New study finds that advanced Alzheimer’s disease (AD) can be reversed by restoring brain NAD+ homeostasis (in mice)! Also found the severity of AD correlates with NAD+ homeostasis dysregulation, & preserving brain NAD+ homeostasis prevents AD in mice: https://t.co/zKKFLP1T2S

Sorry to ask instead of searching, but is the US Pro 2000 preferred over the 1000? I know the differences in power and duty cycles, but don’t know which is more versatile in use (for vagal nerve stimulation & MECFS). Doesn’t cranial US necessitate the 2000?

Thanks! Someone was just asking me if B12 patches existed.

People with MECFS scrambling to read the BF protocol rn:

Boston Children’s Hospital followed over 1,000 COVID-19 patients and found that those with a common MTHFR gene variant and early disruption in methionine metabolism were more likely to develop severe or long COVID. https://t.co/qDUvQk0AIV

“Parkinson’s rates in the US have doubled in the past 30 years. And studies suggest they will climb another 15 to 35 percent in each coming decade. This is not how an inherited genetic disease is supposed to behave.” Because it’s mostly environmental. https://t.co/inuLn0UdXd

Cognitive PASC (COVID brain fog with measurable cognitive decline) isn’t just another flavor of long COVID. This new important study shows its a biologically distinct condition that carries features resembling early neurodegenerative processes - even after mild COVID🧵

Using MENSA and VirScan, researchers found active antibody responses to EBV, CMV, and HSV in long COVID patients, but not in recovered controls, suggesting viral reactivations may drive persistent symptoms.

Misdiagnosing AUTOIMMUNE ENCEPHALITIS as an acute psychotic episode and putting a 12-year old in a psych ward and letting her DIE is SURREAL. But unfortunately this is just one case we are aware of. As a neurologist I am sure there are hundreds of cases like this. Labeling DEADLY

Whether it's autoimmune encephalitis, PANS/PANDAS, Hashimoto encephalopathy or limbic encephalitis, doctors seem to have immense difficulty understanding that dramatic changes in behaviour come from very real physical pathology.

This will keep happening until doctors take off their denial goggles & read up on covid. A friends son was accused of drug taking & discharged from A&E. Luckily parent was a medic, went private & pushed for IVIG. Symptoms resolved. Happened again after another covid infection.

Three years after infection, the virus still leaves a fingerprint. The damage is clear - profound mitochondrial dysfunction in CD56bright NK and CD4 T cells - a problem that only appears when the immune system is pushed to respond.🧵

Bowel movements and the incidence of Parkinson's Disease After following more than 150000 people for almost 10 years

We recently interviewed Dr. Larry Afrin, a prominent physician-scientist and one of the world's authorities on mast cell disorders. Here are 4 surprising things we learned about MCAS...🧵

1) Remember the intramural NIH study about effort preference in ME/CFS? Today, a letter from several experts in the field was published in the journal Nature Communications, criticising the conclusions of the original paper.

OUR NEW LAB PAPER IS OUT showing that Urolithin A reverses high anxiety by repairing mitochondria in nucleus accumbens Big kudos to first co-authors David Mallet & Doğukan Ülgen, our amazing team, and collaborators @MitoPsychoBio @Amazentis1 Paper: https://t.co/BKp0Cvyyyr...

A mitochondrial therapy (originally called SS-31) finally approved for patients and very relevant to longevity 👏

The FDA has just approved SS-31 (elamipretide) for Barth syndrome, a rare and devastating mitochondrial disease. https://t.co/BPpcq9dshT Why is this remarkable? Because SS-31 is the first FDA-approved peptide designed to repair mitochondria directly. Here’s how it works:

Prophylactic and therapeutic itaconate treatment alleviates COVID-19-associated lung injury The effects of ITA can be attributed to 1. polarizing macrophages toward M1 or M2 phenotypes 2. macrophage self-renewal 3. macrophage proliferation Open Access https://t.co/IQ5PZ9lN0L

Could Yakult be a sleep solution? Sounds ridiculous. But one study showed it might help. 94 medical students. High stress. Those who drank Lactobacillus casei Shirota (the strain in Yakult) kept their deep sleep. The placebo group didn’t. And it’s not the only one.