Colin Mann
@TheColinMann
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🌲St.Paul🌲✈️ 🌴 San Diego🌴 ✈️ 🏛️Boston🏛️ Harvard Virology PhD Candidate - Abraham Lab - Structural Virology & Antibodies
Boston, MA
Joined September 2018
So glad to finally present our work on JUNV and MACV GPC in @NatureMicrobiol! Thankful for the contributions of all our co-authors, including collaborators @florian_krammer and Yuemin Bian. And special thanks to @HC2EM for their help with the Cryo-EM!.
Excited to share our new @NatureMicrobiol paper revealing the most complete arenavirus glycoprotein complex (GPC) structures to date 🤩@TheColinMann @HarvardMicro @VirologyHarvard
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RT @dr_demetre: My resignation letter from CDC. Dear Dr. Houry,. I am writing to formally resign from my position as Director of the Nat….
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RT @NatureMicrobiol: Out Now! Molecular organization of the New World arenavirus spike glycoprotein complex #Arenav….
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RT @structurabio: When particles have orientation bias, the resulting maps are often streaked along the missing directions. In this case st….
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RT @DrNeilStone: RFK Jr's pick for Surgeon General sells wearable monitors . MAHA is one big sales scam
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RT @noelTbrewer: The 17 fired members of ACIP, including me, have written an article in JAMA about our experience and our concerns. https….
jamanetwork.com
In this Viewpoint, former members of the Advisory Committee on Immunization Practices (ACIP) caution that the sudden change in the ACIP may reverse the achievements of US immunization policy,...
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RT @abrahamlabhms: TWiV podcast discussing our recent @CellCellPress paper on shifts in receptor use by an encephalitic arbovirus! Congrats….
microbe.tv
TWiV reviews pause in the use of Chikungunya vaccine, HHS to stop recommending COVID shots for pregnant women and children, molecular basis for shifted receptor recognition by encephalitic alphavir...
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RT @abrahamlabhms: Excited to share a preview on "Decoding WEEV’s host adaptation" in @cellhostmicrobe featuring papers from @abrahamlabhms….
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RT @joostsnijder: Simultaneous polyclonal antibody sequencing and epitope mapping by cryoEM and mass spec: how far can we go? Check out the….
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RT @abrahamlabhms: Our study on the molecular basis of shifts in receptor recognition by western equine encephalitis virus (WEEV) in the pa….
cell.com
Cryo-EM structures and mutational analyses reveal western equine encephalitis virus E2-E1 glycoprotein polymorphisms that determine shifted receptor usage and allow for sequence-based prediction of...
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RT @VirusesImmunity: NIH indirect costs fund the backbone of research: maintaining labs, ensuring safety, and supporting admin work. These….
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Interested in displaying diverse antigens on the outside of virosomes? Check out this awesome protocol from @viccwhat and @virologylindsey from the @lingwoodlab!.
star-protocols.cell.com
STAR Protocols is an open access, peer-reviewed journal from Cell Press. We offer structured, transparent, accessible, and repeatable step-by-step experimental and computational protocols from all...
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RT @abrahamlabhms: Absolutely thrilled to share paper on Nipah polymerase in close collaboration with Rachel Fearns at Boston University @B….
cell.com
The cryo-EM structure and mutational analysis of the Nipah virus polymerase complex identify features critical for RNA replication and transcription with the potential to aid in the development of...
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RT @abrahamlabhms: Thank you to everyone who contributed, including @wanyuviridae, @xiaoyi_fann, @jessica_oros_, @jplung2, @himanishbasu, @….
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RT @ReikaWatanabe2: cryoTIGER: Deep-Learning Based Tilt Interpolation Generator for Enhanced Reconstruction in Cryo Electron Tomography htt….
biorxiv.org
Cryo-electron tomography enables the visualization of macromolecular complexes within native cellular environments, but is limited by incomplete angular sampling and the maximal electron dose that...
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The crazy part is, if we found the mRNA vaccines to STILL be expressing spike years later that would be a huge win for the platform. A lot of research has gone into achieving durable expression to prolong humoral development. Years-long in vivo stability would be surprising tho.
Are you sure that this is even close to right? I get it feeds the anti vax folks you value but I am told by people who are doing this research at the highest levels that it is wayyyyy off.
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I love being in science. Cafe employee I know well said she had pain and wanted some ibuprofen. I offered to run up to the lab and get some. But as I turned to leave another guy whips out a 50mL conical tube full of em and offers her some! I need to use lab ware more effectively.
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Confirmation that biology is the best!.
Nobel Prize in Physiology or Medicine: Biology.Nobel Prize in Chemistry: Biology.Nobel Prize in Physics: Sounds like Biology. #NobelPrize.
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