Colt Egelston
@ColtEgelston
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Immuno-Oncology at City of Hope. Lover of beagles and a long run.
Los Angeles, CA
Joined April 2009
Our paper on the role of exhausted CD8+ T cells in breast cancer patients is out!
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RT @CIR_AACR: Organ-Specific Immune Setpoints Underlie Divergent Immune Profiles across Metastatic Sites in Breast Cancer. .
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RT @HMcGeeMDPhD: I am excited to share a discovery from a large international collaboration led by @cityofhope published on PubMed this we….
medrxiv.org
The incidence of colorectal cancer (CRC) among individuals under age 50, or early-onset CRC (EOCRC), has been rising over the past few decades for unclear reasons, and the etiology of the disease...
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RT @SaulPriceman: Proud of our work published today in @NatureMedicine, sharing results from our phase 1 trial with PSCA-CAR T cell therapy….
nature.com
Nature Medicine - A phase 1 trial of PSCA-targeting CAR T cell therapy in patients with PSCA-positive, metastatic castration-resistant prostate cancer demonstrates that the treatment, using a...
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RT @AkoyaBio: 🔆 Are you ready, San Diego? The #IlluminationTour will be coming your way on Wednesday! Hear about the latest advances from A….
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RT @AkoyaBio: 🌏 We're going west for the next stop on the #IlluminationTour2024: SAN DIEGO. Join us at Green Acres Campus Point on May 22….
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RT @AkoyaBio: Hear from @CureCancerAu's 2023 Researcher of the Year, @Aruthak, about how #singlecell #spatialphenotyping is an invaluable t….
akoyabio.com
Dr. Arutha Kulasinghe discusses how to characterize the tumor microenvironment and develop consistently predictive biomarkers for guiding patient selection for highly targeted therapy
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RT @mgfakih: Immunotherapy Response in Microsatellite Stable Metastatic Colorectal Cancer Is Influenced by Site of Metastases - European Jo….
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RT @Nature: ChatGPT use shows that the grant-application system is broken
nature.com
Nature - The fact that artificial intelligence can do much of the work makes a mockery of the process. It’s time to make it easier for scientists to ask for research funding.
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Great article and best cover ever.
New issue online! Cover depicts work from Esterházy, Brown, @macyrkomnick &co identifying lymph node co-drainage between pancreas, gut, & liver that leads to immune crosstalk & impacts pancreatic autoimmunity. Image by Hailey Brown, inspired by the #Chicago metro rail map
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RT @worldscientific: Welcoming #WSARCI to the @WorldScientific Annual Review portfolio! Publishing research across the field of immuno-onco….
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RT @SaraMcArdle1: 📢*Announcing 2 Image Analysis Training Courses!*. 1) @QuPath Training Course- October 9-11, San Diego, CA..
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RT @drsarahsam: Thank you #ShannenDoherty for sharing your experience with breast cancer brain metastases, a common occurrence in #MBC. Awa….
people.com
Shannen Doherty, who was diagnosed with stage 4 breast cancer, wrote on Instagram: “The turmoil….. the timing of it all…. This is what cancer can look like."
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RT @PTarantinoMD: Elacestrant, alpelisib, capivasertib, everolimus, ribo maintenance. A rapidly expanding arsenal to fill the critical gap….
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RT @mgfakih: Proud to lead this work. RIN study was a single center trial at City of Hope. More evidence that IO combinations can be of gre….
jamanetwork.com
This nonrandomized clinical trial assesses the recommended phase 2 dose of regorafenib, ipilimumab, and nivolumab immunotherapy for patients with refractory microsatellite stable metastatic colorec...
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RT @carmonation: Love Singlecell?. Learn together with Jean Fan @JEFworks, Ido Amit @IdoAmitLab, Dominic Grün @dominic_grun, Fabian Theis @….
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Wow tissue localization of individual TCRs. This will really expand our understanding of the R cell dynamics in the TME!.
Presenting Slide-TCR-seq: our method for measuring the transcriptomes of cells & T cell receptor (TCR) sequences in situ!. This collaboration w/ Bryan Iorgulescu, Shuqiang Li, Catherine Wu, and @insitubiology led to some cool findings. 1/8
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RT @LAelectionbot: Election Update- Tue Jun 14 2022 23:11:01.LOS ANGELES CITY PRIMARY NOMINATING ELECTION Member of the City Council, 1st D….
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One of many reasons I'm voting for @EunissesH for CD1: support of better bike infrastructure, which the incumbent has failed to do! Succinctly put by the @latimes #LosAngeles
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