
Vagheesh Narasimhan
@vagheesh
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Leading a group focused on AI + Genomics. Assistant Professor in the Departments of Integrative Biology | Statistics and Data Science @UTAustin
Austin, TX
Joined May 2010
Humans are the only bipedal great apes, due to the evolution of our unique skeletal form. What genomic regions underlie such change? Our cover article in @sciencemagazine led by @EucharistKun and in collab. with @tarjs is now out!
By combining data from full-body x-ray images and associated genomic data from more than 30,000 UK Biobank participants, researchers have provided new insights into the evolution of the human skeletal form. Learn more this week in Science:
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RT @IncNaturalist: Safety first, always hold on to the handrail! Except for when there is a massive Sunda King Cobra lying along the top of….
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RT @StevenSalzberg1: Uh oh: deep learning models in genomics lose badly to very simple linear models. Could they have been over-hyped? (new….
nature.com
Nature Methods - The analysis presented in this Brief Communication shows that, despite their complexity, current deep learning models do not outperform linear baselines in predicting gene...
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Huge congratulations to Adam Klivans, for renewing the NSF Institute for the Foundations of Machine Learning at UT Austin with intent to expand generative AI to protein engineering and clinical imaging.
nsf.gov
The investment will accelerate open innovation, empower an AI-ready workforce and strengthen U.S. global competitiveness...
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Listening to RD talk about early days of genome sequencing is still amazing! .
thenakedscientists.com
Helix research, at the double...
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Our new paper on ancient DNA to address the spread of Uralic languages now out in @nature (we started working on this in 2018). Many interesting results, including a sample from ~16k years ago Yakutia that can be modeled as an unadmixed Native American.
nature.com
Nature - Genome-wide sequencing of 180 ancient individuals shows a continuous gradient of ancestry in Early-to-Mid-Holocene hunter-gatherers from the Baltic to the Transbaikal region and distinct...
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Incredible! Dragon man is a Denisovan. Major congratulations Qiaomei Fu.
cell.com
A mitochondrial genome from Middle Pleistocene hominin dental calculus from northeastern China clusters with mtDNAs of early Denisovan individuals in Siberia, linking a nearly complete cranium to...
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RT @FridoWelker: Incredibly proud that our paper on the #palaeoproteomics analysis of the Penghu mandible, led by @tsutatsuta.bsky.social a….
science.org
Denisovans are an extinct hominin group defined by ancient genomes of Middle to Late Pleistocene fossils from southern Siberia. Although genomic evidence suggests their widespread distribution...
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RT @xliaoyi: Thrilled to share that the first project from my PhD is now published in Science (@ScienceMagazine)! 🎉. We studied the genetic….
science.org
Human pelvic evolution following the human-chimpanzee divergence is thought to result in an obstetrical dilemma, a mismatch between large infant brains and narrowed female birth canals, but empirical...
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RT @millanek1: Want a to make genetic maps from sperm/pollen/gametes? Now there is an easy way, based on Hi-C sequencing. Thanks to Richar….
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RT @brainevodevo: Pleasure to co-edit this issue of Current Opinion on human genetic origins with @jsteinlab with support from @ELS_Genetic….
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RT @MarkTransposon: How did humans develop unique traits despite sharing nearly identical genomes with other primates like chimpanzees? Tog….
nature.com
Nature - The cis-regulatory functions of human accelerated regions of genomic loci and their potential contribution to human brain evolution are revealed.
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Whenever I'm feeling a little out of it scientifically or think I need huge sample sizes to say anything meaningful, I often re-read Green et al, Science, 2010. It's a truly otherworldly paper and of course duly won the Nobel Prize. The supplement is just🔥
science.org
Gene flow has occurred from Neandertals to humans of Eurasian descent, but not to Africans.
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The duality principle in biology: A single human zygote contains all the information you need to develop into an adult human and at the same time contains within it, the evolutionary history of our species.
Interesting article from @WiringTheBrain that develops variational auto encoders (VAEs) as a metaphor for the relationship between genome and organism, with the genome corresponding to the compressed representation. I like the 'generative model' metaphor better than the
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Growing up I was never a human evolution guy. I liked reptiles! But a @NatGeo article changed my view on things and I became obsessed. This is an amazing article that’s equally exciting
nationalgeographic.com
Stunning discoveries and fresh breakthroughs in DNA analysis are changing our understanding of our own evolution and offering a new picture of the Neanderthals and Denisovans that our ancestors met...
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RT @Dr_RajeshGopal: New paper in @ScienceMagazine shows tiger distribution in India increased by 30% in the last two decades. It now suppor….
science.org
Recovery of large yet ecologically important carnivores poses a formidable global challenge. Tiger (Panthera tigris) recovery in India, the world’s most populated region, offers a distinct opportun...
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RT @ScienceMagazine: This tigress has reclaimed the ancient fort within Bandhavgarh Tiger Reserve and made it her home. Protection, prey,….
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RT @NoonanLab: Out today in Cell: a comprehensive map of Human Accelerated Region gene targets in human and chimpanzee neural stem cells. T….
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