(+ Piezo2 stuff)
Excited to share our new pre-print where we discover behavior signatures of eusociality and social touch in the East African naked mole-rat. 1/6
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If you're interested in animal behavior, do not forget to join TheBehaviourForum! The best place to discuss and exchange about behavioral research!
#thebehaviourforum
#AcademicTwitter
#sciencetwitter
#phdchat
#scicomm
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Really happy to have been part of this great e-conference !!
@FENSorg
made science great again :) ! Thanks
@carmensandi10
!
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Voici ma première participation à un podcast de vulgarisation scientifique dans lequel je présente l'importance du toucher affectif et son pouvoir sur le corps humain et les interactions sociales. Merci à Anaïs du podcast
#neurosapiens
pour cet échange!
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I thought I'd found the perfect lab where my work ethic and innovative project align! Excited to dive in...
Oh wait! just remembered I've maxed out my 5-year postdoc term at
@Inserm
. Guess it's time to move on, Again!
#PostdocLife
#PrecariousPositions
#ScienceCareers
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Celebrating Affective Touch research with
@IASATorg
and
@ResearchINTouch
! Thank you
@LabSomato
for this exciting festival!
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Our new preprint is out ! => "Control of Social Withdrawal of Mice Deficient for the Autism Gene Magel2 by Restoration of Vasopressin-Oxytocin Dialogue in Septum"
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🧠
@lemondefr
article highlights a crucial issue in animal research: balancing scientific progress with ethics. We need smarter, more flexible oversight systems. Stopping research isn't the answer, but improving it is key! Let's innovate responsibly.
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New preprint available: Rats with different CORT responses behaved differently in the Morris water-maze. Spoiler alert: CORT improved memory retention!
(Done in
@carmensandi10
lab)
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An impressive
#opensource
monitoring system for homecage behaviors ! Looking forward to seeing more lab applications!
(
@COST_TEATIME
)
The JAX Animal Behavior System (JABS) is an
#opensource
system for studying mouse behavior. It includes methods for video annotation and classification. JABS was developed by the lab of Vivek Kumar (
@Vivekdna
). Read about it on OpenBehavior:
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"Lab mice go wild: making experiments more natural in order to decode the brain"
Interesting article. Lacking sources and solutions, but it's always good to start somewhere.
@COST_TEATIME
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Big move for preprints!
If
@CNRSbiologie
and
@Inserm
could promote preprints in their selection process, it would greatly improve the future of french science
“In a bold bid to avoid open-access fees, Gates foundation says grantees must post preprints.”
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@OdedRechavi
Don't listen to haters, french comedies are amazing
Le père Noël est une ordure (1982)
La cité de la peur (1994)
Le Dîner de cons (1998)
Astérix et Obélix, Mission Cléopâtre (2002)
RRRrrrr!!! (2004)
OSS 117 (2006 or 2009 but NOT 2021)
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AmadeusGPT ... Just wow !! This is insanely cool !! Thanks
@TrackingActions
for pushing the limits of our dreams !
🔮Ever wished you could just say what behavioral analysis you wanted? ... "Plot the animal's trajectory" "Count the head hips in the open arm"
👀🪄we present AmadeusGPT🎻 to do this ...
🗞
@shaokaiyeah
@jessy_lauer
@zhoumu53
@trackingplumes
and me
🧵⬇️
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Soon soon, the link to our new tool for all behavioral researchers will be released!! (With some focus on homecage monitoring solutions!)
Need help with using
#homecage
systems for
#mouse
or
#rat
#behavior
monitoring?
Looking for the best way to analyze the data?
Don't have a protocol that fits your research question?
We have a solution for you! Stay tuned...
@The_EARA
@FENSorg
@EBBS_Science
@COSTprogramme
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Just hoping I can put a fur on my mice for the cover of my next article on ASD preclinical research!
#AcademicTwitter
#AcademicTwitter
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2023 starts well for 'social touch': "Touch neurons underlying dopaminergic pleasurable touch and sexual receptivity".
In addition to C-LTMRs driving social touch, Mrgprb4-lineage neurons are important for sexual-social behaviors.
Looking forward to the next discoveries !
Excited to share my lab’s new paper out today
@CellCellPress
.
"Touch neurons underlying dopaminergic pleasurable touch and sexual receptivity"
Congratulations to this amazing team of scientists.
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"Massage-like stroking alleviates noxious heat pain and incision-induced mechanical hypersensitivity"
No mention of C-LTMRs or other previous findings on the decrease of pain linked to affective touch... Isn't it weird?
Good way to start 2024, new publication in
#neurobiolpain
,
@zachary_waarala
showed that massage induces analgesia in mice and it isn't block by opioid antagonist. One of our most unexcepted finding!
BTW
#NeurobiolPain
super quick!
@msupsl
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My opinion: "size doesn't matter" !
Really
The human does !
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Testing LabGym on some of my mice videos, it looks pretty cool so far!
#labgymbeh
from
@byneuron
lab.
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@TroncheBiais
@Univ_Lorraine
Triste réalité !
(j'ai récemment vu un radiothérapeute prescrire du Passiflora pour un 'aider' un patient de radiothérapie pour un cancer incurable ... triste réalité ...)
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Ready for 'circuit mechanisms in maladaptive emotional response' and great line-up : Anna Athanassi ,
@anna_beyeler
,
@sebneuro
@BiancaASilva11
and Frank Meyer ! 🙏
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Great and inspiring talk from
@NobelPrize
laureate
@ardemp
: a journey with the Piezo mechanoreceptor !
@NeuroSchool_mrs
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And now Emotions ?! Cool !! Wanna try it !!
" SEB3R, an automated method for tracking mouse body language and studying emotional behaviors "
SEB3R is an automated method for studying emotional behavior using pose data. It allows for tracking emotional expression over time. Read about SEB3R in this week's post on OpenBehavior.
#opensource
#AI
#neuroscience
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Thanks
@EraNeuron
for the interview ! (p17 to read my not-so-optimistic vision of science carreer as a postdoc in France
@Inserm
;) )
Excited to share our latest issue of the NEWSLETTER - No 42!
Featuring the results of NWGC2022 on Chronic Pain, overview of the midterm symposium that took place in Madrid in January, an interview with the EPNA2022 awardee and more!
Read all about it here:
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Groundbreaking: ELKIN1, an ion channel, plays a vital role in light touch sensation in mice! Its absence leads to diminished touch sensitivity. Great new insights from
@GaryRLewin1
's lab on the mechanics of touch perception.
#Neuroscience
#TouchSensation
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"We find that ADHD symptomatology and touch sensitivity are directly linked, using both self-reports and experimental measures. We also find evidence of tactile sensory overload in ADHD, and an indication that this is linked to inattention specifically."
Interesting in somatosensation and (adult) ADHD?
Have a look at our preprint:
We find altered neural processing to tactile stimuli and a link to subjective tactile sensitivity and inattention.
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Paper accepted!! Let's celebrate with a new experiment !! Saying 'Hi again' to my
#skinnerve
friend !
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I hope key players in behavioral neuroscience will join:
@carmensandi10
,
@BohacekLab
,
@TrackingActions
,
@anna_beyeler
,
@IshmailSaboor
,
@leafs_s
,
@DulacLab
,
@camillabellone
,
@jfcryan
,
@MartinGiurfa
,
@GraeffJohannes
,
@Vivekdna
,
@kaymtye
,
@mumumouse
,
@MathiasVSchmidt
..
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Turning science into 'art' 🎨 Holiday activity: repurposing my old scientific poster for a family painting session. Do you also paint on the B-side of your posters ??
#ScienceMeetsArt
#SustainableScience
#AcademicTwitter
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So proud to be part of this amazing journey with
@Doctor_Amaury
!! (And happy to see our cute skin-nerve electrophy setup :-p )
💫Amaury François (
@Doctor_Amaury
) est lauréat Impulscience 2022 ! Pour en savoir plus :
#recherchescientifique
#chercheurs
#sciences
#lifescience
#talentfondationbettencourt
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Really interesting findings on not-so-social adult mice:
"Mice have no preference when sated, and prefer food over social when food-deprived" and "Mice prefer food over a familiar social stimulus."
Excited to share that my latest paper with
@veenemalab
was accepted! 🥳
Interested in social interaction-seeking, food-seeking, SABV, age differences, and/or rodent model comparisons?
You can access the article for free for the next 50 days:
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Do not miss The Social Brain workshop ! amazing line-up !!
Save the data for for this exciting workshop on social interactions organized by
@carmensandi10
@camillabellone
and myself in Andalusia next Fall. DM me for more information.
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Don't miss those postdocs opportunities with
@Doctor_Amaury
!! Affective touch, social interactions, really cool technics and much more !!
Post-doc positions available!
Interested in affective touch and its central representation? Come join us in the beautiful city of Montpellier, we are seeking a postdoc experienced with in-vivo electrophysiology or in-vivo imaging.
Apply through the CNRS link or PM me
Please RT
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Overall, we demonstrate that there is a neuronal population, innervating the skin, dedicated mainly to the detection of social/affective touch and we show that the activation of this neuronal pathway is intrinsically pleasant. (6/11)
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" The 3Hs initiative focuses on housing, handling and habituation of laboratory rodents and methods which increase their positive affective experiences and reduce cumulative suffering."
+ webinar on march 27th
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*Piezi-Piezo papapalala !*
" The neurons can basically feel the pulse within the brain. There is a direct way within the brain to know about the heartbeat "
@_TheTransmitter
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Amazing talk, behavioral analysis, science and homecage technology development by
@eburguiere
!
The BEATBOX solution will be a game changer!!
@COST_TEATIME
#homecagemonitoring
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I recently joined the
@COST_TEATIME
action, aiming at improving automated laboratory homecage monitoring systems... And we are soon launching something highly needed to all 'behaviorists' ;) ! Stay tuned!
We are preparing something delicious this summer!
More info will be provided soon, so stay tuned!
#homecage
#knowledgetransfer
#behavior
#monitoring
#DataAnalysis
#mouse
#rat
#research
#experiment
@COSTprogramme
#COSTAction
#TEATIME
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Highly recommended 'summer school' on Homecage monitoring systems!!
#teatime
@COST_TEATIME
Are you working on home cage monitoring? Attend the
@COST_TEATIME
summer school! Exciting opportunity.
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" Time perception is thus as deeply intermeshed within the sensory processing pathway as is the sense of touch itself, suggesting that the experience of time may be further investigated with the toolbox of sensory coding. "
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@kmaccio
@Benoit__Girard
@camillabellone
Looks really nice ! (I suggest a presentation post on TheBehaviourForum ;) )
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More coolness with keypoint-Moseq :) (
@MoSeq4All
)
Such fun to finally see those amazing tools applied to my friends!
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Exciting findings reveal MDMA's potential as an empathogen! 🧠🐭 Study shows MDMA enhances empathy-related behaviors in mice (Shank3), shedding light on its mechanism via 5HTsignaling in the NAc.
#MDMA
#EmpathyResearch
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"Neuroscience needs a research-video archive" (by
@Froemkelab
in
@_TheTransmitter
)
Happy to see others raising a hard issue nowadays:
"Video data are enormously useful and growing rapidly, but the field lacks a searchable, shareable way to store them."
What platform/website/repository could be used to openly share a scientific video protocol ?
#OpenScience
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Finally, we studied naturally-occurring social dynamics after C-LTMR activation, in the Live-Mouse-Tracker (LMT): C-LTMR potentiation increased social contacts (e.g. nose-to-nose explorations) and we observed a diminution of isolated behaviors (in blue). (5/11)
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Pushing the limits with iMRSIV VR for mice!
Excited to share iMRSIV, immersive VR goggles for mice:
This work was enabled by the great team assembled, as it required both creativity and technical prowess: Dom Pinke, Greg Dobos, Gabe Dara,
@DanielDombeck
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Sad to see that scientists still have to neglect personal life and students to be able to "succeed" ...
Got invited for
@ERC_Research
Consolidator Grant interview in October. The three months of intensive grant writing (while negleting my personal life and my students) paid off 🤩🤩🤩
@i2sysbio
@UV_EG
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Insane!! "Through advanced analytics approaches applied to mechano-acoustic signals of diverse body processes, the device yields heart rate, respiratory rate, physical activity, temperature, and behavioral states."
It takes a village... and about 5 years.. to raise some papers. This collaboration was led by Dr. Wei Ouyang (just opened his lab at Dartmouth!) from the
@ProfJohnARogers
group, in collaboration with
@treemi
lab and our industry partner
@NeuroLuxInc
.
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"We identify key stages of preoptic development, including the perinatal emergence of sex differences, postnatal maturation and subsequent refinement of signaling networks, and nonlinear transcriptional changes accelerating at the time of weaning and puberty."
I am thrilled to share new work from the lab led by
@harris_kaplan
investigating the emergence of hypothalamic cell types involved in social behavior and homeostatic control. 1/9
Sensory Input, Sex, and Function Shape Hypothalamic Cell Type Development
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Really elegant study from
@carmensandi10
's lab on the link between mitochondrial function of NAc D2 neurons and social dominance (in rats and mice).
Just out from the lab! New read!
We show that mitochondrial mitofusin 2 in nucleus accumbens D2, but not D1, medium spiny neurons regulates social dominance & mito & neuronal phenotypes!
Congrats to
@SriparnaGhosal
S_Astori &all the team!
@Brainmind_EPFL
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The lab is still looking for a postdoc to study the central representation of affective touch and its effects on behavior!! IN VIVO EPHYS EXPERT WANTED !! please share ! And contact
@Doctor_Amaury
for more info ;)
#AcademicChatter
#postdocjobs
Post-doc positions available!
Interested in affective touch and its central representation? Come join us in the beautiful city of Montpellier, we are seeking a postdoc experienced with in-vivo electrophysiology or in-vivo imaging.
Apply through the CNRS link or PM me
Please RT
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Congrats
@EricaFongaro
for showing the great capacity of crows in using attention to control working memory. Freshly published in
@SciReports
!
Enjoy and share the skills of crows described in my new paper! 😍
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Be careful, this method to freely access 'all research articles' is forbidden in France, it might be too in other countries ;) !
Rappel pour nos amis chercheurs et étudiants : il est INTERDIT d'utiliser ce site qui permet d'accéder à tous les articles de recherche gratuitement !
Ce site est souvent bloqué par les fournisseurs internet, il est aussi interdit de contourner le blocage avec cette méthode. 🧵
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@TrackingActions
I hope: guidelines on 'how not to over-interpret observed behavior' :-p ! (Probably not but Highly needed!).
We also have a cool thing for all behaviorists coming soon with
@COST_TEATIME
;)
@BohacekLab
@anna_beyeler
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After exciting discussions about the Live Mouse Tracker at
@FENSorg
, back to the workshop ! Let's upgrade it with homemade 3d-printed food dispensers. (Model available!) (
@fabdechaumont
)
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Current mouse behavioral tests of anxiety are not reliable... "In view of scientifically valid and ethically responsible research, we call for a revision of behavioural tests of anxiety in mice and the development of more predictive tests."
Reliability of Common Mouse Behavioural Tests of Anxiety: a Systematic...
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We validated that activating the C-LTMR cells (with CNO injection) was “rewarding” to the animals since the showed a preference for the side in which their C-LTMRs were activated. (4/11)
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Covid vaccine shots booked ✔️. Looking forward to becoming an mARN chatbot 🧬📬
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