Craig Wilen
@WilenLab
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Physician-scientist. Dad. Husband. Associate Professor @yaleibio @yale_labmed. We study host-viral interactions #covid #norovirus @wilenlab.bsky.social
New Haven, CT
Joined May 2011
RT @NatureMicrobiol: Out Now! Amino acid changes in two viral proteins drive attenuation of the yellow fever 17D vaccine .
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RT @BogunovicLab: Latest from us. Universal antiviral made! How? Transient gene therapy. Which genes? Only 10 suffice, out of thousands of….
science.org
A human inborn error of immunity guided discovery and development of a prophylactic, mRNA-based antiviral.
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RT @RathinamVA: Why does RNA undergo glycosylation? Excited to have our new paper out. We in collab w/ Ryan Flynn show N-glycans on glycoRN….
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RT @VinnieViruses: Hi everybody! I am super excited to share the work done during my PhD published in @nature today! We describe a new mech….
nature.com
Nature - N-glycans on glycoRNAs prevent innate immune sensing of endogenous small RNAs, and the natural mechanism they use demonstrates how glycoRNAs exist on the cell surface and in the endosomal...
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RT @AdrianoAguzzi: My whole lab thinks that the last paragraph of a paper's Introduction should report the Results of the study. I don't pu….
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RT @DrCatharineY: ICYMI: Finally some good news! The senate committee rejected the 40% budget cut for NIH and instead endorsed a $400 mill….
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RT @Lo_Zanzi: #WeekendRead! #EveryCellIsAnImmuneCell! Kaelberer Bohorquez &co show @Nature that via #TLR5 flagellin drives neuropeptide PYY….
nature.com
Nature - A study reveals a gut–brain sensory pathway through which the microbial component flagellin activates neuropod cells in the colon to signal the brain and reduce feeding in mice.
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This was a great collaborative effort between many groups particularly the @NIH VRC and led by co-first authors @MiaAlfajaro, Em Keeler, Ning Li and Danny Douek, Yaroslav Tsybovsky, Leonid Serebryannyy, and Tongqing Zhou.
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Excited to share our paper identifying that bat coronavirus HKU5 uses ACE2 from its native bat host and American mink as a receptor. This highlights farmed mink has a high risk intermediate host for HKU5-like viruses. @YaleIBIO @YaleMed.
nature.com
Nature Communications - Alfajaro et al identify that a bat MERS-like coronavirus HKU5 uses ACE2 as a receptor from its natural bat reservoir Pipistrellus abramus and American mink. Structural...
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RT @Goodman_lab: New paper! Combining epidemiology and experiments uncovers surprising drug-host-microbiome-pathogen interactions. Congrats….
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RT @ScienceMagazine: By flipping an evolutionarily disabled genetic switch involved in Vitamin A metabolism, researchers in Science have en….
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RT @SciImmunology: The July issue of Science #Immunology is out!. This month's cover features a study that demonstrates how the transcripti….
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RT @JosephBurclaff: A new paper discussing the importance of federal, institutional, and programmatic support for physician scientist train….
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RT @MucosalImmunol: Memory T cell formation and phenotype varies across intestinal compartments: .
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RT @AJamesMcCarthy: On Sunday I traveled to the middle of the desert to capture this: The ISS against our sun. What I didn't expect: the su….
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RT @Elinav_Lab: On leadership & support- meet the amazing first responder team (partial) who voluntarily worked during first 12h, in darkne….
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