Christian Dzuvor
@CDzuvor
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Postdoc @KizzyPhD_Lab @HarvardChanSPH|Interested in Novel Vaccine Development and Antibody Therapeutics against Coronaviruses and Emerging Infectious Diseases
Boston, MA
Joined January 2019
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 It started from my frustration with the depressing effect that the current publishing system has
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BREAKING: COVlD surges across the U.S. 20 states & D.C. are in High or Very High transmission. Only 1 state is Very Low. PMC estimates the U.S. will top 1 million new daily infections tomorrow. Full report on Monday.
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It’s time for another Precision vaccine conference. Join the conversation
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Trump on Florida eliminating vaccine requirements: "It's a tough stance. You have vaccines that work. They just pure and simple work. They're not controversial at all and I think those vaccines should be used. Otherwise some people are going to catch it and they endanger other
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I agree.
Trump on Florida eliminating vaccine requirements: "It's a tough stance. You have vaccines that work. They just pure and simple work. They're not controversial at all and I think those vaccines should be used. Otherwise some people are going to catch it and they endanger other
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Excited to share our new @NatureMicrobiol paper revealing the most complete arenavirus glycoprotein complex (GPC) structures to date 🤩@TheColinMann @HarvardMicro @VirologyHarvard
nature.com
Nature Microbiology - Cryo-EM structures of the full-length Junin virus and Machupo virus spike glycoprotein complexes stabilized in the prefusion conformation. Analyses reveal features that...
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🚨 New paper alert! 🚨 Here we show that stabilized influenza hemagglutinin HPAI H5 immunogens improve the quality of elicited antibody responses. Thank you to @open_phil for funding this work!
biorxiv.org
Transmission of highly pathogenic avian influenza from H5 clade 2.3.4.4b has expanded in recent years to infect large populations of birds and mammals, heightening the risk of a human pandemic....
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We’re looking for early stage investigators (Sr. Postdocs, Instructors, Asst Profs, etc) to join our ReVAMPP Center designing vaccines and antibodies against paramyxoviruses and bunyaviruses! Read more and apply here:
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Excited to share our paper identifying that bat coronavirus HKU5 uses ACE2 from its native bat host and American mink as a receptor. This highlights farmed mink has a high risk intermediate host for HKU5-like viruses. https://t.co/kyb1eaLeaO
@YaleIBIO @YaleMed
nature.com
Nature Communications - Alfajaro et al identify that a bat MERS-like coronavirus HKU5 uses ACE2 as a receptor from its natural bat reservoir Pipistrellus abramus and American mink. Structural...
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Microfluidics combined with electron microscopy for rapid and high-throughput mapping of antibody–viral glycoprotein complexes https://t.co/y82IPcqCFz
nature.com
Nature Biomedical Engineering - A microfluidics- and electron-microscopy-based method enables the characterization of polyclonal antibody responses to infection and vaccination.
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In situ insights into antibody-mediated neutralization of a pre-fusion Junin virus glycoprotein complex: Cell Reports https://t.co/yWMiVUad31
cell.com
Taylor et al. use single-particle cryo-EM to determine the in situ structure of a Junin virus glycoprotein complex (GPC). Structures of GPC-bound neutralizing antibodies, CR1-28 and J199, uncover...
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🎉 Huge congratulations to Dr. Jason McLellan for winning the Changemakers Award! 🏆 His groundbreaking work in the fight against infectious diseases, including his contributions to the COVID-19 vaccine, is nothing short of inspiring. Well-deserved recognition! 🙌👏 #Changemaker
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Thrilled to share our new paper in @NatureSMB ! We report DS90, a potent #nanobody against #Nipah and #Hendra virus - the product of an incredible national & international collaboration across 🇦🇺🇨🇱🇨🇳🇬🇧. https://t.co/b2BmzNqpkK
@UQ_SCMB (Free access preprint provided below 👇)
nature.com
Nature Structural & Molecular Biology - Here, Isaacs, Nieto and Zhang et al. discover a potent nanobody and engineer a dual-action antibody that targets two viral proteins, offering strong...
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#ICYMI Congratulations to Institute Scholar Christopher Barnes @cobarnes27 for being named a Freeman Hrabowski Scholar! The Barnes lab is working on next generation vaccines and antibody-based treatments to tackle emerging RNA viruses. https://t.co/aZDF6U7H3H
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Latest preprint from the lab, many years in the making! By combining #cryoEM with #AlphaFold3 modelling, we propose that NS3 forms a transmembrane RNA translocase. This could have big implications for our understanding of norovirus replication (🧵) 🔗 https://t.co/vNbcLqaZof
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A new review is out on currently licensed mucosal COVID-19 vaccines. Great work by Alina Tscherne from my team at @MedUni_Wien Available (open access) here: https://t.co/d8p1Nn347k
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Think coronavirus spikes have run out of surprises? Think again. Our latest preprint dives into the highly unusual spikes of marine mammal coronaviruses. https://t.co/DE0rFm2W4g This #cryoEM study was led by @rubenhulswit, with key contributions from an amazing team.
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Sooo happy to finally have this one published!! (3 years in the making… 👀) A comprehensive investigation into the recency and geographical origins of both SARS-CoVs that spilled to humans in the past few decades, now in @CellCellPress
cell.com
Recombination-aware evolutionary analyses of the entire genomes of SARS-CoV-1-like and SARS-CoV-2-like viruses indicate that SARS-CoV-1 and SARS-CoV-2 descend from bat coronaviruses that circulated...
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Just out @Nature Nasal vaccines for respiratory infections Best review I've seen on this important topic and a big unmet need https://t.co/EVgmh2o6ho
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FDA-approved vaccines had randomized, placebo-controlled trials. Polio? Measles, mumps, rubella? Haemophilus influenzae B? Diphtheria, tetanus, pertussis? Meningococcus? Varicella? Pneumococcus? Rotavirus? RSV? Hep B? Influenza? HPV? COVID-19? Shingles? YEP. A thread🧵 1/
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