Julius Ryan Pronto
@jrpronto
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Postdoctoral researcher at the @niels_voigt lab focusing on atrial fibrillation mechanisms involving the mitochondria @yourUMG || Photo by @Swen_Pfoertner
Göttingen, Germany
Joined August 2010
@jrpronto et al at found that in #AFib #mitochondria of atrial CMs take up less #calcium & promote #arrhythmias. Learn how boosting mitochondrial calcium uptake may help protect against arrhythmias at https://t.co/qIHlD1G06v
@ChristophMaack @niels_voight
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@CircRes Nov 7th Issue is Out! https://t.co/IiX6g6rOKd Cover: Immunofluorescent staining of the outer mitochondrial membrane (cyan) and microtubules (magenta) in the right atrial tissue from a patient with normal sinus rhythm.
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@pakkiri et al found acute #MICU1 deficiency resulted in increased mtCa2+ accompanied by reduced cardiac function in both the RV & LV. Learn about an LV specific adaptive response that contributes to recovery of cardiac function at https://t.co/RxOWsjPyO0
@kurt_prins
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Excited to share our new work is out in @CircRes ! We show, for the first time, that intermembrane space (IMS) calcium in the mitochondria of cardiac myocytes does not just follow cytosolic calcium! We demonstrate that calcium in the IMS is significant; RyR2 hyperactivity
ahajournals.org
BACKGROUND: Mitochondrial dysfunction caused by abnormally high RyR2 (ryanodine receptor) activity is a common finding in cardiovascular diseases. Mechanisms linking RyR2 gain of function with...
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Proud to share that my PhD work on mitochondrial dysfunction in atrial fibrillation is now online in @CircRes
https://t.co/1IGWRByXC1 Thanks to @niels_voigt and @ChristophMaack for the immense support and trust to work on this project, and to all co-authors who worked with us!
It’s been over 10 years since we began this journey with @ChristophMaack exploring mitochondrial dysfunction in #AFib. Now we’ve reached an important milestone: Our work is out in @CircRes! We show for the first time that impaired Ca²⁺ uptake into mitochondria is a hallmark of
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Just heading back from a very successful #EWGCCE2025 meeting in Nice. @aiste_liutkute @izzy_sob Jasper Bee and @jrpronto presented exciting new data from our group — great discussions, fresh insights, and promising collaborations ahead! @EWGCCEChair @pharmaumg @YoungDZHK
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We're excited to announce Marie Klopp has successfully defended her MD thesis! A pioneering member of our team, Marie will now advance her career in pediatrics. We’re grateful for her contributions and wish her all the best.Congratulations, Marie! @pharmaumg @MBExC_de
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I am delighted to share that @aiste_liutkute defended her PhD thesis with summa cum laude! In a stellar presentation, she explored the mechanisms of laminopathy-associated #Afib. Congrats on this well-deserved success! @pharmaumg @MBExC_de @bbrundel @n_bouatianaji @dzhk_germany
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When the iPSC-derived cardiomyocytes take their job a bit too seriously…
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The Heartpatch Team was ceremonially awarded the "Preis der Deutschen Hochschulmedizin" at yesterday`s 4th "Tag der Hochschulmedizin" in Berlin 🏆👏@yourUMG @UKSH_KI_HL @dzhk_germany @uniklinika @MTiburcy @IngoEitel @Hinkel_Lab Picture: Matthias Kindler/VUD
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New paper! We provided a spotlight in @TrendsCellBio on a recent paper by Zhao et al. in @CellReports where they showed how ER-#mitochondria contact sites (ERMCS) and Ca2+ transmission are vital for ATP production during mitosis. https://t.co/nZ9nZ50Y90
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🥳 Exciting news! Thrilled to announce my new lab at @IBDMmarseille @cnrs. 🎉 We use #LiveImaging to study how the dynamic #ovary makes healthy #eggs. 🔬🥚 Please RT & follow as we push the boundaries of #Fertility research! 🔗 https://t.co/JwgCpS94PV
#AcademicTwitter #NewPI
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📃📣 📣📣September news! ➡️Great success for our 1st Training School in Wurzburg on @OroborosI, Seahorse & @IonOptix with 18 students & postdocs ➡️ International conference with 4 awardees for their great presentation: Angeliki Dajou, Hualin Fan, Matus Miklovic & David Weissman
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Excited to be part of this study on the “perfect” distance between ER and mitochondria for efficient calcium transfer! New linkers were also developed. Huge thanks to Dmitry Lim's team and great work by Giulia de Matteis! #Research #CalciumTransfer
https://t.co/kug3GLOyxa
nature.com
Communications Biology - The distance-dependence analysis of ER-mitochondria Ca2+ transfer suggests that a distance of ∼20 nm between the organelles ensures maximal efficiency of...
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Just published‼️#EHJ All-in-one systematic review describing impact of dietary patterns and components on #Afib 👉 https://t.co/w5mq8STgKb ✅clinical data ✅mechanisms ✅gaps in knowledge 💪5026 articles screened 💪504 articles included 💪90 pages of tables summarizing data
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What an energising meeting on cardiac metabolism in beautiful Würzburg! Thanks to @EU_METAHEART @ChristophMaack for the opportunity to participate in the training school and present our work to such an excellent audience @niels_voigt @KatrinStreckf @IonOptix @OroborosI @Agilent
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Co-chairing Mechano-energetic uncoupling work group 4 session @EU_METAHEART with @KatrinStreckf 💪🏻🫀Huge thanks to all our amazing speakers. Another fantastic afternoon of metabolism discussion @hiranprag @Mito_Redox @OchDr @AliceMarino_
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New press release on our @CircAHA paper with @dzhk_germany & @yourUMG: "Defective Ca2+ 'Shock Absorber' in heart muscle cells contributes to AF." Learn how impaired calcium buffering drives #AFib. @funshofaks @HubrichtD @FleurEMason @MBExC_de @pharmaumg
https://t.co/bjoE0VMpaE
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#NewIssue Ft cover art by Kehuitang Art Studio. He et al. reveal a protective effect of acetate against metabolic and cognitive impairments caused by sleep disruption. Inspired by Monet’s famous Water Lilies paintings, a “mitochondrion” boat drifts in a lotus pond full of water
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Great talk by @niels_voigt on mitochondrial dysfunction in atrial fibrillation #AF
#ESCCongress #ESCBasicScience
Next #ESCBasicscience session coming up: Novel players in atrial fibrillation: looking outside the box Room San Antonio at 16:15 @AnaMGmez4 @Barbara_Casadei @niels_voigt @Dominik_Linz
#ESCCongress
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