Cancer Immunology Research
@CIR_AACR
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Follow Cancer Immunology Research for outstanding research across the cancer immunology discipline, accelerating effective immunotherapies. Published by @AACR.
Joined July 2018
What We're Reading: Article Recommendations from Our Deputy and Senior Editors
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In Situ Delivery of Gasdermin E mRNA Promotes Antitumor Immunity via Creatine-Elicited Type I Interferon Signaling in Monocytes:
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Cytotoxic Chemotherapy in a 3D Microfluidic Device Induces Dendritic Cell Recruitment and Trogocytosis of Cancer Cells:
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Cytoplasmic WEE1 Promotes Resistance to PD-1 Blockade Through Hyperactivation of the HSP90A/TCL1/AKT Signaling Axis in NANOGhigh Tumors:
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Naturally Arising Memory-Phenotype CD4+ T Lymphocytes Give Rise to Multiple Helper Subsets to Contribute to Tumor Immunity while Inhibiting GVHD:
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Memory-like Natural Killer Cell and CD19 Antibody–Based Immunotherapy in Combination with Tyrosine Kinase Inhibition Has Antitumor Effects against Ph(-like) Acute Lymphoblastic Leukemia:
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CAR Binders Affect CAR T-cell Tonic Signaling, Durability, and Sensitivity to Target:
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IL-15 Complex Enhances Agonistic Anti-CD40 + Anti-PDL1 by Correcting the T-bet to Tox Ratio in CD8+ T cells Infiltrating Pancreatic Ductal Adenocarcinoma:
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Sign up to receive alerts directly to your inbox to keep up with the latest published issues:
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Anti-CTLA4 Therapy Leads to Early Expansion of a Peripheral Th17 Population and Induction of Th1 Cytokines:
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Eph Receptors Activate Myeloid Checkpoint Receptor LILRB5 to Support Tumor Development:
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Congratulations to Veronika Lutz, PhD, Christian Bauer, MD, and colleagues, recipients of the 2025 Cancer Immunology Research Award for Outstanding Journal Article. Learn more and read the article:
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Mesenchymal Stem Cells and Fibroblasts Contribute to Microvascular Proliferation in Glioblastoma and are Correlated with Immunosuppression and Poor Outcome:
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What We're Reading: Article Recommendations from Our Deputy and Senior Editors
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Read the latest Editors' Pick: Selective STING Activation in Intratumoral Myeloid Cells via CCR2-Directed Antibody–Drug Conjugate TAK-500
Editors’ Picks from the AACR journals highlight how tumor mutations mirror high-altitude oxygen adaptations, immune-based therapies, and environmental cancer risks, among other topics. Learn more on the #AACRBlog:
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PTP Inhibition Improves the Macrophage Antitumor Immune Response and the Efficacy of Chemo- and Radiotherapy:
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Antitumor CD4+ T Helper 1 Cells Target and Control the Outgrowth of Disseminated Cancer Cells:
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